Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

1977 • 2,134 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

1987 • 640 citations

Induction of Differentiation in Human Promyelocytic Leukemia Cells by Tumor Promoters

1979 • 594 citations

Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.

1986 • 424 citations

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1984 • 418 citations

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

1984 • 389 citations

Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.

1986 • 378 citations

Signal transduction by guanine nucleotide binding proteins

1987 • 362 citations

Molecular mechanisms of transmembrane signalling

1985 • 352 citations

Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils

1986 • 339 citations

Inositol 1,3,4,5-tetrakisphosphate and not phosphatidylinositol 3,4-bisphosphate is the probable precursor of inositol 1,3,4-trisphosphate in agonist-stimulated parotid gland

1986 • 283 citations

Guanine nucleotides induce Ca2+-independent insulin secretion from permeabilized RINm5F cells.

1987 • 244 citations

Guanine nucleotides decrease the free [Ca²⁺] required for secretion of serotonin from permeabilized blood platelets

1984 • 236 citations

Regulation of the phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by a pertussis toxin-sensitive guanine nucleotide-binding protein. Evaluation of its contribution to platelet activation and comparisons with the adenylate cyclase inhibitory protein, Gi.

1986 • 235 citations

Cyclic Nucleotide-induced Maturation of Human Promyelocytic Leukemia Cells

1982 • 213 citations

Thyrotropin-releasing hormone activates a Ca2+-dependent polyphosphoinositide phosphodiesterase in permeable GH3 cells. GTP gamma S potentiation by a cholera and pertussis toxin-insensitive mechanism.

1986 • 197 citations

Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells.

1987 • 188 citations

Light activation of phospholipase A2 in rod outer segments of bovine retina and its modulation by GTP-binding proteins.

1987 • 186 citations

Guanine nucleotide effects on catecholamine secretion from digitonin-permeabilized adrenal chromaffin cells.

1986 • 131 citations

Rat mast cells permeabilised with streptolysin O secrete histamine in response to Ca2+ at concentrations buffered in the micromolar range

1987 • 126 citations

Fluoroaluminates mimic guanosine 5′-[γ-thio]triphosphate in activating the polyphosphoinositide phosphodiesterase of hepatocyte membranes. Role for the guanine nucleotide regulatory protein Gp in signal transduction

1987 • 110 citations

Development of the superoxide-generating system during differentiation of the HL-60 human promyelocytic leukemia cell line.

1984 • 87 citations

5-Methyltryptamine stimulates phospholipase C-mediated breakdown of exogenous phosphoinositides by blowfly salivary gland membranes.

1985 • 81 citations

Use of cytochalasin B to distinguish between early and late events in neutrophil activation

1980 • 80 citations

Subcellular localisation of inositol lipid kinases in rat liver

1985 • 74 citations

Rat mast cells permeabilized with Sendai virus secrete histamine in response to Ca2+ buffered in the micromolar range

1983 • 68 citations

The dependence on Ca2+ of the guanine-nucleotide-activated polyphosphoinositide phosphodiesterase in neutrophil plasma membranes

1986 • 66 citations

Differential control of azurophilic and specific granule exocytosis in Sendai‐virus‐permeabilized rabbit neutrophils.

1987 • 58 citations

Terminal differentiation of the human promyelocytic leukemia cell line, HL-60, in the absence of cell proliferation.

1982 • 55 citations

Effect of various excitatory agonists on the secretion of 5‐hydroxytryptamine from permeabilised human platelets induced by Ca²⁺ in the presence or absence of GTP

1985 • 47 citations

Development of Chemotaxis and Formyl Peptide Binding in Human Promyelocytic Leukemia Cell Line (HL60)

1982 • 14 citations