The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1996 • 2,374 citations

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

1989 • 1,993 citations

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1996 • 1,973 citations

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1996 • 1,678 citations

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

1996 • 1,482 citations

The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

1997 • 1,414 citations

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

1997 • 1,124 citations

Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells

1991 • 869 citations

Molecular cloning and structure of a pre-B-cell growth-stimulating factor.

1994 • 818 citations

Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins

1993 • 722 citations

Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro

1989 • 699 citations

Expression of Thy-1 on human hematopoietic progenitor cells.

1993 • 477 citations

Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin

1996 • 322 citations

Sustained, retransplantable, multilineage engraftment of highly purified adult human bone marrow stem cells in vivo

1996 • 221 citations

Molecular Cloning of the cDNA and Chromosomal Localization of the Gene for a Putative Seven-Transmembrane Segment (7-TMS) Receptor Isolated from Human Spleen

1993 • 192 citations

Functional expression of the CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes.

1997 • 182 citations

CD34+ bone marrow cells are infected with HIV in a subset of seropositive individuals.

1992 • 173 citations

Results of MDR-1 vector modification trial indicate that granulocyte/macrophage colony-forming unit cells do not contribute to posttransplant hematopoietic recovery following intensive systemic therapy

1996 • 160 citations

Selectivity and antagonism of chemokine receptors

1996 • 159 citations

Absent or rare human immunodeficiency virus infection of bone marrow stem/progenitor cells in vivo

1991 • 146 citations

Expression of the Human Immunodeficiency Virus Type-1 Coreceptors CXCR-4 (fusin, LESTR) and CKR-5 in CD34+ Hematopoietic Progenitor Cells

1997 • 135 citations

Monocyte-selective transendothelial migration: dissection of the binding and transmigration phases by an in vitro assay.

1992 • 133 citations

Transendothelial Migration of CD34+ and Mature Hematopoietic Cells: An In Vitro Study Using a Human Bone Marrow Endothelial Cell Line

1997 • 133 citations

Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1- cells are more primitive than CD34+ LFA-1+ cells

1992 • 129 citations

Expression of CD4 by human hematopoietic progenitors [see comments]

1994 • 101 citations

CD34+ progenitor cells from asymptomatic patients are not a major reservoir for human immunodeficiency virus-1

1995 • 98 citations

Characterization of functionally distinct subpopulations of CD34+ cord blood cells in serum-free long-term cultures supplemented with hematopoietic cytokines

1993 • 96 citations

A subset of human CD34+ hematopoietic progenitors express low levels of CD4, the high-affinity receptor for human immunodeficiency virus-type 1

1994 • 95 citations

In vitro human immunodeficiency virus-1 infection of purified hematopoietic progenitors in single-cell culture

1995 • 95 citations

Loss of primitive hematopoietic progenitors in patients with human immunodeficiency virus infection

1996 • 90 citations

Characterization of functionally distinct subpopulations of CD34+ cord blood cells in serum-free long-term cultures supplemented with hematopoietic cytokines

1993 • 77 citations

Cloning of the mouse fusin gene, homologue to a human HIV-1 co-factor.

1996 • 71 citations

BMEC-1: A Human Bone Marrow Microvascular Endothelial Cell Line with Primary Cell Characteristics

1996 • 65 citations

Alternate splicing of mouse fusin/CXC chemokine receptor-4: stromal cell-derived factor-1alpha is a ligand for both CXC chemokine receptor-4 isoforms.

1997 • 45 citations

Exposure of human CD34+ cells to human immunodeficiency virus type 1 does not influence their expansion and proliferation of hematopoietic progenitors in vitro

1996 • 28 citations