Transcriptional and post-transcriptional regulation of TcR, CD4 and CD8 gene expression during activation of normal human T lymphocytes.

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1984 • 858 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1989 • 671 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

T cell antigen receptors and the immunoglobulin supergene family

1985 • 453 citations

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

1989 • 447 citations

A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes

1987 • 446 citations

Northern blot normalization with a 28S rRNA olinucleotide probe

1989 • 364 citations

The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes

1985 • 325 citations

Cross-linking of human T cell receptor proteins: association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit

1985 • 303 citations

Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor

1987 • 265 citations

Regulation of T-cell receptor γ-chain RNA expression in murine Thy-1+ dendritic epidermal cells

1987 • 213 citations

Clonal Heterogeneity in the Functional Requirement for Lyt‐2/3 Molecules on Cytolytic T Lymphocytes (CTL): Possible Implications for the Affinity of CTL Antigen Receptors

1982 • 204 citations

A γ-chain complex forms a functional receptor on cloned human lymphocytes with natural killer-like activity

1987 • 199 citations

Regulation of c-myc mRNA Stability In Vitro by a Labile Destabilizer with an Essential Nucleic Acid Component

1989 • 172 citations

Modulation of CD4 by antigenic activation.

1987 • 138 citations

Transient modulation and internalization of T4 antigen induced by phorbol esters.

1986 • 137 citations

Internalization and cycling of the T cell antigen receptor. Role of protein kinase C.

1987 • 133 citations

Kinases and phosphatases in T-cell activation

1989 • 118 citations

T cell receptor triggering induces responsiveness to interleukin 1 and interleukin 2 but does not lead to T cell proliferation.

1986 • 113 citations

Association of phosphorylation of the T3 antigen with immune activation of T lymphocytes

1987 • 91 citations

Phosphorylation of CD4 and CD8 molecules following T cell triggering.

1987 • 87 citations

Posttranscriptional Stabilization of c-fms mRNA by a Labile Protein during Human Monocytic Differentiation

1989 • 85 citations

Evidence for an association between CD8 molecules and the T cell receptor complex on cytotoxic T cells.

1987 • 83 citations

Transmembrane signals in the activation of T lymphocytes by mitogenic antigens

1988 • 83 citations

Molecular cloning and expression of T11 cDNAs reveal a receptor-like structure on human T lymphocytes.

1987 • 78 citations

The T4 surface antigen is involved in the induction of helper function.

1984 • 77 citations

A conserved sequence in the T-cell receptor beta-chain promoter region.

1988 • 74 citations

Stimulation and proliferation of CD4⁺ peripheral blood T lymphocytes induced by an anti‐CD4 monoclonal antibody

1988 • 68 citations

Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor.

1987 • 50 citations

Cross-linking of CD4 and CD8 with the T-cell receptor complex: quaternary complex formation and T-cell repertoire selection

1988 • 50 citations

Distinct signals are required for proliferation and lymphokine gene expression in murine T cell clones.

1986 • 41 citations

Transcription of T cell antigen receptor genes is induced by protein kinase C activation.

1988 • 35 citations

Multiple nuclear proteins bind upstream sequences in the promotor region of a T-cell receptor beta-chain variable-region gene: evidence for tissue specificity.

1987 • 31 citations

Regulation of expression of T cell γ chain, L3T4 and Ly-2 messages in Abelson/moloney virus-transformed T cell lines

1988 • 30 citations

Translation of mRNA from Phytohemagglutinin-stimulated Human Lymphocytes: Characterization of Interferon mRNAs

1982 • 29 citations

Kinetics of messenger accumulation coding for IFN γ, related to modifications in the poly(A) RNA population of activated human lymphocytes

1984 • 28 citations

Lymphokine mRNA and T cell multireceptor mRNA of the Ig super gene family are reciprocally modulated during human T cell activation

1988 • 24 citations

Changes in gene expression induced by a phorbol diester: expression of IL 2 receptor, T3, and T cell antigen receptor.

1987 • 24 citations

Antagonistic effects of calcium ionophores and phorbol esters on T cell receptor mRNA levels in human thymocytes.

1988 • 16 citations