Striatal binding of the PET ligand ¹¹C‐raclopride is altered by drugs that modify synaptic dopamine levels

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1990 • 2,630 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-¹¹C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

1990 • 1,412 citations

Positron Emission Tomography Reveals Elevated D ₂ Dopamine Receptors in Drug-Naive Schizophrenics

1986 • 935 citations

Dopamine receptors and the dopamine hypothesis of schizophrenia

1987 • 867 citations

The Dopamine Hypothesis of Schizophrenia: A Review*

1976 • 862 citations

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

1991 • 859 citations

Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

1986 • 847 citations

A direct comparison of amphetamine-induced behaviours and regional brain dopamine release in the rat using intracerebral dialysis

1987 • 404 citations

Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis

1989 • 402 citations

Compartmental Analysis of [¹¹C]Flumazenil Kinetics for the Estimation of Ligand Transport Rate and Receptor Distribution Using Positron Emission Tomography

1991 • 344 citations

The dopamine uptake inhibitor GBR 12909: selectivity and molecular mechanism of action

1989 • 343 citations

Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress

1990 • 308 citations

Endogenous dopamine lowers the dopamine D₂ receptor density as measured by [³H]raclopride: Implications for positron emission tomography of the human brain

1989 • 298 citations

Amphetamine‐Induced Dopamine Release in the Rat Striatum: An In Vivo Microdialysis Study

1988 • 291 citations

Brain reward systems and abuse

1988 • 274 citations

Distribution of D2 dopamine receptor mRNA in rat brain.

1989 • 263 citations

Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: Specific inhibitors of dopamine uptake

1984 • 233 citations

GABAergic inhibition of endogenous dopamine release measured in vivo with 11C-raclopride and positron emission tomography

1992 • 211 citations

The incidence of cancer in schizophrenic patients.

1989 • 175 citations

In vivo characterization of locally applied dopamine uptake inhibitors by striatal microdialysis

1990 • 159 citations

Amphetamine‐stimulated dopamine release competes in vivo for [¹²³I]IBZM binding to the D2 receptor in nonhuman primates

1992 • 157 citations

GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine

1991 • 123 citations

Effects of endogenous dopamine on kinetics of [³H]N‐methylspiperone and [³H]raclopride binding in the rat brain

1991 • 122 citations

Effects of endogenous dopamine on measures of [¹⁸F]N‐methylspiroperidol binding in the basal ganglia: Comparison of simulations and experimental results from PET studies in baboons

1991 • 105 citations

Differentiation of Radioligand Delivery and Binding in the Brain: Validation of a Two-Compartment Model for [¹¹C]Flumazenil

1991 • 94 citations

Amphetamine induced decreases in (¹⁸F)‐N‐methylspiroperidol binding in the baboon brain using positron emission tomography (PET)

1991 • 91 citations

Kinetic properties of the accumulation of 3H-raclopride in the mouse brain in vivo

1989 • 79 citations

Tetrabenazine has properties of a dopamine receptor antagonist

1982 • 61 citations

Positron emission tomography (PET) studies of dopaminergic/cholinergic interaction in the baboon brain

1990 • 53 citations

In vivo binding of [11C]tetrabenazine to vesicular monoamine transporters in mouse brain

1992 • 50 citations

Quantitation of the human basal ganglia with positron emission tomography: a phantom study of the effect of contrast and axial positioning

1991 • 46 citations

Decreased in vivo binding to brain benzodiazepine receptors during social isolation

1989 • 39 citations

Modulation by dopamine of [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3h]btcp, a phencyclidine derivative) binding to the dopamine uptake complex

1991 • 38 citations

Serotonin Agonists Reduce Dopamine Synthesis in the Striatum Only when the Impulse Flow of Nigro‐Striatal Neurons Is Intact

1985 • 37 citations

Neurochemical changes following the administration of depleters of biogenic monoamines

1976 • 37 citations

In vivo microdialysis and thermospray tandem mass spectrometry of the dopamine uptake blocker 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR-12909)

1990 • 35 citations

Difference in in vivo receptor binding between [3 H]N-methylspiperone and [3 H]raclopride in reserpine-treated mouse brain

1991 • 31 citations

Swim stress alters in vivo binding of [3H]N-methylspiperone

1991 • 8 citations