Na+/H+ exchange involvement in colony-stimulating factor-1-stimulated macrophage proliferation. Evidence for a requirement during late G1 of the cell cycle but not for early growth factor responses.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Amiloride and its analogs as tools in the study of ion transport

1988 • 1,131 citations

Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

1989 • 749 citations

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

1982 • 671 citations

CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

1983 • 536 citations

Effects of Growth Factors on Intracellular pH Regulation

1986 • 498 citations

Hemopoietic colony-stimulating factors

1984 • 468 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

Induction of c-fos during myelomonocytic differentiation and macrophage proliferation

1985 • 340 citations

Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series.

1984 • 305 citations

Arginine vasopressin enhances pHi regulation in the presence of HCO−3 by stimulating three acid-base transport systems

1989 • 269 citations

Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages.

1989 • 242 citations

[42] The macrophage colony-stimulating factor, CSF-1

1985 • 232 citations

Fura-2 secretion and sequestration in macrophages. A blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions.

1988 • 192 citations

The regulation of mononuclear phagocyte entry into S phase by the colony stimulating factor CSF‐1

1985 • 178 citations

Characterization of potent sodium/proton exchange inhibitors from the amiloride series in A431 cells

1984 • 144 citations

Intracellular pH controls growth factor-induced ribosomal protein S6 phosphorylation and protein synthesis in the G0→G1 transition of fibroblasts

1986 • 126 citations

Extracellular Na+ and initiation of DNA synthesis: role of intracellular pH and K+.

1984 • 117 citations

Interleukin 2 induces a rapid increase in intracellular pH through activation of a Na+/H+ antiport. Cytoplasmic alkalinization is not required for lymphocyte proliferation.

1985 • 114 citations

The regulation of macrophage protein turnover by a colony stimulating factor (CSF‐1)

1983 • 97 citations

Amiloride, protein synthesis, and activation of quiescent cells

1982 • 94 citations

Mitogen‐independent activation of Na⁺/H⁺ exchange in human epidermoid carcinoma A431 cells: Regulation by medium osmolarity

1985 • 92 citations

Intracellular K+ and the mitogenic response of 3T3 cells to peptide factors in serum-free medium.

1982 • 92 citations

Purification of two forms of colony-stimulating factor from mouse L-cell-conditioned medium.

1985 • 90 citations

The haemopoietic growth factors interleukin 3 and colony stimulating factor-1 stimulate proliferation but do not induce inositol lipid breakdown in murine bone-marrow-derived macrophages.

1986 • 90 citations

Activation and proliferation signals in murine macrophages: Stimulation of glucose uptake by hemopoietic growth factors and other agents

1988 • 87 citations

Role of Na⁺/H⁺Exchange by Interferon-γ in Enhanced Expression of JE and I-A_βGenes

1989 • 83 citations

Activation and proliferation signals in murine macrophages: Stimulation of Na⁺, K⁺‐ATPase activity by hemopoietic growth factors and other agents

1988 • 82 citations

Inhibition of the signaling pathways for macrophage proliferation by cyclic AMP. Lack of effect on early responses to colony stimulating factor-1.

1990 • 79 citations

Growth factors activate the bumetanide-sensitive Na+/K+/Cl-cotransport in hamster fibroblasts.

1986 • 78 citations

CSF-1 stimulates Na+K+-ATPase mediated 86Rb+ uptake in mouse bone marrow-derived macrophages

1985 • 74 citations

Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.

1984 • 74 citations

Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells.

1988 • 71 citations

Cytoplasmic pH regulation in macrophages by an ATP-dependent and N,N′-dicyclohexylcarbodiimide-sensitive mechanism. Possible involvement of a plasma membrane proton pump.

1988 • 66 citations

Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport

1987 • 50 citations

CSF-1 stimulates glucose uptake in murine bone marrow-derived macrophages

1986 • 43 citations

Activation of Na+/H+ exchange and the expression of cellular proto-oncogenes in mitogen- and phorbol ester-treated lymphocytes.

1988 • 41 citations

Amiloride and amiloride analogs inhibit Na+/K+-transporting ATPase and Na+-coupled alanine transport in rat hepatocytes

1988 • 39 citations

Activation and proliferation signals in murine macrophages: Relationships among c‐fos and c‐myc expression, phosphoinositide hydrolysis, superoxide formation, and DNA synthesis

1989 • 34 citations

Demonstration of a late amiloride‐sensitive event as a necessary step in initiation of DNA synthesis by thrombin

1983 • 32 citations

Activation and proliferation signals in murine macrophages: synergistic interactions between the hematopoietic growth factors and with phorbol ester for DNA synthesis

1988 • 29 citations

Single‐cell analysis of the intracellular pH and its regulation during the monocytic differentiation of U937 human leukemic cells

1988 • 29 citations

Relationship among activation of the Na+/H+ antiporter, ornithine decarboxylase induction, and DNA synthesis

1987 • 29 citations

Amiloride added together with bumetanide completely blocks mouse 3T3-cell exit from G0/G1-phase and entry into S-phase

1986 • 27 citations

Effect of Na⁺ flux inhibitors on induction of c‐fos, c‐myc, and ODC genes during cell cycle

1989 • 23 citations

Control of cytoplasmic pH by Na⁺/H⁺ exchange in rat peritoneal macrophages activated with phorbol ester

1987 • 21 citations

Increase in intracellular Na+: transmembrane signal for rejoining of DNA strand breaks in proliferating lymphocytes.

1987 • 18 citations

Activation of the Na+/H+ antiport is not required for epidermal growth factor-dependent gene expression, growth inhibition or proliferation in human breast cancer cells

1989 • 12 citations

Relationship of the decreases in protein synthesis and intracellular Na+ during friend murine erythroleukemic cell differentiation.

1986 • 8 citations