Parental Origin of the Extra Chromosome in Trisomy 21 as Indicated by Analysis of DNA Polymorphisms

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

1977 • 1,372 citations

TRISOMY IN MAN

1984 • 652 citations

The polydeoxyadenylate tract of Alu repetitive elements is polymorphic in the human genome.

1990 • 254 citations

Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions.

1990 • 187 citations

Evidence for Reduced Recombination on the Nondisjoined Chromosomes 21 in Down Syndrome

1987 • 186 citations

Non‐disjunction in trisomy 21: study of chromosomal heteromorphisms in 110 families

1980 • 115 citations

Paris Conference (1971): Standardization in human cytogenetics.

1972 • 94 citations

Cloned DNA probes regionally mapped to human Chromosome 21 and their use in determining the origin of nondisjunction

1985 • 93 citations

Use of short sequence repeat DNA polymorphisms after PCR amplification to detect the parental origin of the additional chromosome 21 in Down syndrome.

1991 • 87 citations

Paris Conference (1971): Standardization in Human Cytogenetics

1972 • 70 citations

Use of a chromosome 21 cloned DNA probe for the analysis of non-disjunction in Down syndrome

1984 • 60 citations

Linkage analysis of the human HMG14 gene on chromosome 21 using a GT dinucleotide repeat as polymorphic marker

1990 • 60 citations

Localization of transcripts produced in vivo and in vitro on phage SP82 genome

1977 • 60 citations

Analysis of DNA haplotypes suggests a genetic predisposition to trisomy 21 associated with DNA sequences on chromosome 21.

1985 • 41 citations

Trisomy 21 (Down syndrome): studying nondisjunction and meiotic recombination by using cytogenetic and molecular polymorphisms that span chromosome 21.

1988 • 32 citations

The Christchurch Chromosome (Gp–)

1970 • 31 citations

Linkage mapping of the highly informative DNA marker D21S156 to human chromosome 21 using a polymorphic GT dinucleotide repeat

1990 • 29 citations

Down syndrome and maternal age: the effect of erroneous assignment of parental origin.

1987 • 27 citations

The use of DNA probes to establish parental origin in Down syndrome

1988 • 20 citations

The probability of detecting the origin of nondisjunction of autosomal trisomies.

1989 • 16 citations