Complementation between two cell lines lacking kappa enhancer activity: implications for the developmental control of immunoglobulin transcription.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1985 • 1,155 citations

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

1986 • 1,150 citations

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

1984 • 889 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Enhancer elements

1983 • 576 citations

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

1986 • 558 citations

A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene

1984 • 410 citations

The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells

1978 • 324 citations

The role of the κ enhancer and its binding factor NF-κB in the developmental regulation of κ gene transcription

1987 • 247 citations

Transcription of the unrearranged mouse Cκ locus: Sequence of the initiation region and comparison of activity with a rearranged Vκ-Cκ gene

1981 • 190 citations

Differentiation-dependent chromatin alterations precede and accompany transcription of immunoglobulin light chain genes.

1984 • 167 citations

Enhancers: Mechanisms of Action and Cell Specificity

1988 • 159 citations

Fine mapping of an immunoglobulin gene activator.

1984 • 144 citations

[28] Cell fusion

1979 • 141 citations

Chromatin changes accompany immunoglobulin κ gene activation: a potential control region within the gene

1982 • 138 citations

Expression of immunoglobulin heavy chain at a high level in the absence of a proposed immunoglobulin enhancer element in cis.

1984 • 135 citations

Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant.

1984 • 127 citations

The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.

1988 • 96 citations

Deletion of a B-cell-specific enhancer affects transfected, but not endogenous, immunoglobulin heavy-chain gene expression.

1985 • 92 citations

Structure of a nuclease-sensitive region inside the immunoglobin kappa gene: evidence for a role in gene regulation

1983 • 92 citations

Independent immunoglobulin class-switch events occurring in a single myeloma cell line.

1985 • 81 citations

Inducible transcription of the unrearranged kappa constant region locus is a common feature of pre-B cells and does not require DNA or protein synthesis.

1985 • 79 citations

Lipopolysaccharide-induced transcription of the kappa immunoglobulin locus occurs on both alleles and is independent of methylatlon status

1984 • 65 citations

Transcription termination and chromatin structure of the active immunoglobulin kappa gene locus.

1986 • 54 citations

Tandem kappa immunoglobulin promoters are equally active in the presence of the kappa enhancer: Implications for models of enhancer function

1986 • 47 citations

Evidence for transient requirement of the IgH enhancer

1985 • 46 citations

The Coupling Between Enhancer Activity and Hypomethylation of κ Immunoglobulin Genes is Developmentally Regulated

1988 • 36 citations

Induction of kappa light chain synthesis in 70Z/3 B lymphoma cells by chemically defined lipid A precursors.

1988 • 34 citations

Independent Immunoglobulin Class-Switch Events Occurring in a Single Myeloma Cell Line

1985 • 32 citations