Activation of human neutrophil phospholipase D by three separable mechanisms

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1986 • 999 citations

Transphosphatidylation by Phospholipase D

1967 • 563 citations

Growth factor-like action of phosphatidic acid

1986 • 531 citations

Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism.

1987 • 472 citations

Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro.

1985 • 380 citations

Cellular ras activity and phospholipid metabolism

1988 • 331 citations

Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes.

1988 • 307 citations

Choline-linked Phosphoglycerides

1989 • 234 citations

Phosphatidic acid may stimulate membrane receptors mediating adenylate cyclase inhibition and phospholipid breakdown in 3T3 fibroblasts.

1987 • 219 citations

Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and -independent mechanisms.

1988 • 197 citations

A diacylglycerol analogue reduces neuronal calcium currents independently of protein kinase C activation

1989 • 190 citations

1-ether-linked phosphoglycerides. Major endogenous sources of arachidonate in the human neutrophil.

1988 • 180 citations

P2-Purinergic Agonists Stimulate Phosphodiesteratic Cleavage of Phosphatidylcholine in Endothelial Cells

1989 • 180 citations

Two transduction sequences are necessary for neutrophil activation by receptor agonists.

1988 • 172 citations

Receptor regulation of choline phospholipid hydrolysis

1989 • 167 citations

Phosphatidylethanol Biosynthesis in Ethanol-exposed NG108-15 Neuroblastoma X Glioma Hybrid Cells

1989 • 151 citations

Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues

1987 • 142 citations

Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils.

1987 • 140 citations

Activation of NADPH-dependent superoxide production in plasma membrane extracts of pig neutrophils by phosphatidic acid.

1988 • 138 citations

12-O-tetradecanoylphorbol-13-acetate activates phosphatidylethanol and phosphatidylglycerol synthesis by phospholipase D in cell lysates

1988 • 78 citations

Evidence for a protein kinase C‐directed mechanism in the phorbol diester‐induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine

1989 • 74 citations

Phospholipids containing polyunsaturated fatty acyl groups are mitogenic for normal mouse mammary epithelial cells in serum-free primary cell culture.

1989 • 62 citations

Stimulus-dependent mobilization of protein kinase C

1986 • 60 citations

Selective priming of rate and duration of the respiratory burst of neutrophils by 1,2-diacyl and 1-O-alkyl-2-acyl diglycerides. Possible relation to effects on protein kinase C.

1988 • 59 citations

Stimulation of quiescent 3T3 cells by phosphatidic acid-containing liposomes

1987 • 58 citations

12-O-Tetradecanoylphorbol-13-acetate activates the synthesis of phosphatidylethanol in animal cells exposed to ethanol

1987 • 50 citations

Quantitation of lyso-platelet activating factor molecular species from human neutrophils by mass spectrometry.

1986 • 38 citations