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A contextual framework for characterizing motility and chemotaxis mutants in Dictyostelium discoideum.

Data up to Jan 2025

Published2002
Citations53
References68

Total Citations Per Year

Abstract

References (68)

LEUKOCYTE LOCOMOTION AND CHEMOTAXIS

1973 • 1,709 citations

Genetic Control of the Cell Division Cycle in Yeast

1974 • 1,588 citations

Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination

1987 • 984 citations

Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors.

1977 • 905 citations

Cell movements : from molecules to motility

1992 • 710 citations

The Development of Dictyostelium Discoideum

1982 • 664 citations

Chemotaxis in Eukaryotic Cells: A Focus on Leukocytes and Dictyostelium

1988 • 623 citations

Leukocyte polarization in cell migration and immune interactions

1999 • 622 citations

Chapter 2 Cultivation and Synchronous Morphogenesis of Dictyostelium under Controlled Experimental Conditions

1987 • 610 citations

The Saccharomyces cerevisiae Cell Cycle

1981 • 539 citations

The acrasin activity of adenosine-3',5'-cyclic phosphate.

1967 • 494 citations

Dictyostelium: Evolution, Cell Biology, and the Development of Multicellularity

2001 • 482 citations

The Cell Cycle

1989 • 468 citations

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

1999 • 444 citations

Adenosine 3′,5′-Monophosphate Waves in Dictyostelium discoideum : a Demonstration by Isotope Dilution—Fluorography

1981 • 393 citations

Signal Propagation during Aggregation in the Slime Mould Dictyostelium discoideum

1974 • 324 citations

Regulation of myosin self-assembly: phosphorylation of Dictyostelium heavy chain inhibits formation of thick filaments.

1980 • 252 citations

Quantitative analysis of cell motility and chemotaxis in Dictyostelium discoideum by using an image processing system and a novel chemotaxis chamber providing stationary chemical gradients.

1989 • 205 citations

Chemotactic reorientation of granulocytes stimulated with micropipettes containing fmet-leu-phe

1981 • 187 citations

Chemoattractant-elicited increases in myosin phosphorylation in dictyostelium

1985 • 173 citations

Developmental signal transduction pathways uncovered by genetic suppressors

1996 • 173 citations

The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients

2000 • 173 citations

Integration of Signaling Networks that Regulate Dictyostelium Differentiation

1999 • 167 citations

Motion Analysis of Living Cells

1997 • 167 citations

A Molecular Network That Produces Spontaneous Oscillations in Excitable Cells ofDictyostelium

1998 • 165 citations

Relationship of pseudopod extension to chemotactic hormone‐induced actin polymerization in amoeboid cells

1988 • 161 citations

A cAMP-phosphodiesterase controls PKA-dependent differentiation

1998 • 155 citations

The Use of Computers in Understanding How Animal Cells Crawl

1995 • 155 citations

The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients

2000 • 153 citations

The unconventional myosin encoded by the myoA gene plays a role in Dictyostelium motility.

1993 • 148 citations

Myosin IB null mutants of Dictyostelium exhibit abnormalities in motility

1991 • 143 citations

A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium

1991 • 129 citations

Targeted disruption of the ABP-120 gene leads to cells with altered motility.

1992 • 125 citations

Role of PKA in the Timing of Developmental Events in Dictyostelium Cells

1998 • 108 citations

DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase.

1992 • 108 citations

A computer-assisted system for reconstructing and interpreting the dynamic three-dimensional relationships of the outer surface, nucleus and pseudopods of crawling cells

1998 • 106 citations

Overexpression of Dd PK2 protein kinase causes rapid development and affects the intracellular cAMP pathway of Dictyostelium discoideum

1992 • 100 citations

Multiple roles for cAMP-dependent protein kinase during Dictyostelium development

1992 • 99 citations

Three‐dimensional dynamics of pseudopod formation and the regulation of turning during the motility cycle of Dictyostelium

1994 • 98 citations

Effects of cAMP on single cell motility in Dictyostelium.

1984 • 97 citations

Chemoattractant-elicited increases in Dictyostelium myosin phosphorylation are due to changes in myosin localization and increases in kinase activity.

1987 • 97 citations

Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells.

1994 • 93 citations

[3] Micropore filter methods for leukocyte chemotaxis

1988 • 86 citations

Frequency and orientation of pseudopod formation of Dictyostelium discoideum amebae chemotaxing in a spatial gradient: Further evidence for a temporal mechanism

1987 • 84 citations

RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation

2001 • 84 citations

ADictyostelium myosin I plays a crucial role in regulating the frequency of pseudopods formed on the substratum

1996 • 81 citations

Dictyostelium amebae alter motility differently in response to increasing versus decreasing temporal gradients of cAMP.

1985 • 81 citations

Regulation of myosin self-assembly : phosphorylation of Dictyostelium heavy chain inhibits thick filament formation.

1980 • 80 citations

Shaping up for shipping out: PLC? signaling of morphology changes in EGF-stimulated fibroblast migration

1999 • 80 citations

Behavior of Dictyostelium amoebae is regulated primarily by the temporal dynamic of the natural cAMP wave

1992 • 79 citations

Evidence that the RdeA protein is a component of a multistep phosphorelay modulating rate of development in Dictyostelium

1998 • 73 citations

Chemoresponsiveness to cAMP and Folic Acid during Growth, Development, and Dedifferentiation in Dictyostelium discoideum

1981 • 70 citations

The Internal Phosphodiesterase RegA Is Essential for the Suppression of Lateral Pseudopods duringDictyosteliumChemotaxis

2000 • 66 citations

cAMP-mediated inhibition of intracellular particle movement and actin reorganization in Dictyostelium.

1989 • 65 citations

Amebae of Dictyostelium discoideum respond to an increasing temporal gradient of the chemoattractant cAMP with a reduced frequency of turning: Evidence for a temporal mechanism in ameboid chemotaxis

1987 • 64 citations

3D-DIASemb: A Computer-Assisted System for Reconstructing and Motion Analyzing in 4D Every Cell and Nucleus in a Developing Embryo

2002 • 60 citations

Computer-assisted three-dimensional reconstruction and motion analysis of living, crawling cells

1999 • 54 citations

Phosphorylation of the myosin regulatory light chain plays a role in motility and polarity duringDictyosteliumchemotaxis

2002 • 50 citations

Three‐dimensional reconstruction and motion analysis of living, crawling cells

2000 • 49 citations

Constitutively Active Protein Kinase A Disrupts Motility and Chemotaxis inDictyostelium discoideum

2003 • 48 citations

T cell syncytia induced by HIV release T cell chemoattractants: demonstration with a newly developed single cell chemotaxis chamber

1998 • 39 citations

Molecular basis of localized responses during chemotaxis in amoebae and leukocytes

1999 • 37 citations

Selection of chemotaxis mutants of Dictyostelium discoideum.

1987 • 34 citations

Chemotaxis to cAMP and slug migration in Dictyostelium both depend on migA, a BTB protein.

1997 • 33 citations

Identification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyostelium

2001 • 30 citations

Cell Behavior and Actomyosin Organization in Dictyostelium During Substrate Exploration.

1991 • 23 citations

Behavioral studies into the mechanism of eukaryotic chemotaxis

1990 • 18 citations

The Motile Behavior of Amoebae in the Aggregation Wave in Dictyostelium Discoideum

1993 • 18 citations

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A contextual framework for characterizing motility and chemotaxis mutants in… (2002) – Journal of Muscle Research and Cell Motility | Metascience Observatory Explorer