Sensitization of MHC class I-restricted T cells to exogenous proteins: evidence for an alternative class I-restricted antigen presentation pathway.

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

1995 • 882 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages.

1993 • 592 citations

Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

1990 • 479 citations

Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts

1983 • 445 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments

1990 • 254 citations

Inhibition of receptor-mediated but not fluid-phase endocytosis in polymorphonuclear leukocytes.

1985 • 225 citations

Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization.

1989 • 220 citations

Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues.

1994 • 216 citations

Cytotoxic T lymphocytes against a soluble protein

1987 • 178 citations

Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route.

1991 • 174 citations

Proteolytic processing of ovalbumin and beta-galactosidase by the proteasome to a yield antigenic peptides.

1994 • 172 citations

Immunization with soluble hepatitis B virus surface protein elicits murine H-2 class I-restricted CD8+ cytotoxic T lymphocyte responses in vivo.

1994 • 165 citations

Proteolytic processing of ovalbumin and beta-galactosidase by the proteasome to a yield antigenic peptides.

1994 • 160 citations

Dissociation of β2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface

1991 • 132 citations

Peptide and beta 2-microglobulin regulation of cell surface MHC class I conformation and expression.

1992 • 128 citations

Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif.

1993 • 107 citations

Vaccination of class I major histocompatibility complex (MHC)-restricted murine CD8+ cytotoxic T lymphocytes towards soluble antigens: immunostimulating-ovalbumin complexes enter the class I MHC-restricted antigen pathway and allow sensitization against the immunodominant peptide

1991 • 97 citations

Prelysosomal and lysosomal connections between autophagy and endocytosis

1992 • 81 citations

Vaccination with immunodominant peptides encapsulated in Quil A-containing liposomes induces peptide-specific primary CD8+ cytotoxic T cells

1994 • 80 citations

Prolonged survival of thymoma-bearing mice after vaccination with a soluble protein antigen entrapped in liposomes: a model study.

1992 • 78 citations

Peptide transporter‐independent, stress protein‐mediated endosomal processing of endogenous protein antigens for major histocompatibility complex class I presentation

1994 • 73 citations

Endocytosis of the class I major histocompatibility antigen via a phorbol myristate acetate-inducible pathway is a cell-specific phenomenon and requires the cytoplasmic domain [published erratum appears in J Cell Biol 1989 Sep;109(3):1381]

1989 • 62 citations

Endocytosis and dissociation of class I MHC molecules labeled with fluorescent beta-2 microglobulin.

1991 • 60 citations

Major histocompatibility complex class I‐binding peptides are recycled to the cell surface after internalization

1993 • 52 citations

Immunization with soluble simian virus 40 large T antigen induces a specific response of CD3⁺ CD4⁻ CD8⁺ cytotoxic T lymphocytes in mice

1992 • 42 citations

Class I restricted CTL recognition of a soluble protein delivered by liposomes containing lipophilic polylysines

1992 • 36 citations

CD8+ T lymphocyte-mediated antiviral immunity in mice as a result of injection of recombinant viral proteins.

1994 • 28 citations

Carrier‐mediated uptake and presentation of a major histocompatibility complex class I‐restricted peptide

1993 • 25 citations

Newly synthesized class II MHC chains are required for VSV G presentation to CTL clones

1992 • 6 citations