Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier.

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

The theory and applications of the exchange of inert gas at the lungs and tissues.

1951 • 1,620 citations

The Permeability of Capillaries in Various Organs as Determined by Use of the ‘Indicator Diffusion’ Method

1963 • 1,138 citations

The Concept of a Blood-Brain Barrier

1980 • 812 citations

Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles

1959 • 717 citations

An in situ brain perfusion technique to study cerebrovascular transport in the rat

1984 • 538 citations

Receptor‐mediated transcytosis of transferrin across the blood‐brain barrier

1987 • 523 citations

Tight junctions of brain endothelium in vitro are enhanced by astroglia

1987 • 389 citations

Lipid Solubility and Drug Penetration of the Blood Brain Barrier

1974 • 372 citations

Morphology of blood-brain interfaces

1977 • 300 citations

Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs.

1988 • 139 citations

Characteristics of the Large Neutral Amino Acid Transport System of Bovine Brain Microvessel Endothelial Cell Monolayers

1986 • 122 citations

Microvascular endothelium and pericytes: High yield, low passage cultures

1986 • 107 citations

Rat brain regional uptake and decarboxylation of L-DOPA following carotid injection

1975 • 86 citations

Estimates of Michaelis-Menten Constants for the Two Membranes of the Brain Endothelium

1984 • 84 citations

The application of bovine brain microvessel endothelial-cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier.

1989 • 79 citations

Absence of albumin receptor on brain capillaries in vivo or in vitro

1985 • 78 citations

Antibodies to Blood—Brain Barrier Bind Selectively to Brain Capillary Endothelial Lateral Membranes and to a 46K Protein

1986 • 52 citations

cDNA Cloning and Sequence Analysis of the Glucose Transporter from Porcine Blood-Brain Barrier

1989 • 51 citations

Clearance of 3‐methoxy‐4‐hydroxyphenylglycol from the cerebrospinal fluid

1976 • 25 citations

Monoamine Oxidase Activity in the Cerebral Vasculature: Comparison between Fresh Microvessels from Different Structures and Cell Cultures Derived from Microvessels

1984 • 11 citations

Morphological alterations in cultured endothelial cells induced by arachidonic acid

1985 • 10 citations