Polyadenylation precedes splicing in vitro.

Exon definition may facilitate splice site selection in RNAs with multiple exons.

1990 • 726 citations

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.

1988 • 539 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs

1986 • 490 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Accurate cleavage and polyadenylation of exogenous RNA substrate

1985 • 334 citations

In vitro polyadenylation is stimulated by the presence of an upstream intron.

1990 • 313 citations

Definition of an efficient synthetic poly(A) site.

1989 • 285 citations

The stem-loop structure at the 3' end of histone mRNA is necessary and sufficient for regulation of histone mRNA stability.

1987 • 238 citations

3′ cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP

1988 • 205 citations

Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation

1988 • 195 citations

Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles.

1988 • 183 citations

Presplicing complex formation requires two proteins and U2 snRNP.

1988 • 117 citations

Multiple factors are required for specific RNA cleavage at a poly(A) addition site.

1988 • 106 citations

Structure of late adenovirus 2 heterogeneous nuclear RNA

1979 • 86 citations

Introns in histone genes alter the distribution of 3′ ends

1990 • 73 citations

Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs.

1987 • 64 citations

Splice site selection dominates over poly(A) site choice in RNA production from complex adenovirus transcription units.

1988 • 64 citations

Specific pre-cleavage and post-cleavage complexes involved in the formation of SV40 late mRNA 3′ termini in vitro.

1987 • 57 citations

Competition between splicing and polyadenylation reactions determines which adenovirus region E3 mRNAs are synthesized.

1988 • 42 citations

In vitro cleavage of the simian virus 40 early polyadenylation site adjacent to a required downstream TG sequence.

1986 • 36 citations

A Splice Junction Deletion Deficient in the Transport of RNA Does Not Polyadenylate Nuclear RNA

1983 • 34 citations