Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs.

FINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE

1967 • 2,534 citations

JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN

1969 • 2,408 citations

A cell culture model of the blood-brain barrier.

1991 • 753 citations

Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

1983 • 737 citations

Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization.

1990 • 581 citations

Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard

1970 • 546 citations

An in situ brain perfusion technique to study cerebrovascular transport in the rat

1984 • 538 citations

High‐ and Low‐Affinity Transport of D‐Glucose from Blood to Brain

1981 • 325 citations

Bidirectional transport of interleukin-1 alpha across the blood-brain barrier

1989 • 323 citations

Peptide Drug Delivery to the Brain

1992 • 309 citations

Peptides and the blood-brain barrier: Lipophilicity as a predictor of permeability

1985 • 297 citations

Drug Transfer Across the Blood‐Brain Barrier: Correlation Between In Vitro and In Vivo Models

1992 • 289 citations

The use of cultured epithelial and endothelial cells for drug transport and metabolism studies.

1990 • 272 citations

Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier.

1990 • 263 citations

Neutral metalloendopeptidase in human lung tissue and cultured cells.

1985 • 259 citations

Entry of Opioid Peptides into the Central Nervous System

1980 • 247 citations

Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism.

1986 • 246 citations

Bovine Brain Endothelial Cells Express Tight Junctions and Monoamine Oxidase Activity in Long‐Term Culture

1989 • 210 citations

Bovine Brain Microvessel Endothelial Cell Monolayers as a Model System for the Blood‐Brain Barriera

1987 • 177 citations

Peptide transport systems for opiates across the blood-brain barrier

1990 • 140 citations

Distribution of enkephalinase (membrane metalloendopeptidase, E.C. 3.4.24.11) in rat organs. Detection using a monoclonal antibody.

1988 • 120 citations

Permeability of the blood-cerebrospinal fluid and blood-brain barriers to thyrotropin-releasing hormone

1985 • 93 citations

Drug Delivery to the Brain by Blood-Brain Barrier Circumvention and Drug Modification

1989 • 76 citations

Whole body and brain distribution of [3H]cyclic [D-Pen2,D-Pen5] enkephalin after intraperitoneal, intravenous, oral and subcutaneous administration.

1992 • 73 citations

Assessment of Transport Barriers Using Cell and Tissue Culture Systems

1990 • 16 citations

Methods of Measuring Neuropeptides and Their Metabolism

1991 • 12 citations