T cells from tumor-immune mice nonspecifically expanded in vitro with anti-CD3 plus IL-2 retain specific function in vitro and can eradicate disseminated leukemia in vivo.

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Adoptive T Cell Therapy of Tumors: Mechanisms Operative in the Recognition and Elimination of Tumor Cells

1991 • 619 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials

1987 • 361 citations

The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells

1990 • 353 citations

The Murine Antitumor Immune Response and Its Therapeutic Manipulation

1984 • 164 citations

Adoptive immunotherapy of newly induced murine sarcomas.

1985 • 137 citations

Specificity of adoptive chemoimmunotherapy of established syngeneic tumors.

1980 • 121 citations

Effective activation of resting mouse T lymphocytes by cross‐linking submitogenic concentrations of the T cell antigen receptor with either Lyt‐2 or L3T4

1987 • 120 citations

Antigen-driven long term-cultured T cells proliferate in vivo, distribute widely, mediate specific tumor therapy, and persist long-term as functional memory T cells.

1986 • 97 citations

Requirement for recognition of class II molecules and processed tumor antigen for optimal generation of syngeneic tumor-specific class I-restricted CTL.

1986 • 97 citations

Activation of human tumor-infiltrating lymphocytes by monoclonal antibodies directed to the CD3 complex.

1990 • 66 citations

Adoptive immunotherapy of a newly induced sarcoma: immunologic characteristics of effector cells.

1985 • 57 citations

Efficient Propagation and Cloning of Human T Cells in the Absence of Antigen by Means of OKT3, Interleukin 2, and Antigen‐Presenting Cells

1988 • 49 citations

Distinct proliferative T cell clonotypes are generated in response to a murine retrovirus-induced syngeneic T cell leukemia: viral gp70 antigen-specific MT4+ clones and Lyt-2+ cytolytic clones which recognize a tumor-specific cell surface antigen.

1985 • 44 citations

Solid-phase anti-CD3 antibody activation of murine tumor-infiltrating lymphocytes.

1990 • 38 citations