The T Cell Activation Molecule CD27 Is a Member of the Nerve Growth Factor Receptor Gene Family

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

RECEPTORS FOR EPIDERMAL GROWTH FACTOR AND OTHER POLYPEPTIDE MITOGENS

1987 • 1,274 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Mechanism of antigen-driven selection in germinal centres

1989 • 1,097 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Molecular cloning and expression of a receptor for human tumor necrosis factor

1990 • 973 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

1990 • 918 citations

Zinc fingers: Gilt by association

1988 • 799 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

Leukocyte Typing II

1986 • 688 citations

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

1990 • 647 citations

The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 • 645 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

1989 • 527 citations

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction.

1990 • 526 citations

Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts

1987 • 453 citations

Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50.

1986 • 439 citations

A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact

1990 • 409 citations

cDNA sequences of two inducible T-cell genes.

1989 • 392 citations

Nerve growth factor induces growth and differentiation of human B lymphocytes.

1989 • 386 citations

Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor.

1990 • 375 citations

Two Different Cell Types have Different Major Receptors for Human Tumor Necrosis Factor (TNFα)

1989 • 368 citations

Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor alpha.

1990 • 290 citations

Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes.

1985 • 267 citations

Tissue distribution and biochemical and functional properties of Tp55 (CD27), a novel T cell differentiation antigen.

1987 • 231 citations

Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes.

1989 • 230 citations

Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C.

1989 • 226 citations

A p50 surface antigen restricted to human urinary bladder carcinomas and B lymphocytes

1985 • 169 citations

Multiple kinases and signal transduction. Phosphorylation of the T cell antigen receptor complex.

1987 • 168 citations

Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression.

1986 • 166 citations

Antibodies to common leukocyte antigen p220 influence human T cell proliferation by modifying IL 2 receptor expression.

1985 • 164 citations

Characterization of the human melanoma nerve growth factor receptor.

1985 • 162 citations

Identification of a truncated form of the nerve growth factor receptor.

1988 • 145 citations

Augmentation of normal and malignant B cell proliferation by monoclonal antibody to the B cell-specific antigen BP50 (CDW40).

1987 • 141 citations

Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor.

1990 • 139 citations

Structural features of the cytoplasmic region of CD4 required for internalization.

1990 • 111 citations

The human B lymphocyte and carcinoma antigen, CDw40, is a phosphoprotein involved in growth signal transduction.

1989 • 94 citations

Transcriptional and post-transcriptional regulation of TcR, CD4 and CD8 gene expression during activation of normal human T lymphocytes.

1990 • 88 citations

Tumorigenic poxviruses: Genomic organization and dna sequence of the telomeric region of the shope fibroma virus genome

1987 • 75 citations

Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40.

1989 • 64 citations

T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation

1986 • 60 citations

S152 (CD27). A modulating disulfide-linked T cell activation antigen.

1988 • 50 citations

Mechanisms of immune memory. T cell activation and CD3 phosphorylation correlates with Ta1 (CDw26) expression.

1989 • 49 citations

The influence of cyclosporin A on the alternative pathways of human T cell activation in vitro

1989 • 43 citations

CD27 induction on thymocytes.

1990 • 35 citations

Alternative molecular form of human T cell‐specific antigen CD27 expressed upon T cell activation

1989 • 34 citations

Anti‐CD27 monoclonal antibodies identify two functionally distinct subpopulations within the CD4⁺ T cell subset

1988 • 28 citations

Effect of tumor promoter 12‐O‐tetradecanoyl‐phorbol l3‐acetate on CD 7 expression by T lineage cells

1988 • 12 citations

A Novel Disulfide-Linked Cell Surface Molecule Present on Resting and Activated Human T Lymphocytes

1986 • 6 citations