Dependency on intercellular adhesion molecule recognition and local interleukin-2 provision in generation of an in vivo CD8+ T-cell immune response to murine myeloid leukemia

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Graft-versus-leukemia reactions after bone marrow transplantation

1990 • 2,781 citations

The Concept of Immunological Surveillance

2015 • 1,586 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens

1994 • 1,185 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Biology and clinical relevance of human natural killer cells

1990 • 930 citations

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1990 • 926 citations

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells.

1987 • 523 citations

Alloreactive murine CD8+ T cell clones secrete the Th1 pattern of cytokines.

1990 • 240 citations

Effects of a cloned cell line with NK activity on bone marrow transplants, tumour development and metastasis in vivo

1982 • 228 citations

The Human Interleukin-2 Receptor

1986 • 209 citations

A Survey of Transplantable and Transmissible Animal Tumors

1953 • 194 citations

Characterization of the function of intercellular adhesion molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune responses.

1994 • 172 citations

Interleukin-2 may induce prolonged remissions in advanced acute myelogenous leukemia

1994 • 114 citations

Eradication of disseminated murine leukemia by treatment with high-dose interleukin 2.

1986 • 105 citations

Murine epidermal Langerhans cells and splenic dendritic cells present tumor‐associated antigens to primed T cells

1994 • 104 citations

Tumor escape mechanisms from immunosurveillance: induction of unresponsiveness in a specific MHC-restricted CD4⁺; human T cell clone by the autologous MHC class II⁺ melanoma

1993 • 90 citations

Inhibition of clonogenic growth of fresh leukemia cells by unstimulated and IL-2 stimulated NK cells of normal donors

1987 • 82 citations

T cells from tumor-immune mice nonspecifically expanded in vitro with anti-CD3 plus IL-2 retain specific function in vitro and can eradicate disseminated leukemia in vivo.

1991 • 66 citations

Increased local antitumor effects of interleukin 2 liposomes in mice with MCA-106 sarcoma pulmonary metastases.

1990 • 63 citations

Bone marrow transplantation with interleukin-2-activated bone marrow followed by interleukin-2 therapy for acute myeloid leukemia in mice

1990 • 61 citations

Depot Characteristics and Biodistribution of Interleukin-2 Liposomes, Importance of Route of Administration

1992 • 60 citations

Identification and quantification of a naturally presented peptide as recognized by cytotoxic T lymphocytes specific for an immunogenic tumor variant

1992 • 59 citations

Friend virus-specific cytotoxic T lymphocytes recognize both gag and env gene-encoded specificities.

1986 • 53 citations

Pathology of Leukemia

1969 • 52 citations

Immunotherapy of leukemia.

1992 • 31 citations

Interleukin-2 Gene Transfer into Murine Neuroblastoma Decreases Tumorigenicity and Enhances Systemic Immunity Causing Regression of Preestablished Retroperitoneal Tumors

1994 • 30 citations

Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents.

1966 • 26 citations

Possible mechanism of selective killing of myeloid leukemic blast cells by lymphokine-activated killer cells

1991 • 26 citations

Interleukin-2 therapy after autologous bone marrow transplantation for hematologic malignancies.

1993 • 25 citations

Preclinical Studies of T-Cell-Mediated Immune Responses Against Autologous Tumor Cells in Patients with Acute Leukemia

1993 • 2 citations

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