Carrier‐mediated uptake and presentation of a major histocompatibility complex class I‐restricted peptide

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Sequence analysis of peptides bound to MHC class II molecules

1991 • 1,071 citations

An enzyme-release assay for natural cytotoxicity

1983 • 1,063 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Phagocytic processing of bacterial antigens for class I MHC presentation to T cells

1993 • 625 citations

Proteolysis, proteasomes and antigen presentation

1992 • 576 citations

Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.

1982 • 576 citations

Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.

1986 • 513 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

1990 • 479 citations

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

1990 • 445 citations

A molecular model of MHC class-I-restricted antigen processing

1992 • 438 citations

Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2

1987 • 429 citations

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1991 • 394 citations

Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens.

1990 • 383 citations

Multiple targets for brefeldin A

1991 • 347 citations

Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

1990 • 340 citations

Presentation of Exogenous Antigen with Class I Major Histocompatibility Complex Molecules

1990 • 338 citations

Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

1991 • 336 citations

Brefeldin A Specifically Inhibits Presentation of Protein Antigens to Cytotoxic T Lymphocytes

1989 • 329 citations

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

1992 • 322 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

1988 • 294 citations

On the complexity of self

1991 • 261 citations

Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro.

1989 • 260 citations

Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells.

1985 • 229 citations

Intracellular transport of MHC class II molecules

1992 • 222 citations

Peptide-induced conformational change of the class I heavy chain

1991 • 221 citations

The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2.

1991 • 214 citations

Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi

1992 • 208 citations

Defective Presentation of Endogenous Antigen by a Cell Line Expressing Class I Molecules

1990 • 202 citations

Proteasomes are regulated by interferon gamma: implications for antigen processing.

1992 • 177 citations

MHC molecules as peptide receptors

1993 • 169 citations

Cell biology of antigen presentation

1993 • 166 citations

Effects of different transferrin forms on transferrin receptor expression, iron uptake, and cellular proliferation of human leukemic HL60 cells. Mechanisms responsible for the specific cytotoxicity of transferrin-gallium.

1986 • 138 citations

Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis.

1985 • 135 citations

The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation.

1992 • 125 citations

pH sensitive liposomes provide an efficient means of sensitizing target cells to class I restricted CTL recognition of a soluble protein

1991 • 114 citations

Recognition of pre-processed endogenous antigen by class I but not class II MHC-restricted T cells

1989 • 113 citations

Extracellular processing of peptide antigens that bind class I major histocompatibility molecules.

1992 • 107 citations

Presentation of endogenous peptides to MHC class I-restricted cytotoxic T lymphocytes in transport deletion mutant T2 cells.

1993 • 95 citations

Acetaminophen toxicity in human lymphocytes in vitro.

1980 • 87 citations

Transferrin receptors recycle to cis and middle as well as trans Golgi cisternae in Ig-secreting myeloma cells.

1986 • 86 citations

Self-peptide released from class II HLA-DR1 exhibits a hydrophobic two-residue contact motif.

1992 • 85 citations

Class I-restricted presentation occurs without internalization or processing of exogenous antigenic peptides.

1989 • 66 citations

Enhanced T cell responses to antigenic peptides targeted to B cell surface Ig, Ia, or class I molecules.

1988 • 54 citations

Exogenous antigens internalized through transferrin receptors activate CD4+ T cells.

1993 • 36 citations

Discrimination of human CD4 T cell clones based on their reactivity with antigen‐presenting T cells

1992 • 28 citations

Modulation of lymphocyte proliferation and immunoglobulin production by transferrin-gallium.

1989 • 21 citations

Effects of transferrin-indium on cellular proliferation of a human leukemia cell line.

1989 • 20 citations

Soluble HLA-A2.1 restricted peptides that are recognized by influenza virus specific cytotoxic T lymphocytes

1991 • 20 citations

Use of antibody/peptide constructs to direct antigenic peptides to T cells: Evidence for T cell processing and presentation

1992 • 20 citations