Biological effects of stroma-derived factor-1α on normal and CML CD34+ haemopoietic cells

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1998 • 3,660 citations

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1998 • 2,755 citations

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1996 • 2,374 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

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1992 • 2,130 citations

Chemokines

1997 • 1,926 citations

Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4

1999 • 1,714 citations

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

1998 • 1,687 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1998 • 1,535 citations

The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

1997 • 1,414 citations

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

1997 • 1,124 citations

Molecular cloning and structure of a pre-B-cell growth-stimulating factor.

1994 • 818 citations

The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1

1998 • 642 citations

Identification and characterization of an inhibitor of haemopoietic stem cell proliferation

1990 • 470 citations

In Vitro Behavior of Hematopoietic Progenitor Cells Under the Influence of Chemoattractants: Stromal Cell–Derived Factor-1, Steel Factor, and the Bone Marrow Environment

1998 • 417 citations

IP-10, a -C-X-C- chemokine, elicits a potent thymus-dependent antitumor response in vivo.

1993 • 414 citations

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

1997 • 382 citations

Chemokine SDF-1 enhances circulating CD34+ cell proliferation in synergy with cytokines: possible role in progenitor survival

2000 • 365 citations

Chemokines: signal lamps for trafficking of T and B cells for development and effector function

1999 • 348 citations

Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin

1996 • 322 citations

Regulation of Human Chemokine Receptors CXCR4

1997 • 290 citations

Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. Interacting effects involving suppression, synergistic suppression, and blocking of suppression.

1993 • 273 citations

Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C

2000 • 266 citations

Role of C-X-C chemokines as regulators of angiogenesis in lung cancer

1995 • 250 citations

A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection

1998 • 226 citations

Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lymphohematopoietic progenitors

1999 • 188 citations

Demonstration of stem cell inhibition and myeloprotective effects of SCI/rhMIP1 alpha in vivo

1992 • 178 citations

Abnormal function of the bone marrow microenvironment in chronic myelogenous leukemia: role of malignant stromal macrophages

1995 • 175 citations

Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression

1995 • 165 citations

Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis.

1999 • 155 citations

Differential regulation of CXCR4 and CCR5 endocytosis

1998 • 146 citations

Regulation of hematopoiesis in a sea of chemokine family members with a plethora of redundant activities

1999 • 145 citations

Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)

2000 • 136 citations

The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1

1998 • 136 citations

SDF-1 Responsiveness Does Not Correlate With CXCR4 Expression Levels of Developing Human Bone Marrow B Cells

1999 • 132 citations

Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells.

1993 • 125 citations

Dissociation of the signalling and antiviral properties of SDF-1-derived small peptides

1998 • 123 citations

Involvement of Phosphatidylinositol 3-Kinase in Stromal Cell-Derived Factor-1α-Induced Lymphocyte Polarization and Chemotaxis

1999 • 122 citations

Intercellular adhesion molecule-1 mediates the expression of monocyte- derived MIP-1 alpha during monocyte-endothelial cell interactions

1994 • 119 citations

Haemopoiesis: A practical approach

1994 • 116 citations

Macrophage-inflammatory protein protects multipotent hematopoietic cells from the cytotoxic effects of hydroxyurea in vivo

1992 • 114 citations

A cell line secreting stimulating factors for CFU-GEMM culture

1984 • 113 citations

Effects of CC, CXC, C, and CX₃C Chemokines on Proliferation of Myeloid Progenitor Cells, and Insights into SDF‐1‐Induced Chemotaxis of Progenitors^a

1999 • 110 citations

TCR Activation Inhibits Chemotaxis Toward Stromal Cell-Derived Factor-1: Evidence for Reciprocal Regulation Between CXCR4 and the TCR

1999 • 105 citations

B Cell Antigen Receptor Engagement Inhibits Stromal Cell–derived Factor (SDF)-1α Chemotaxis and Promotes Protein Kinase C (PKC)-induced Internalization of CXCR4

1999 • 102 citations

Abnormal Chemokine-Induced Responses of Immature and Mature Hematopoietic Cells from Motheaten Mice Implicate the Protein Tyrosine Phosphatase Shp-1 in Chemokine Responses

1999 • 92 citations

Macrophage-inflammatory protein protects multipotent hematopoietic cells from the cytotoxic effects of hydroxyurea in vivo

1992 • 92 citations

The BCR/ABL Oncogene Alters the Chemotactic Response to Stromal-Derived Factor-1

1999 • 84 citations

Myelosuppressive effects in vivo of purified recombinant murine macrophage inflammatory protein-1 alpha.

1992 • 80 citations

The Broad Spectrum of Cytokine Gene Expression by Myoid Cells from the Human Marrow Microenvironment

1997 • 77 citations

Modulation of CXCR4 expression and SDF-1α functional activity during differentiation of human monocytes and macrophages

1999 • 63 citations

Activation of HIV-1 Coreceptor (CXCR4) Mediates Myelosuppression

1997 • 57 citations

SDF-1 Responsiveness Does Not Correlate With CXCR4 Expression Levels of Developing Human Bone Marrow B Cells

1999 • 51 citations

Role of abnormal integrin-cytoskeletal interactions in impaired β1 integrin function in chronic myelogenous leukemia hematopoietic progenitors

1999 • 50 citations

Expression of monocyte chemotactic protein-3 in human monocytes and endothelial cells.

1997 • 45 citations

The Chemokine FactsBook

1997 • 35 citations

Macrophage inflammatory protein-1 alpha receptors are present on cells enriched for CD34 expression from patients with chronic myeloid leukemia

1995 • 35 citations

Heterogeneity in expression of the bcr-abl fusion transcript in CML blast crisis.

1987 • 28 citations

Differential Response of CD34⁺Cells Isolated from Cord Blood and Bone Marrow to MIP‐1α and the Expression of MIP‐1α Receptors on These Immature Cells

1998 • 24 citations

TCR-mediated activation of allergen-specific CD45RO+ memory T lymphocytes results in down-regulation of cell-surface CXCR4 expression and a strongly reduced capacity to migrate in response to stromal cell-derived factor-1

1999 • 24 citations

New strategies for the treatment of chronic myeloid leukemia [editorial; comment]

1994 • 23 citations

Characterisation of the differential response of normal and CML haemopoietic progenitor cells to macrophage inflammatory protein-1α

1999 • 17 citations

Molecular analysis of hematopoietic colonies derived from chronic myeloid leukemia patients: interphase fluorescence in situ hybridization compared with RT-PCR

1997 • 16 citations

Distinct Biological Effects of Macrophage Inflammatory Protein‐1α and Stroma‐Derived Factor‐1α on CD34 ⁺ Hemopoietic Cells

1999 • 15 citations