Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

Identification of a nuclear protein matrix

1974 • 1,016 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1989 • 597 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Localization of topoisomerase II in mitotic chromosomes.

1985 • 501 citations

In situ localization of DNA topoisomerase II, a major polypeptide component of the Drosophila nuclear matrix fraction.

1985 • 472 citations

Biological Significance of Unwinding Capability of Nuclear Matrix-Associating DNAs

1992 • 407 citations

Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions.

1989 • 317 citations

Transcription occurs at a nucleoskeleton.

1985 • 303 citations

The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain.

1988 • 280 citations

Dysfunction of chromosomal loop attachment sites: illegitimate recombination linked to matrix association regions and topoisomerase II.

1989 • 206 citations

The nucleoskeleton and the topology of replication

1991 • 205 citations

A matrix/scaffold attachment region binding protein: Identification, purification, and mode of binding

1991 • 205 citations

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML

1989 • 184 citations

Scaffold-attached regions from the human interferon .beta. domain can be used to enhance the stable expression of genes under the control of various promoters

1991 • 177 citations

Eukaryotic topoisomerase II preferentially cleaves alternating purine-pyrimidine repeats

1990 • 170 citations

Chromatin domain surrounding the human interferon-.beta. gene as defined by scaffold-attached regions

1988 • 169 citations

Highly preferential nucleation of histone H1 assembly on scaffold-associated regions

1989 • 165 citations

A comprehensive study on the isolation and characterization of the hela S3 nuclear matrix

1991 • 152 citations

RAP1 is required for BAS1/BAS2- and GCN4-dependent transcription of the yeast HIS4 gene.

1991 • 147 citations

The nucleoskeleton and the topology of transcription

1989 • 110 citations

Anchorage of the Chinese hamster dihydrofolate reductase gene to the nuclear scaffold occurs in an intragenic region

1987 • 99 citations

DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast.

1991 • 98 citations

Tissue Specificity of the Hormonal Response in Sex Accessory Tissues Is Associated with Nuclear Matrix Protein Patterns

1990 • 97 citations

A domain model for eukaryotic DNA organization: A molecular basis for cell differentiation and chromosome evolution

1988 • 97 citations

DNA polymerase α is tightly bound to the nuclear matrix of actively replicating liver

1980 • 91 citations

DNA binding properties of the nuclear matrix and individual nuclear matrix proteins. Evidence for salt-resistant DNA binding sites

1991 • 80 citations

Molecular cloning of matrin F/G: A DNA binding protein of the nuclear matrix that contains putative zinc finger motifs.

1991 • 74 citations

Asymmetric DNA Bending Induced by the Yeast Multifunctional Factor TUF

1989 • 74 citations

The nucleus: A black box being opened

1991 • 73 citations

Studies of an 800-kilobase DNA stretch of the Drosophila X chromosome: comapping of a subclass of scaffold-attached regions with sequences able to replicate autonomously in Saccharomyces cerevisiae.

1990 • 60 citations

Active RNA polymerase I is fixed within the nucleus of HeLa cells.

1990 • 58 citations

Structure of the human type I DNA topoisomerase gene

1991 • 57 citations

DNA binding properties of a 110kDa nucleolar protein

1986 • 51 citations

RAP1 Is Required for BAS1/BAS2- and GCN4-Dependent Transcription of the Yeast HIS4 Gene

1991 • 48 citations

Chromosomal loop/nuclear matrix organization of transcriptionally active and inactive RNA polymerases in HeLa nuclei

1988 • 34 citations

A newly detected class of mammalian single strand-specific DNA-binding proteins. Effects on DNA polymerase alpha-catalyzed DNA synthesis.

1985 • 33 citations

Simultaneous Purification of DNA Topoisomerase I and II from Eukaryotic Cells

1989 • 33 citations

Renaturation and DNA looping promoted by the SV40 large tumour antigen.

1990 • 18 citations

Replication of SV40 chromatin in extracts from eggs of Xenopus laevis

1981 • 17 citations

Origins of replication: timing and chromosomal position

1991 • 13 citations