A contextual framework for characterizing motility and chemotaxis mutants in Dictyostelium discoideum.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (68)
LEUKOCYTE LOCOMOTION AND CHEMOTAXIS
1973 • 1,709 citations
Genetic Control of the Cell Division Cycle in Yeast
1974 • 1,588 citations
Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination
1987 • 984 citations
Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors.
1977 • 905 citations
Cell movements : from molecules to motility
1992 • 710 citations
The Development of Dictyostelium Discoideum
1982 • 664 citations
Chemotaxis in Eukaryotic Cells: A Focus on Leukocytes and Dictyostelium
1988 • 623 citations
Leukocyte polarization in cell migration and immune interactions
1999 • 622 citations
Chapter 2 Cultivation and Synchronous Morphogenesis of Dictyostelium under Controlled Experimental Conditions
1987 • 610 citations
The Saccharomyces cerevisiae Cell Cycle
1981 • 539 citations
The acrasin activity of adenosine-3',5'-cyclic phosphate.
1967 • 494 citations
Dictyostelium: Evolution, Cell Biology, and the Development of Multicellularity
2001 • 482 citations
The Cell Cycle
1989 • 468 citations
Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
1999 • 444 citations
Adenosine 3′,5′-Monophosphate Waves in Dictyostelium discoideum : a Demonstration by Isotope Dilution—Fluorography
1981 • 393 citations
Signal Propagation during Aggregation in the Slime Mould Dictyostelium discoideum
1974 • 324 citations
Regulation of myosin self-assembly: phosphorylation of Dictyostelium heavy chain inhibits formation of thick filaments.
1980 • 252 citations
Quantitative analysis of cell motility and chemotaxis in Dictyostelium discoideum by using an image processing system and a novel chemotaxis chamber providing stationary chemical gradients.
1989 • 205 citations
Chemotactic reorientation of granulocytes stimulated with micropipettes containing fmet-leu-phe
1981 • 187 citations
Chemoattractant-elicited increases in myosin phosphorylation in dictyostelium
1985 • 173 citations
Developmental signal transduction pathways uncovered by genetic suppressors
1996 • 173 citations
The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients
2000 • 173 citations
Integration of Signaling Networks that Regulate Dictyostelium Differentiation
1999 • 167 citations
Motion Analysis of Living Cells
1997 • 167 citations
A Molecular Network That Produces Spontaneous Oscillations in Excitable Cells ofDictyostelium
1998 • 165 citations
Relationship of pseudopod extension to chemotactic hormone‐induced actin polymerization in amoeboid cells
1988 • 161 citations
A cAMP-phosphodiesterase controls PKA-dependent differentiation
1998 • 155 citations
The Use of Computers in Understanding How Animal Cells Crawl
1995 • 155 citations
The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients
2000 • 153 citations
The unconventional myosin encoded by the myoA gene plays a role in Dictyostelium motility.
1993 • 148 citations
Myosin IB null mutants of Dictyostelium exhibit abnormalities in motility
1991 • 143 citations
A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium
1991 • 129 citations
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
1992 • 125 citations
Role of PKA in the Timing of Developmental Events in Dictyostelium Cells
1998 • 108 citations
DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase.
1992 • 108 citations
A computer-assisted system for reconstructing and interpreting the dynamic three-dimensional relationships of the outer surface, nucleus and pseudopods of crawling cells
1998 • 106 citations
Overexpression of Dd PK2 protein kinase causes rapid development and affects the intracellular cAMP pathway of Dictyostelium discoideum
1992 • 100 citations
Multiple roles for cAMP-dependent protein kinase during Dictyostelium development
1992 • 99 citations
Three‐dimensional dynamics of pseudopod formation and the regulation of turning during the motility cycle of Dictyostelium
1994 • 98 citations
Effects of cAMP on single cell motility in Dictyostelium.
1984 • 97 citations
Chemoattractant-elicited increases in Dictyostelium myosin phosphorylation are due to changes in myosin localization and increases in kinase activity.
1987 • 97 citations
Expression of a myosin regulatory light chain phosphorylation site mutant complements the cytokinesis and developmental defects of Dictyostelium RMLC null cells.
1994 • 93 citations
[3] Micropore filter methods for leukocyte chemotaxis
1988 • 86 citations
Frequency and orientation of pseudopod formation of Dictyostelium discoideum amebae chemotaxing in a spatial gradient: Further evidence for a temporal mechanism
1987 • 84 citations
RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation
2001 • 84 citations
ADictyostelium myosin I plays a crucial role in regulating the frequency of pseudopods formed on the substratum
1996 • 81 citations
Dictyostelium amebae alter motility differently in response to increasing versus decreasing temporal gradients of cAMP.
1985 • 81 citations
Regulation of myosin self-assembly : phosphorylation of Dictyostelium heavy chain inhibits thick filament formation.
1980 • 80 citations
Shaping up for shipping out: PLC? signaling of morphology changes in EGF-stimulated fibroblast migration
1999 • 80 citations
Behavior of Dictyostelium amoebae is regulated primarily by the temporal dynamic of the natural cAMP wave
1992 • 79 citations
Evidence that the RdeA protein is a component of a multistep phosphorelay modulating rate of development in Dictyostelium
1998 • 73 citations
Chemoresponsiveness to cAMP and Folic Acid during Growth, Development, and Dedifferentiation in Dictyostelium discoideum
1981 • 70 citations
The Internal Phosphodiesterase RegA Is Essential for the Suppression of Lateral Pseudopods duringDictyosteliumChemotaxis
2000 • 66 citations
cAMP-mediated inhibition of intracellular particle movement and actin reorganization in Dictyostelium.
1989 • 65 citations
Amebae of Dictyostelium discoideum respond to an increasing temporal gradient of the chemoattractant cAMP with a reduced frequency of turning: Evidence for a temporal mechanism in ameboid chemotaxis
1987 • 64 citations
3D-DIASemb: A Computer-Assisted System for Reconstructing and Motion Analyzing in 4D Every Cell and Nucleus in a Developing Embryo
2002 • 60 citations
Computer-assisted three-dimensional reconstruction and motion analysis of living, crawling cells
1999 • 54 citations
Phosphorylation of the myosin regulatory light chain plays a role in motility and polarity duringDictyosteliumchemotaxis
2002 • 50 citations
Three‐dimensional reconstruction and motion analysis of living, crawling cells
2000 • 49 citations
Constitutively Active Protein Kinase A Disrupts Motility and Chemotaxis inDictyostelium discoideum
2003 • 48 citations
T cell syncytia induced by HIV release T cell chemoattractants: demonstration with a newly developed single cell chemotaxis chamber
1998 • 39 citations
Molecular basis of localized responses during chemotaxis in amoebae and leukocytes
1999 • 37 citations
Selection of chemotaxis mutants of Dictyostelium discoideum.
1987 • 34 citations
Chemotaxis to cAMP and slug migration in Dictyostelium both depend on migA, a BTB protein.
1997 • 33 citations
Identification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyostelium
2001 • 30 citations
Cell Behavior and Actomyosin Organization in Dictyostelium During Substrate Exploration.
1991 • 23 citations
Behavioral studies into the mechanism of eukaryotic chemotaxis
1990 • 18 citations
The Motile Behavior of Amoebae in the Aggregation Wave in Dictyostelium Discoideum
1993 • 18 citations
Cited By (0)
No citing papers found in database