A PET study of D 1 -like dopamine receptor ligand binding

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

1980 • 1,579 citations

Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine

1992 • 1,420 citations

D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

1991 • 1,365 citations

Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects.

1996 • 1,275 citations

Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method

1997 • 1,147 citations

Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

1986 • 847 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 768 citations

Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies.

1993 • 610 citations

The ECAT EXACT HR

1994 • 574 citations

Dopamine receptors: Molecular biology, biochemistry and behavioural aspects

1994 • 489 citations

Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents

1995 • 483 citations

Kinetic Analysis of Central [¹¹C]Raclopride Binding to D₂-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium Analysis

1989 • 454 citations

Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system

1989 • 435 citations

D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines.

1994 • 384 citations

Imaging endogenous dopamine competition with [¹¹C]raclopride in the human brain

1994 • 378 citations

D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients

1995 • 341 citations

Striatal binding of the PET ligand ¹¹C‐raclopride is altered by drugs that modify synaptic dopamine levels

1993 • 285 citations

PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride

1987 • 279 citations

Internalization of D1 Dopamine Receptor in Striatal NeuronsIn Vivoas Evidence of Activation by Dopamine Agonists

1998 • 196 citations

Quantitation of Carbon‐11‐labeled raclopride in rat striatum using positron emission tomography

1992 • 196 citations

Ultrastructural localization of D1 dopamine receptor immunoreactivity in rat striatonigral neurons and its relation with dopaminergic innervation

1996 • 191 citations

Preparation of 11C-labelled SCH 23390 for the in vivo study of dopamine D-1 receptors using positron emission tomography

1986 • 177 citations

Comparison of the Transient Equilibrium and Continuous Infusion Method for Quantitative PET Analysis of [¹¹C]Raclopride Binding

1998 • 160 citations

Positron Emission Tomography Studies on D2 and 5-HT2 Receptor Binding in Risperidone-Treated Schizophrenic Patients

1995 • 156 citations

In vivo [³H]Spiperone Binding: Evidence for Accumulation in Corpus Striatum by Agonist-Mediated Receptor Internalization

1988 • 121 citations

Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D1-dopamine receptors.

1998 • 119 citations

Effect of reserpine-induced depletion of synaptic dopamine on [11C]Raclopride binding to D2-dopamine receptors in the monkey brain

1997 • 106 citations

Effects of endogenous dopamine on measures of [¹⁸F]N‐methylspiroperidol binding in the basal ganglia: Comparison of simulations and experimental results from PET studies in baboons

1991 • 105 citations

Behavioural pharmacology op ‘D-1-like’ dopamine receptors: Further subtyping, new pharmacological probes and interactions with ‘D-2-like’ receptors

1995 • 100 citations

Evaluation ofd-amphetamine effects on the binding of dopamine D-2 receptor radioligand,18F-fallypride in nonhuman primates using positron emission tomography

1997 • 85 citations

Amphetamine enhances extracellular concentrations of dopamine and acetylcholine in dorsolateral striatum and nucleus accumbens of freely moving rats

1992 • 39 citations

Differential effects of reserpine and tetrabenazine on rat striatal synaptosomal dopamine biosynthesis and synaptosomal dopamine pools.

1977 • 38 citations

Time‐course of modifications elicited by reserpine on the density and mRNA synthesis of the vesicular monoamine transporter, and on the density of the membrane dopamine uptake complex

1995 • 28 citations

Regional cerebral blood flow in a case of amphetamine intoxication

1980 • 21 citations

Indirect sympathomimetics and cerebral blood flow and metabolism.

1977 • 6 citations