Distinct arginase isoforms expressed in primary and transformed macrophages: regulation by oxygen tension

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

1994 • 2,659 citations

Purification and Characterization of Hypoxia-inducible Factor 1

1995 • 2,010 citations

Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

1996 • 1,088 citations

Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1

1996 • 1,081 citations

Comparative properties of arginases

1996 • 604 citations

Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.

1994 • 584 citations

Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. Role of IFN-gamma in the induction of the nitric oxide-synthesizing pathway.

1991 • 384 citations

The regulated expression of erythropoietin by two human hepatoma cell lines.

1987 • 374 citations

Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms.

1994 • 372 citations

Temporal expression of different pathways of 1-arginine metabolism in healing wounds.

1990 • 351 citations

Activated macrophages kill tumour cells by releasing arginase

1978 • 307 citations

Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage‐like cell line

1996 • 238 citations

Coinduction of Nitric-oxide Synthase and Arginase I in Cultured Rat Peritoneal Macrophages and Rat Tissues in Vivo by Lipopolysaccharide

1997 • 215 citations

Co-induction of Arginase and Nitric Oxide Synthase in Murine Macrophages Activated by Lipopolysaccharide

1995 • 213 citations

Arginine metabolism in wounds

1988 • 196 citations

Suppression of in vitro cytotoxic response by macrophages due to induced arginase.

1977 • 189 citations

Natural resistance and nitric oxide

1995 • 181 citations

Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774

1992 • 148 citations

Suppression of lymphocyte proliferation through the nitric oxide synthesizing pathway

1991 • 135 citations

Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level

1993 • 123 citations

Macrophage activation by culture in an anoxic environment.

1995 • 120 citations

Microenvironmental arginine depletion by macrophages in vivo

1979 • 99 citations

Complete nucleotide sequence of cDNA and deduced amino acid sequence of rat liver arginase.

1987 • 95 citations

Diphenylene Iodonium Inhibits the Induction of Erythropoietin and Other Mammalian Genes by Hypoxia

1995 • 91 citations

Activated T cells express a novel gene on chromosome 8 that is closely related to the murine ecotropic retroviral receptor.

1990 • 85 citations

Mutagenesis of Rat Liver Arginase Expressed in Escherichia coli: Role of Conserved Histidines

1994 • 82 citations

Loss of resolution in gel electrophoresis of RNA: a problem associated with the presence of formaldehyde gradients.

1993 • 82 citations

Isolation of human liver arginase cdna and demonstration of nonhomology between the two human arginase genes

1986 • 77 citations

Nitric oxide in inflammation and immunity.

1995 • 64 citations

Normal Fibroblasts Induce the C/EBPβ and ATF-4 bZIP Transcription Factors in Response to Anoxia

1995 • 54 citations

Structural organization of the gene for rat liver-type arginase.

1988 • 52 citations

A mammalian arginine/lysine transporter uses multiple promoters.

1995 • 49 citations

Regulation of CAT: Cationic amino acid transporter gene expression

1996 • 45 citations

Retroposons do jump: a B2 element recently integrated in an 18S rDNA gene

1992 • 40 citations

CCAAT/Enhancer‐Binding Protein β (C/EBPβ) Binds and Activates While Hepatocyte Nuclear Factor‐4 (HNF‐4) does not Bind but Represses the Liver‐Type Arginase Promoter

1996 • 36 citations

Purification, affinity to anti-human arginase immunoglobulin-Sepharose 4B and subunit molecular weights of mammalian arginases

1985 • 31 citations

Über den Stoffwechsel der Tumoren. I. Mitteilung.

1927 • 29 citations

Arginase production by peritoneal macrophages: A new assay

1980 • 26 citations

Mouse Macrophage Arginase

1980 • 19 citations

Differential expression of inducible NO synthase in two murine macrophage cell lines

1996 • 17 citations

Demonstration of a concanavalin A‐induced lymphokine enhancing arginase activity. Effect of presensitization by a skin allograft

1983 • 6 citations