Specificity and Regulation of CD18-Dependent Adhesions

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

1985 • 833 citations

Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies.

1983 • 674 citations

The effects of bacterial endotoxins on host mediation systems. A review.

1978 • 648 citations

Interleukin 1: An Immunological Perspective

1985 • 576 citations

A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo

1987 • 525 citations

Cloning of the $beta; subunit of the leukocyte adhesion proteins: Homology to an extracellular matrix receptor defines a novel supergene family

1987 • 520 citations

Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes.

1983 • 495 citations

The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester.

1986 • 487 citations

Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen.

1988 • 457 citations

Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes.

1982 • 444 citations

Membrane complement receptor type three (CR3) has lectin-like properties analogous to bovine conglutinin as functions as a receptor for zymosan and rabbit erythrocytes as well as a receptor for iC3b.

1985 • 433 citations

Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos.

1984 • 429 citations

Complete amino acid sequence of human vitronectin deduced from cDNA. Similarity of cell attachment sites in vitronectin and fibronectin.

1985 • 418 citations

Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide.

1986 • 415 citations

Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes.

1983 • 408 citations

Human neutrophils increase expression of C3bi as well as C3b receptors upon activation.

1984 • 391 citations

Neural crest cell migration: requirements for exogenous fibronectin and high cell density.

1983 • 388 citations

Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.

1987 • 370 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

Reduction of inflammation, tissue damage, and mortality in bacterial meningitis in rabbits treated with monoclonal antibodies against adhesion-promoting receptors of leukocytes.

1989 • 339 citations

Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils.

1985 • 291 citations

Transient adhesion of neutrophils to endothelium.

1989 • 279 citations

cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.

1987 • 277 citations

The role of neutrophil membrane glycoprotein GP-150 in neutrophil adherence to endothelium in vitro

1985 • 268 citations

CR3 (CD11b/CD18) expresses one binding site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide.

1989 • 264 citations

Role of the adherence-promoting receptors, CR3, LFA-1, and p150,95, in binding of Histoplasma capsulatum by human macrophages.

1987 • 259 citations

Chemoattractant-Regulated Mobilization of a Novel Intracellular Compartment in Human Neutrophils

1987 • 256 citations

Aggregation of complement receptors on human neutrophils in the absence of ligand.

1987 • 250 citations

Subcellular localization of the large subunit of Mo1 (Mo1 alpha; formerly gp 110), a surface glycoprotein associated with neutrophil adhesion.

1984 • 249 citations

An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2.

1987 • 246 citations

Complement receptor type 3 (CR3) binds to an Arg-Gly-Asp-containing region of the major surface glycoprotein, gp63, of Leishmania promastigotes.

1988 • 242 citations

Evidence that arginyl-glycyl-aspartate peptides and fibrinogen gamma chain peptides share a common binding site on platelets.

1987 • 222 citations

The primary structure of the beta-subunit of the cell surface adhesion glycoproteins LFA-1, CR3 and p150,95 and its relationship to the fibronectin receptor.

1987 • 215 citations

Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes.

1986 • 206 citations

Local opsonization by secreted macrophage complement components. Role of receptors for complement in uptake of zymosan.

1984 • 205 citations

Two functional domains in the phagocyte membrane glycoprotein Mo1 identified with monoclonal antibodies.

1986 • 174 citations

Molecular cloning of the major surface antigen of leishmania.

1988 • 169 citations

C3bi receptor (complement receptor type 3) recognizes a region of complement protein C3 containing the sequence Arg-Gly-Asp.

1987 • 163 citations

The mechanism of T cell mediated cytotoxicity II. morphological studies of cell death by time-lapse microcinematography

1976 • 146 citations

Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3).

1988 • 140 citations

Phagocytosing macrophages exclude proteins from the zones of contact with opsonized targets

1984 • 134 citations

The CD11/CD18 Leukocyte Glycoprotein Deficiency

1988 • 132 citations

Regulation of fibronectin receptor distribution by transformation, exogenous fibronectin, and synthetic peptides.

1986 • 128 citations

Ligated complement receptors do not activate the arachidonic acid cascade in resident peritoneal macrophages.

1985 • 128 citations

Elastase-mediated fibrinogenolysis by chemoattractant-stimulated neutrophils occurs in the presence of physiologic concentrations of antiproteinases.

1987 • 123 citations

Fibronectin receptor of human macrophages recognizes the sequence Arg-Gly-Asp-Ser.

1985 • 111 citations

Characterization of patients with an increased susceptibility to bacterial infections and a genetic deficiency of leukocyte membrane complement receptor type 3 and the related membrane antigen LFA-1

1985 • 98 citations

Peptides containing the cell-attachment recognition signal Arg-Gly-Asp prevent gastrulation in Drosophila embryos

1987 • 88 citations

Association between gelatinase release and increased plasma membrane expression of the Mo1 glycoprotein.

1987 • 86 citations

Interferon-gamma depresses binding of ligand by C3b and C3bi receptors on cultured human monocytes, an effect reversed by fibronectin.

1986 • 85 citations

Clustering of ligand on the surface of a particle enhances adhesion to receptor-bearing cells.

1988 • 62 citations

Adhesion-promoting receptors on phagocytes

1988 • 53 citations

C3bi受容器(3型補体受容器)によるArg‐Gly‐Asp鎖を含むC3領域の認識

1987 • 46 citations