Calcium facilitates endogenous proteolysis of the EGF receptor-kinase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Epidermal Growth Factor

1979 • 2,964 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Human erythrocyte membrane glycoprotein: A re-evaluation of the molecular weight as determined by SDS polyacrylamide gel electrophoresis

1971 • 552 citations

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.

1979 • 530 citations

Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

1980 • 510 citations

Biochemistry and physiology of the skin

1983 • 487 citations

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

1978 • 448 citations

Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A-431 cells

1981 • 426 citations

A Neutral, Calcium-activated Proteinase from the Soluble Fraction of Rat Brain

1964 • 425 citations

A Ca²⁺ion-activated protease possibly involved in myofibrillar protein turnover. Purification from porcine muscle

1976 • 413 citations

A calcium(2+) ion-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme

1976 • 395 citations

Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1981 • 392 citations

Ca2+-SPECIFIC REMOVAL OF Z LINES FROM RABBIT SKELETAL MUSCLE

1972 • 374 citations

Rapid isolation of plasma membranes in high yield from cultured fibroblasts

1977 • 304 citations

Ca2+-dependent protease in human platelets. Specific cleavage of platelet polypeptides in the presence of added Ca2+.

1977 • 274 citations

Canine cardiac calcium‐dependent proteases: Resolution of two forms with different requirements for calcium

1980 • 267 citations

Human transforming growth factors induce tyrosine phosphorylation of EGF receptors

1981 • 244 citations

Activation of skeletal muscle phosphorylase kinase by calcium ions. II. Identification of the kinase activating factor as a proteolytic enzyme

1968 • 238 citations

Neurofilament disguise, destruction and discipline

1975 • 233 citations

Micromolar Calcium Stimulates Proteolysis and Glutamate Binding in Rat Brain Synaptic Membranes

1981 • 180 citations

Estrogen binding proteins of calf uterus. Molecular and functional characterization of the receptor transforming factor: A Ca2+-activated protease.

1977 • 167 citations

Characterization by electrophoresis of epidermal growth factor stimulated phosphorylation using A-431 membranes

1980 • 153 citations

Calcium-promoted changes of the human erythrocyte membrane. Involvement of spectrin, transglutaminase, and a membrane-bound protease.

1977 • 153 citations

Identification of epidermal growth factor receptors in a hyperproducing human epidermoid carcinoma cell line.

1979 • 153 citations

Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation

1979 • 140 citations

Autolysis of Calcium-Activated Neutral Protease of Chicken Skeletal Muscle1

1981 • 130 citations

Purified EGF receptor–kinase interacts specifically with antibodies to Rous sarcoma virus transforming protein

1981 • 130 citations

Direct linkage of epidermal growth factor to its receptor

1979 • 113 citations

Isolation of the human placenta receptor for epidermal growth factor-urogastrone

1979 • 80 citations

Calcium-dependent proteolytic activity in rat liver: Identification of two proteases with different calcium requirements

1981 • 80 citations

Anti-pp60src antibodies are substrates for EGF-stimulated protein kinase

1981 • 78 citations

Calcium-Dependent Neutral Proteases, Widespread Occurrence of a Species of Protease Active at Lower Concentrations of Calcium1

1981 • 72 citations

Calcium-induced erythrocyte membrane changes. The role of adsorption of cytosol proteins and proteases

1979 • 63 citations

Calcium effects on human erythrocyte membrane proteins

1977 • 59 citations

Controlled proteolysis of EGF receptors: Evidence for transmembrane distribution of the EGF binding and phosphate acceptor sites

1980 • 51 citations

Rapid and specific enhancement of phosphorylation of two normal rat kidney cell membrane polypeptides of Mr = 170,000 and 150,000 by epidermal growth factor in vitro.

1981 • 44 citations

Direct linkage of EGF to its receptor: Characterization and biological relevance

1980 • 39 citations

The EGF receptor-kinase has multiple phosphorylation sites

1982 • 38 citations

Protein phosphorylation in human placenta stimulation by epidermal growth factor

1980 • 38 citations

Neurofilaments

1976 • 14 citations