Xenopus Oocytes: Endogenous Electrophysiological Characteristics

Ionic channels of excitable membranes

1985 • 7,199 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals

1972 • 1,861 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

Junctional intercellular communication: the cell-to-cell membrane channel.

1981 • 1,268 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

1986 • 979 citations

Relationships between calcium and cyclic nucleotides in cell activation.

1977 • 849 citations

Block of Stretch-Activated Ion Channels in Xenopus Oocytes by Gadolinium and Calcium Ions

1989 • 811 citations

Electrogenic sodium pump in nerve and muscle cells.

1972 • 787 citations

Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+

1986 • 775 citations

Use of Frog Eggs and Oocytes for the Study of Messenger RNA and its Translation in Living Cells

1971 • 774 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

The inositol tris/tetrakisphosphate pathway—demonstration of Ins(l,4,5)P3 3-kinase activity in animal tissues

1986 • 702 citations

Contractions induced by a calcium‐triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells.

1975 • 684 citations

The Use ofXenopusOocytes for the Study of Ion Channel

1987 • 649 citations

A transient calcium‐dependent chloride current in the immature Xenopus oocyte.

1983 • 627 citations

Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation.

1990 • 626 citations

Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.

1982 • 618 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Cholinergic and catecholaminergic receptors in the Xenopus oocyte membrane

1982 • 475 citations

A calcium-dependent transient outward current in Xenopus laevis oocytes

1982 • 473 citations

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.

1987 • 442 citations

Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons

1989 • 431 citations

Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes

1988 • 396 citations

Chloride current induced by injection of calcium into Xenopus oocytes.

1984 • 395 citations

Fluoride complexes of aluminium or beryllium act on G-proteins as reversibly bound analogues of the gamma phosphate of GTP.

1987 • 383 citations

Expression of functional acetylcholine receptor from cloned cDNAs

1984 • 366 citations

Molecular mechanisms of transmembrane signalling

1985 • 352 citations

Intracellular calcium injection causes increased potassium conductance in Aplysia nerve cells

1972 • 349 citations

A Spatial-Temporal Model of Cell Activation

1988 • 347 citations

Toxins in the characterization of potassium channels

1989 • 340 citations

Signal sorting and amplification through G protein-coupled receptors

1989 • 338 citations

Cyclic Nucleotide-dependent Protein Kinases

1970 • 334 citations

Hormone-evoked calcium release from intracellular stores is a quantal process

1989 • 312 citations

Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated Cl- channels in Xenopus oocytes.

1990 • 309 citations

Temporal and spatial dynamics of the periodic increase in intracellular free calcium at fertilization of golden hamster eggs

1986 • 308 citations

Protein kinase C activation induces conductance changes in Hermissenda photoreceptors like those seen in associative learning

1986 • 289 citations

Voltage clamp analysis of two inward current mechanisms in the egg cell membrane of a starfish.

1975 • 286 citations

Electrical Properties of Egg Cell Membranes

1979 • 277 citations

Muscle chloride channels.

1987 • 257 citations

Activation of frog (Xenopus laevis) eggs by inositol trisphosphate. I. Characterization of Ca2+ release from intracellular stores.

1985 • 255 citations

[Na] and [K] dependence of the Na/K pump current-voltage relationship in guinea pig ventricular myocytes.

1989 • 254 citations

Inositol 1,4,5-trisphosphate mimics muscarinic response in Xenopus oocytes

1985 • 249 citations

Tetraethylammonium ions and the potassium permeability of excitable cells

1983 • 248 citations

Voltage dependence of Na/K pump current in isolated heart cells

1985 • 240 citations

Neuronal Phosphoproteins: Physiological and Clinical Implications

1984 • 216 citations

Localized All-or-None Calcium Liberation by Inositol Trisphosphate

1990 • 205 citations

Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes

1981 • 197 citations

Acetylcholine receptors in the oocyte membrane

1977 • 194 citations

Goprotein as signal transducer in the pertussis toxin-sensitive phosphatidylinositol pathway

1990 • 181 citations

Potassium channels expressed from rat brain cDNA have delayed rectifier properties

1988 • 173 citations

Characterization of a membrane protein from brain mediating the inhibition of inositol 1,4,5-trisphosphate receptor binding by calcium

1988 • 168 citations

The metabolism of tris- and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes.

1987 • 164 citations

Inositol trisphosphate-induced membrane potential oscillations in Xenopus oocytes.

1988 • 160 citations

Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 3',5'‐cyclic monophosphate.

1984 • 153 citations

Effects of defolliculation on membrane current responses of Xenopus oocytes.

1989 • 147 citations

Electrical currents through full-grown and maturing Xenopus oocytes.

1979 • 138 citations

The use of Xenopus oocytes to probe synaptic communication

1988 • 138 citations

Identification and properties of cyclic nucleotide phosphodiesterases

1982 • 135 citations

Two calcium‐activated chloride conductances in Xenopus laevis oocytes permeabilized with the ionophore A23187.

1989 • 130 citations

Inositol trisphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influx in Xenopus laevis oocytes.

1988 • 129 citations

Role of calcium mobilization in mediation of acetylcholine‐evoked chloride currents in Xenopus laevis oocytes.

1985 • 124 citations

Changes in intracellular calcium and in membrane currents evoked by injection of inositol trisphosphate into Xenopus oocytes

1986 • 123 citations

Voltage dependence of the rheogenic Na+/K+ ATPase in the membrane of oocytes ofXenopus laevis

1986 • 121 citations

Serotonin receptors induced by exogenous messenger RNA in Xenopus oocytes

1983 • 118 citations

Ca channels induced in Xenopus oocytes by rat brain mRNA

1987 • 118 citations

Spatial localization of the stimulus‐induced rise in cytosolic Ca²⁺ in bovine adrenal chromaffin cells

1989 • 112 citations

The Biosynthesis of Biologically Active Proteins in mRNA-MicroinjectedXenopusOocyte

1985 • 111 citations

Sodium channels induced by depolarization of the Xenopus laevis oocyte.

1982 • 111 citations

Characterization of a chloride conductance activated by hyperpolarization in Aplysia neurones.

1983 • 109 citations

Characterization and regulation of prostaglandin and leukotriene receptors: An overview

1986 • 103 citations

Inhibition of oocyte maturation by theophylline: Possible mechanism of action

1976 • 98 citations

Calcium, potassium, and sodium exchange by full-grown and maturing Xenopus laevis oocytes

1977 • 93 citations

The involvement of inositol 1,4,5‐trisphosphate and calcium in the two‐component response to acetylcholine in Xenopus oocytes.

1987 • 90 citations

Cyclic AMP-mediated control of meiosis: effects of progesterone, cholera toxin, and membrane-active drugs in Xenopus laevis oocytes.

1982 • 87 citations

Maturation of Xenopus oocytes

1977 • 85 citations

Inositol 1,4,5-trisphosphate and intracellular Ca2+ homeostasis in clonal pituitary cells (GH3). Translocation of Ca2+ into mitochondria from a functionally discrete portion of the nonmitochondrial store.

1986 • 80 citations

Voltage-dependent inactivation of a calcium channel.

1981 • 75 citations

Inositol phosphate formation and chloride current responses induced by acetylcholine and serotonin through GTP-binding proteins in Xenopus oocyte after injection of rat brain messenger RNA

1987 • 74 citations

Inositol trisphosphate activates a voltage-dependent calcium influx in Xenopus oocytes

1987 • 72 citations

Regulation of the amphibian oocyte plasma membrane ion permeability by cytoplasmic factors during the first meiotic division

1977 • 71 citations

Electrical membrane properties of the Xenopus laevis oocyte during progesterone-induced meiotic maturation

1981 • 71 citations

Determination of ionic permeability coefficients of the plasma membrane of Xenopus laevis oocytes under voltage clamp.

1989 • 70 citations

Acetylcholine and phorbol esters inhibit potassium currents evoked by adenosine and cAMP in Xenopus oocytes.

1985 • 68 citations

A calcium-independent chloride current activated by hyperpolarization in Xenopus oocytes

1988 • 67 citations

Detection and Transduction of Physical Stimuli in Plants

1987 • 67 citations

The activities and concentrations of sodium and potassium in toad oocytes

1969 • 67 citations

Diacylglycerol downregulates junctional membrane permeability. TMB-8 blocks this effect

1985 • 63 citations

Nonlinearity and facilitation in phosphoinositide signaling studied by the use of caged inositol trisphosphate in Xenopus oocytes

1989 • 62 citations

Injection of inositol 1, 3, 4, 5-tetrakisphosphate into Xenopus oocytes generates a chloride current dependent upon intracellular calcium

1987 • 59 citations

Membrane currents elicited by divalent cations in Xenopus oocytes.

1989 • 59 citations

Inositol Trisphosphate and Calcium Signaling

1988 • 59 citations

Effect of inositol trisphosphate and calcium on oscillating elevations of intracellular calcium in Xenopus oocytes.

1990 • 58 citations

Activity coefficients of intracellular Na+ and K+ during development of frog oocytes

1978 • 55 citations

Inositol phosphate formation and chloride current responses induced by acetylcholine and serotonin through GTP-binding proteins in oocyte after injection of rat brain messenger RNA

1987 • 55 citations

Regulatory changes of membrane transport and ouabain binding during progesterone-induced maturation ofXenopus oocytes

1984 • 52 citations

Neurology and Neurobiology

1985 • 52 citations

A delayed rectifier potassium current in Xenopus oocytes

1990 • 51 citations

Hemispheric asymmetry of rapid chloride responses to inositol trisphosphate and calcium in Xenopus oocytes

1988 • 51 citations

Vasopressin: Mechanisms of Receptor Activation

1983 • 51 citations

DL-Myo-inositol 1,4,5-trisphosphorothioate mobilizes intracellular calcium in Swiss 3T3 cells and Xenopus oocytes

1988 • 50 citations

Voltage dependence of Na/K pump current inXenopus oocytes

1988 • 49 citations

Induction and disappearance of excitability in the oocyte of Xenopus laevis: a voltage‐clamp study.

1984 • 48 citations

Acetylcholine promotes progesterone‐induced maturation of Xenopus oocytes

1984 • 48 citations

Recording of single γ-aminobutyrate- and acetylcholine-activated receptor channels translated by exogenous mRNA in Xenopus oocytes

1983 • 47 citations

Inactivation of calcium-activated chloride conductance in Xenopus oocytes: roles of calcium and protein kinase C

1990 • 45 citations

Voltage dependence of the Na−K ATPase: measurements of ouabain-dependent membrane current and ouabain binding in oocytes ofXenopus laevis

1988 • 44 citations

Hormonal activation of ionic currents in follicle-enclosed Xenopus oocytes.

1987 • 44 citations

Adenosine-induced K+ current in Xenopus oocyte and the role of adenosine 3',5'-monophosphate.

1985 • 43 citations

Acetylcholine‐ and inositol 1,4,5‐trisphosphate‐induced calcium mobilization in Xenopus laevis oocytes

1986 • 40 citations

Coupling of inositol phospholipid hydrolysis to peptide hormone receptors expressed from adrenal and pituitary mRNA in Xenopus laevis oocytes.

1987 • 39 citations

ATP-evoked membrane responses inXenopus oocytes

1986 • 37 citations

mRNA-directed synthesis and insertion of functional amino acid receptors in Xenopus laevis oocytes

1987 • 37 citations

Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.

1986 • 36 citations

β-Adrenergic induced K ⁺ current in Xenopus oocytes: role of cAMP, inhibition by muscarinic agents

1985 • 36 citations

The lonic permeability of the Amphibian oocyte in the presence or absence of external calcium

1973 • 35 citations

Oscillatory chloride current evoked by temperature jumps during muscarinic and serotonergic activation in Xenopus oocyte.

1987 • 34 citations

The involvement of a calmodulin‐dependent phosphodiesterase in the negative control of carbamylcholine on cyclic AMP levels in dog thyroid slices

1983 • 34 citations

Membrane currents elicited by prostaglandins, atrial natriuretic factor and oxytocin in follicle‐enclosed Xenopus oocytes.

1989 • 33 citations

Cyclic GMP mimics the muscarinic response in Xenopus oocytes: identity of ionic mechanisms.

1982 • 32 citations

Metabolism of Inositol Pentakisphosphate to Inositol Hexakisphosphate in Xenopus laevis Oocytes

1989 • 32 citations

Tetrodotoxin-sensitive sodium current in native Xenopus oocytes

1987 • 31 citations

Short-and long-term desensitization of serotonergic response in Xenopus oocytes injected with brain RNA: roles for inositol 1,4,5-trisphosphate and protein kinase C

1990 • 29 citations

Dual regulation by protein kinase C of the muscarinic response in Xenopus oocytes

1989 • 28 citations

Inositol 1, 4, 5-trisphosphate-induced calcium mobilization is localized in Xenopus oocytes

1989 • 28 citations

Evidence for intracellular sodium pumps in permeabilized Xenopus laevis oocytes

1989 • 26 citations

Extracellular calcium participates in responses to acetylcholine in Xenopus oocytes

1990 • 26 citations

A hyperpolarization-activated chloride current in xenopus laevis oocytes under voltage-clamp

1983 • 25 citations

A slowly inactivating potassium current in native oocytes of Xenopus laevis

1990 • 25 citations

The effects of membrane potential on active and passive sodium transport in Xenopus oocytes.

1987 • 24 citations

Angiotensin II stimulates an endogenous response in Xenopus laevis ovarian follicles

1989 • 23 citations

Structure and Dynamics of FD Coat Protein

1986 • 22 citations

Characterization of the soluble cyclic nucleotide phosphodiesterases in xenopus laevis oocytes

1982 • 21 citations

Activation of ionic currents in Xenopus oocytes by corticotropin-releasing peptides

1988 • 21 citations

Transient potassium current in native Xenopus oocytes

1988 • 21 citations

Membrane currents elicited by porcine vasoactive intestinal peptide (VIP) in follicle-enclosed Xenopus oocytes

1987 • 20 citations

Microinjection of inositol 1,2‐(cyclic)‐4,5‐trisphosphate, inositol 1,3,4,5‐tetrakisphosphate, and inositol 1,4,5‐trisphosphate into intact Xenopus oocytes can induce membrane currents independent of extracellular calcium

1989 • 20 citations

Characterization of a Na+-K+-2Cl− cotransport system in oocytes from Xenopus laevis

1990 • 20 citations

Further characterization of the slow muscarinic responses inXenopus oocytes

1987 • 20 citations

Channels from genes: The oocyte as an expression system

1984 • 20 citations

Amino acid receptors from insect muscle: electrophysiological characterization in Xenopus oocytes following expression by injection of mRNA

1990 • 19 citations

Metabolism of the biologically active inositol phosphates Ins(1,4,5)P3 and Ins(1,3,4,5)P4 by ovarian follicles of Xenopus laevis

1990 • 17 citations

Calmodulin modulates the cyclic AMP level in Xenopus oocyte

1983 • 17 citations

Potassium exchange in the whole cell, cytoplasm, and nucleus of amphibian oocytes

1980 • 16 citations

External Na+ inhibits Ca2+-ionophore activation of Xenopus eggs

1985 • 16 citations

Calcium-dependent chloride currents elicited by injection of ethanol into Xenopus oocytes

1989 • 15 citations

Neurochemistry: A Practical Approach

1988 • 15 citations

The endegenous muscarinic acetylcholine receptor in Xenopus oocytes is of the M3 subtype

1988 • 14 citations

Dissociation of acetylcholine- and cyclic GMP-induced currents inXenopu oocytes

1987 • 11 citations

Melatonin receptor mRNA expression in Xenopus oocytes: Inhibition of G-protein-activated response

1991 • 11 citations

Vasoactive intestinal peptide (VIP) induces a K+ current in the Xenopus oocyte membrane

1987 • 11 citations

E-series prostaglandins activate cAMP-mediated potassium currents in follicle-enclosed xenopus oocyte

1989 • 11 citations

Ionic and charge-displacement currents evoked by temperature jumps in Xenopus oocytes

1989 • 11 citations

Formation of inositol pentakisphosphate by ovarian follicles of Xenopus lavevis from metabolism of inositol (1,4,5)trisphosphate and inositol (1,3,4,5)tetrakisphosphate and from receptor activation

1990 • 9 citations

Dependence of the electrogenic pump current of Xenopus oocytes on external potassium

1987 • 9 citations

Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation

1974 • 8 citations

Invertebrate (insect) and vertebrate synaptic receptor-ion channels: a comparison using the Xenopus oocyte technique

1990 • 1 citations

Muscarinic and purinergic slow membrane responses in Xenopus oocytes.

1987 • 1 citations