Pre-Steady-State Kinetics of the Microtubule.cntdot.Kinesin ATPase

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

A simplified method for the quantitative assay of small amounts of protein in biologic material

1973 • 1,802 citations

Mechanism of adenosine triphosphate hydrolysis by actomyosin

1971 • 1,289 citations

Bead movement by single kinesin molecules studied with optical tweezers

1990 • 1,018 citations

Movement of microtubules by single kinesin molecules

1989 • 878 citations

A novel brain ATPase with properties expected for the fast axonal transport motor

1985 • 604 citations

Analysis of numerical methods for computer simulation of kinetic processes: Development of KINSIM—A flexible, portable system

1983 • 597 citations

Muscle Contraction and Free Energy Transduction in Biological Systems

1985 • 446 citations

Microtubule-associated proteins and the stimulation of tubulin assembly in vitro

1976 • 434 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

Reversal of the cross‐bridge force‐generating transition by photogeneration of phosphate in rabbit psoas muscle fibres.

1992 • 361 citations

Intracellular Transport Using Microtubule-Based Motors

1987 • 356 citations

Phosphate Release and Force Generation in Skeletal Muscle Fibers

1985 • 324 citations

Kinesin family in murine central nervous system.

1992 • 310 citations

Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle

1985 • 301 citations

Mechanism of the actomyosin adenosine triphosphatase. Evidence that adenosine 5'-triphosphate hydrolysis can occur without dissociation of the actomyosin complex

1979 • 243 citations

Transient state phosphate production in the hydrolysis of nucleoside triphosphates by myosin

1970 • 241 citations

RELATIONSHIPS BETWEEN CHEMICAL AND MECHANICAL EVENTS DURING MUSCULAR CONTRACTION

1986 • 241 citations

Kinesin ATPase: rate-limiting ADP release.

1988 • 238 citations

Evidence that the Head of Kinesin Is Sufficient for Force Generation and Motility in Vitro

1990 • 225 citations

Pathway of the Microtubule-Dynein ATPase and the Structure of Dynein: A Comparison with Actomyosin

1985 • 215 citations

Kinetics of the Actomyosin ATPase in Muscle Fibers

1987 • 190 citations

Quantized velocities at low myosin densities in an in vitro motility

1991 • 182 citations

Exchange between inorganic phosphate and adenosine 5'-triphosphate in the medium by actomyosin subfragment 1

1980 • 177 citations

Kinesin undergoes a 9 S to 6 S conformational transition.

1992 • 169 citations

Elementary processes of the magnesium ion-dependent adenosine triphosphatase activity of heavy meromysin. A transient kinetic approach to the study of kinases and adenosine triphosphatases and a colorimetric inorganic phosphate assay in situ

1972 • 165 citations

Molecular evolution of the myosin family: relationships derived from comparisons of amino acid sequences.

1993 • 164 citations

[61] Rapid kinetic analysis of mechanochemical adenosinetriphosphatases

1986 • 151 citations

Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein.

1993 • 140 citations

Kinetics of the interaction of 2'(3')-O-(N-methylanthraniloyl)-ATP with myosin subfragment 1 and actomyosin subfragment 1: Characterization of two acto.cntdot.S1.cntdot.ADP complexes

1991 • 132 citations

A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics

1988 • 130 citations

Effects of Kinesin Mutations on Neuronal Functions

1992 • 117 citations

Kinetic studies on the association and dissociation of myosin subfragment 1 and actin.

1991 • 112 citations

Cytoplasmic microtubule-based motor proteins

1993 • 106 citations

Chemomechanical cycle of kinesin differs from that of myosin

1993 • 105 citations

The kinesin superfamily: tails of functional redundancy

1991 • 103 citations

Oxygen exchange between Pi in the medium and water during ATP hydrolysis mediated by skinned fibers from rabbit skeletal muscle. Evidence for Pi binding to a force-generating state.

1986 • 97 citations

Isolation and characterization of the gene encoding the heavy chain of Drosophila kinesin.

1988 • 92 citations

Activation of the dynein adenosinetriphosphatase by microtubules. Kinetics of ATP-induced dissociation and re-formation of the microtubule-dynein complex

1986 • 92 citations

Identification and partial characterization of six members of the kinesin superfamily in Drosophila.

1991 • 90 citations

Expression, purification, and characterization of the Drosophila kinesin motor domain produced in Escherichia coli

1993 • 88 citations

The pathway of ATP hydrolysis by dynein. Kinetics of a presteady state phosphate burst.

1983 • 82 citations

Transient state kinetic analysis of the ATP-induced dissociation of the dynein-microtubule complex.

1983 • 80 citations

Genetic Approaches to Molecular Motors

1992 • 80 citations

Decoration of the microtubule surface by one kinesin head per tubulin heterodimer

1993 • 79 citations

Characterization of α2β2 and α2 forms of kinesin

1991 • 77 citations

A kinetic study of the kinesin ATPase.

1992 • 72 citations

Microtubules accelerate ADP release by dynein

1989 • 58 citations

ADP release is rate limiting in steady state turnover by the dynein adenosinetriphosphatase

1989 • 50 citations

Nucleotide-free Kinesin Hydrolyzes ATP with Burst Kinetics

1989 • 40 citations

Effect of actin concentration on the intermediate oxygen exchange of myosin; relation to the refractory state and the mechanism of exchange

1978 • 37 citations

Catalytic consequences of oligomeric organization: kinetic evidence for "tethered" acto-heavy meromyosin at low ATP concentrations.

1984 • 25 citations

The rate of ATP synthesis by dynein

1986 • 23 citations

The actomyosin ATPase: a two-state system

1992 • 20 citations

Kinesin and myosin ATPases: variations on a theme

1992 • 5 citations