Immunization with soluble simian virus 40 large T antigen induces a specific response of CD3⁺ CD4⁻ CD8⁺ cytotoxic T lymphocytes in mice

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.

1989 • 2,118 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

1976 • 951 citations

In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine

1989 • 632 citations

Receptor-Mediated Antigen Uptake and its Effect on Antigen Presentation to Class II-Restricted T Lymphocytes

1990 • 605 citations

Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs

1990 • 479 citations

Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens

1980 • 430 citations

Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo.

1990 • 414 citations

The Cell Biology of Antigen Processing and Presentation

1991 • 349 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells

1987 • 304 citations

Class II MHC molecules can use the endogenous pathway of antigen presentation

1990 • 271 citations

MHC class II—Restricted presentation of intracellular antigen

1991 • 260 citations

Functional analysis of T lymphocyte subsets in antiviral host defense.

1987 • 237 citations

Different Roles for L3T4+ and Lyt 2+ T Cell Subsets in the Control of an Acute Herpes Simplex Virus Infection of the Skin and Nervous System

1987 • 236 citations

B-lymphoma cells process and present their endogenous immunoglobulin to major histocompatibility complex-restricted T cells.

1989 • 228 citations

Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization.

1989 • 220 citations

Cells Process Exogenous Proteins for Recognition by Cytotoxic T Lymphocytes

1988 • 217 citations

Selective killing of hepatitis B envelope antigen-specific B cells by class I-restricted, exogenous antigen-specific T lymphocytes

1990 • 208 citations

Fundamental Immunology

1990 • 207 citations

An endogenous processing pathway in vaccinia virus-infected cells for presentation of cytoplasmic antigens to class II-restricted T cells.

1990 • 188 citations

Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigen.

1988 • 180 citations

Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route.

1991 • 174 citations

Transplantable mouse tumor line induced by injection of SV40‐transformed mouse kidney cells

1969 • 173 citations

Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen

1984 • 163 citations

Antigenic binding sites of monoclonal antibodies specific for simian virus 40 large T antigen

1986 • 135 citations

Immunology 2nd ed.

1990 • 129 citations

Adjuvant-free IgG responses induced with antigen coupled to antibodies against class II MHC

1987 • 125 citations

Genetic Control of the Cytotoxic T Cell Response to SV40 Tumor-Associated Specific Antigen

1979 • 116 citations

Analysis of T-cell subsets in rejection of Kb mutant skin allografts differing at class I MHC

1986 • 114 citations

Antigen Processing for Presentation to T Lymphocytes: Function, Mechanisms, and Implications for the T-Cell Repertoire

1988 • 105 citations

A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth

1986 • 101 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg)

1980 • 99 citations

Vaccination of class I major histocompatibility complex (MHC)-restricted murine CD8+ cytotoxic T lymphocytes towards soluble antigens: immunostimulating-ovalbumin complexes enter the class I MHC-restricted antigen pathway and allow sensitization against the immunodominant peptide

1991 • 97 citations

H-2 antigen requirements in the in vitro induction of SV40-specific cytotoxic T lymphocytes.

1980 • 86 citations

Enhancement of antigenic potency in vitro and immunogenicity in vivo by coupling the antigen to anti-immunoglobulin.

1986 • 85 citations

Recognition by cytotoxic T lymphocytes of cells expressing fragments of the SV40 tumor antigen.

1983 • 81 citations

The simian virus 40 large tumor antigen

1987 • 81 citations

Demonstration of multiple antigenic sites of the SV40 transplantation rejection antigen by using cytotoxic T lymphocyte clones.

1983 • 65 citations

Role of lymphokine-secreting CD8+ T cells in cytotoxic T lymphocyte responses against vaccinia virus.

1989 • 63 citations

Class I MHC can present an endogenous peptide to cytotoxic T lymphocytes.

1989 • 62 citations

Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.

1988 • 58 citations

Mapping of H–2 genes associated with T cell-mediated cytotoxic responses to SV40–tumour-associated specific antigens

1978 • 57 citations

Capacity of purified Lyt-2+ T cells to mount primary proliferative and cytotoxic responses to Ia− tumour cells

1986 • 56 citations

Cytotoxic T cells both produce and respond to interleukin 2

1984 • 55 citations

A 15 amino acid fragment of influenza nucleoprotein synthesized in the cytoplasm is presented to class I-restricted cytotoxic T lymphocytes.

1989 • 51 citations

Localization of an immunorecessive epitope on SV40 T antigen by H-2Db-restricted cytotoxic T-lymphocyte clones and a synthetic peptide

1989 • 50 citations

The role of CD4+ cells in sustaining lymphocyte proliferation during lymphocytic choriomeningitis virus infection.

1991 • 48 citations

Specific interaction of simian virus 40 large T antigen with cellular chromatin and nuclear matrix during the course of infection

1987 • 46 citations

Autonomously proliferating K/D‐restricted cytolytic T cell clones

1983 • 44 citations

Development of autoreactive L3T4⁺ T cells from double‐negative (L3T4⁻/Ly‐2⁻) Thy‐1⁺ spleen cells of normal mice

1988 • 37 citations

T cell recognition of endogenous IgG_2a expressed in B lymphoma cells

1988 • 31 citations

Class II‐restricted IgG2a^b‐specific T cells recognize a signal‐minus form of the V‐CH3^b antigen

1991 • 22 citations

IMMUNOSUPPRESSION BY ANTI-CD4 TREATMENT IN VIVO PERSISTENCE OF SECONDARY ANTIVIRAL IMMUNE RESPONSES

1989 • 18 citations

Localization of common cytotoxic T lymphocyte recognition epitopes on Simian papovavirus sv40 and human papovavirus JC virus T antigens

1991 • 18 citations

The Development of Biosynthetic Vaccines

1989 • 8 citations

Specificity repertoire of splenic Lyt-2+/F23+ cytotoxic lymphocyte precursors from B6 mice

1987 • 1 citations