Activation and proliferation signals in murine macrophages. Biochemical signals controlling the regulation of macrophage urokinase-type plasminogen activator activity by colony-stimulating factors and other agents

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

A study of proteases and protease-inhibitor complexes in biological fluids

1978 • 810 citations

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

1982 • 671 citations

Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor.

1983 • 568 citations

The Hemopoietic Colony-stimulating Factors

1995 • 565 citations

Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors.

1986 • 532 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

Amiloride selectively inhibits the urokinase‐type plasminogen activator

1987 • 378 citations

Induction of c-fos during myelomonocytic differentiation and macrophage proliferation

1985 • 340 citations

Hierarchical down-modulation of hemopoietic growth factor receptors

1985 • 314 citations

Purification and characterization of a plasminogen activator inhibitor from the histiocytic lymphoma cell line U-937.

1986 • 249 citations

Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages.

1989 • 242 citations

Macrophage plasminogen activator: induction by concanavalin A and phorbol myristate acetate

1977 • 241 citations

[42] The macrophage colony-stimulating factor, CSF-1

1985 • 232 citations

Macrophage fibrinolytic activity: Identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor

1982 • 225 citations

Stimulation of macrophage plasminogen activator activity by colony‐stimulating factors

1980 • 223 citations

The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF‐1

1985 • 178 citations

THE ROLE OF CYCLIC AMP IN CELL PROLIFERATION: A CRITICAL ASSESSMENT OF THE EVIDENCE

1983 • 165 citations

Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor

1978 • 161 citations

The de novo phospholipid effect of insulin is associated with increases in diacylglycerol, but not inositol phosphates or cytosolic Ca2+

1985 • 146 citations

Macrophage plasminogen activator: induction by products of activated lymphoid cells.

1977 • 141 citations

Identification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1.

1988 • 110 citations

Interleukin 3 binds to a 140-kDa phosphotyrosine-containing cell surface protein.

1988 • 104 citations

Stimulation of human synovial fibroblast plasminogen activator production by mononuclear cell supernatants.

1981 • 101 citations

Purification of two forms of colony-stimulating factor from mouse L-cell-conditioned medium.

1985 • 90 citations

The haemopoietic growth factors interleukin 3 and colony stimulating factor-1 stimulate proliferation but do not induce inositol lipid breakdown in murine bone-marrow-derived macrophages.

1986 • 90 citations

Activation and proliferation signals in murine macrophages: Stimulation of glucose uptake by hemopoietic growth factors and other agents

1988 • 87 citations

Colony-stimulating factor 1 activates protein kinase C in human monocytes.

1990 • 87 citations

Suppression of urokinase-type plasminogen activator mRNA levels in human fibrosarcoma cells and synovial fibroblasts by anti-inflammatory glucocorticoids.

1986 • 85 citations

Modulation of urokinase plasminogen activator gene expression during the transition from quiescent to proliferative state in normal mouse cells.

1986 • 83 citations

Inhibition of macrophage activation by calcium channel blockers and calmodulin antagonists

1985 • 82 citations

Activation and proliferation signals in murine macrophages: Stimulation of Na⁺, K⁺‐ATPase activity by hemopoietic growth factors and other agents

1988 • 82 citations

Inhibition of the signaling pathways for macrophage proliferation by cyclic AMP. Lack of effect on early responses to colony stimulating factor-1.

1990 • 79 citations

Modulations of functional activity in differentiated macrophages are accompanied by early and transient increase or decrease in c-fos gene transcription.

1987 • 77 citations

CSF-1 stimulates Na+K+-ATPase mediated 86Rb+ uptake in mouse bone marrow-derived macrophages

1985 • 74 citations

Lymphokine‐induced secretion of plasminogen activator by murine macrophages

1977 • 74 citations

Colony-stimulating factor 1-induced Na+ influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein.

1988 • 69 citations

Trypanosoma cruzi: the immunological induction of macrophage plasminogen activator requires thymus-derived lymphocytes.

1977 • 61 citations

The correlation between plasminogen activator activity and thymidine incorporation in mouse bone marrow-derived macrophages

1984 • 50 citations

Activation of human monocytes by granulocyte-macrophage colony- stimulating factor: increased urokinase-type plasminogen activator activity

1991 • 46 citations

Na+/H+ exchange involvement in colony-stimulating factor-1-stimulated macrophage proliferation. Evidence for a requirement during late G1 of the cell cycle but not for early growth factor responses.

1990 • 43 citations

Human synovial fibroblast plasminogen activator. modulation of enzyme activity by antiinflammatory steroids

1981 • 42 citations

Inhibition of interleukin 3 and colony-stimulating factor 1-stimulated marrow cell proliferation by pertussis toxin

1988 • 42 citations

Divergent disease patterns in granulocyte-macrophage colony-stimulating factor transgenic mice associated with different transgene insertion sites.

1988 • 39 citations

Induction of Macrophage DNA Synthesis by phorbol esters

1981 • 36 citations

Regulation of proliferation of bone marrow-derived macrophages.

1987 • 35 citations

Activation and proliferation signals in murine macrophages: Relationships among c‐fos and c‐myc expression, phosphoinositide hydrolysis, superoxide formation, and DNA synthesis

1989 • 34 citations

Activation and proliferation signals in murine macrophages: synergistic interactions between the hematopoietic growth factors and with phorbol ester for DNA synthesis

1988 • 29 citations

Regulation of prostaglandin and plasminogen activator production by mouse peritoneal macrophages.

1981 • 21 citations

Regulation by interleukin-3 of human monocyte pro-inflammatory mediators. Similarities with granulocyte-macrophage colony-stimulating factor.

1990 • 19 citations

Pertussigen in vivo enhances antigen-specific production in vitro of lymphokine that stimulates macrophage procoagulant activity and plasminogen activator.

1986 • 10 citations