Cloned DNA probes regionally mapped to human Chromosome 21 and their use in determining the origin of nondisjunction

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels

1977 • 1,607 citations

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

1977 • 1,372 citations

Cloning of a representative genomic library of the human X chromosome after sorting by flow cytometry

1981 • 277 citations

Analysis of chromosomal integration and deletions of yeast plasmids

1977 • 233 citations

Regional localization on the human X of DNA segments cloned from flow sorted chromosomes

1982 • 191 citations

A new method for the preparation of metaphase chromosomes for flow analysis.

1981 • 175 citations

Toward a complete linkage map of the human X chromosome: regional assignment of 16 cloned single-copy DNA sequences employing a panel of somatic cell hybrids.

1984 • 146 citations

Construction and characterization of genomic libraries from specific human chromosomes.

1982 • 142 citations

Human cytoplasmic superoxide dismutase cDNA clone: a probe for studying the molecular biology of Down syndrome.

1982 • 95 citations

Assignment of human beta-, gamma-, and delta-globin genes to the short arm of chromosome 11 by chromosome sorting and DNA restriction enzyme analysis.

1979 • 91 citations

Use of a chromosome 21 cloned DNA probe for the analysis of non-disjunction in Down syndrome

1984 • 60 citations

Chromosome sorting and DNA sequence localization

1982 • 54 citations

The 1981 catalogue of assigned human genetic markers and report of the nomenclature committee

1982 • 45 citations

Assigning the polymorphic human insulin gene to the short arm of chromosome 11 by chromosome sorting

1982 • 26 citations