Phosphatidylcholine breakdown in rat liver plasma membranes. Roles of guanine nucleotides and P2-purinergic agonists.

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Computer calculation of equilibrium concentrations in mixtures of metal ions and complexing species

1967 • 642 citations

Improved separation of phospholipids in thin layer chromatography

1980 • 485 citations

5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide breakdown.

1985 • 429 citations

Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.

1986 • 415 citations

Regulation of phosphatidylcholine biosynthesis

1984 • 401 citations

Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.

1986 • 378 citations

Chemoattractant receptor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in human polymorphonuclear leukocyte membranes. Requirement for a guanine nucleotide regulatory protein.

1985 • 358 citations

Guanine nucleotide-binding regulatory proteins and dual control of adenylate cyclase.

1984 • 342 citations

Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium.

1985 • 315 citations

Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II.

1985 • 304 citations

Vasopressin-, angiotensin II-, and alpha 1-adrenergic-induced inhibition of Ca2+ transport by rat liver plasma membrane vesicles.

1984 • 279 citations

Characterization of responses of isolated rat hepatocytes to ATP and ADP.

1985 • 269 citations

A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.

1986 • 267 citations

Quantitation and early kinetics of inositol lipid changes induced by vasopressin in isolated and cultured hepatocytes.

1983 • 232 citations

Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate.

1985 • 218 citations

Stimulation of inositol trisphosphate formation in hepatocytes by vasopressin, adrenaline and angiotensin II and its relationship to changes in cytosolic free Ca2+

1985 • 212 citations

Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.

1986 • 198 citations

Thyrotropin-releasing hormone and GTP activate inositol trisphosphate formation in membranes isolated from rat pituitary cells.

1986 • 169 citations

Choline metabolism and phosphatidylcholine biosynthesis in cultured rat hepatocytes

1981 • 124 citations

Role of calcium and phosphoinositides in the actions of certain hormones and neurotransmitters.

1985 • 122 citations

Direct stimulation by thyrotropin-releasing hormone (TRH) of polyphosphoinositide hydrolysis in GH3 cell membranes by a guanine nucleotide-modulated mechanism

1985 • 99 citations

Effect of islet-activating pertussis toxin on the binding characteristics of Ca2+-mobilizing hormones and on agonist activation of phosphorylase in hepatocytes.

1986 • 86 citations

Regulation of a liver plasma membrane phosphoinositide phosphodiesterase by guanine nucleotides and calcium

1985 • 83 citations

Mechanism of hepatic glycogen synthase inactivation induced by Ca2+-mobilizing hormones. Studies using phospholipase C and phorbol myristate acetate

1986 • 68 citations

Activation of membrane phospholipase C by vasopressin

1986 • 65 citations

A transient increase in diacylglycerols is associated with the action of vasopressin on hepatocytes

1984 • 53 citations

Novel, selective purinoceptor antagonists: investigation of ATP as a neurotransmitter

1985 • 27 citations