Relationship Between Cytosolic Free Calcium Ion Concentration and the Control of Pyruvate Dehydrogenase in Isolated Cardiac Myocytes and Synaptosomes

CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION

1966 • 3,631 citations

The Respiratory Chain and Oxidative Phosphorylation

1956 • 2,073 citations

Specific inhibition of mitochondrial Ca++ transport by ruthenium red

1971 • 616 citations

Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

1972 • 519 citations

The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex

1979 • 431 citations

Membrane potentials in pinched‐off presynaptic nerve ternimals monitored with a fluorescent probe: evidence that synaptosomes have potassium diffusion potentials.

1975 • 389 citations

Contractile proteins of the heart.

1970 • 365 citations

Calcium ions and the regulation of NAD+-linked isocitrate dehydrogenase from the mitochondria of rat heart and other tissues

1978 • 359 citations

Compartmentation and Communication in Living Systems. Ligand Conduction: a General Catalytic Principle in Chemical, Osmotic and Chemiosmotic Reaction Systems

1979 • 349 citations

Role of calcium ions in the regulation of intramitochondrial metabolism. Effects of Na+, Mg2+ and ruthenium red on the Ca2+-stimulated oxidation of oxoglutarate and on pyruvate dehydrogenase activity in intact rat heart mitochondria

1980 • 292 citations

Calcium and cAMP as synarchic messengers

1982 • 284 citations

α-Keto acid dehydrogenase complexes

1972 • 278 citations

Effects of veratrum alkaloids on membrane potential and conductance of squid and crayfish giant axons.

1973 • 252 citations

α-Keto acid dehydrogenase complexes

1972 • 244 citations

Effect of glucagon on metabolite compartmentation in isolated rat liver cells during gluconeogenesis from lactate

1977 • 234 citations

Ryanodine modification of cardiac muscle responses to potassium-free solutions. Evidence for inhibition of sarcoplasmic reticulum calcium release.

1983 • 191 citations

Function of calcium ions in pyruvate dehydrogenase phosphatase activity

1972 • 157 citations

Control of Mitochondrial Substrate Oxidation

1980 • 151 citations

Studies on the effects of coenzyme A-SH: acetyl coenzyme A, nicotinamide adenine dinucleotide: reduced nicotinamide adenine dinucleotide, and adenosine diphosphate: adenosine triphosphate ratios on the interconversion of active and inactive pyruvate dehydrogenase in isolated rat heart mitochondria.

1976 • 117 citations

Biochemical Studies of Synapses in Vitro

1969 • 110 citations

Frequency, amplitude, and propagation velocity of spontaneous Ca++-dependent contractile waves in intact adult rat cardiac muscle and isolated myocytes.

1985 • 103 citations

The stimulatory effect of glucagon and dibutyryl cyclic AMP on ureogenesis and gluconeogenesis in relation to the mitochondrial ATP contnet

1977 • 94 citations

Role of Ca2+ in pyruvate dehydrogenase interconversion in brain mitochondria and synaptosomes

1985 • 89 citations

Relation between cytosolic free Ca2+ concentration and the control of pyruvate dehydrogenase in isolated cardiac myocytes

1987 • 83 citations

Cytoplasmic free calcium measured by quin2 fluorescence in isolated ventricular myocytes at rest and during potassium-depolarization

1984 • 72 citations

Biochemical studies of synapses in vitro. II. Potassium transport

1969 • 72 citations

Effect of micromolar concentrations of free Ca2+ ions on pyruvate dehydrogenase interconversion in intact rat heart mitochondria

1981 • 69 citations

Effect of micromolar concentrations of free calcium ions on the reduction of heart mitochondrial NAD(P) by 2-oxoglutarate

1981 • 68 citations

4 β-Phorbol 12-myristate 13-acetate attenuates the glucagon-induced increase in cytoplasmic free Ca2+ concentration in isolated rat hepatocytes

1986 • 56 citations

Na+-Ca2+ exchange contributes to increase of cytosolic Ca2+ concentration during depolarization in heart muscle

1986 • 49 citations

The glucagon-induced activation of pyruvate dehydrogenase in hepatocytes is diminished by 4β-phorbol 12-myristate 13-acetate. A role for cytoplasmic Ca2+ in dehydrogenase regulation

1987 • 32 citations

The nature of controlled respiration and its relationship to protonmotive force and proton conductance in blowfly flight-muscle mitochondria

1977 • 28 citations

The effect of adenine nucleotides upon the 2‐oxoglutarate dehydrogenase of blowfly flight muscle

1972 • 21 citations