Suppression of lymphocyte proliferation through the nitric oxide synthesizing pathway

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Biosynthesis of nitric oxide from l-arginine

1989 • 1,220 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

Macrophage Oxidation of L-Arginine to Nitric Oxide, Nitrite, and Nitrate

1989 • 681 citations

Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells.

1988 • 592 citations

Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.

1981 • 527 citations

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

1989 • 464 citations

Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible.

1986 • 421 citations

Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages.

1988 • 337 citations

Methemoglobinemia: A Comprehensive Treatise

2019 • 285 citations

Mechanisms by which Activated Macrophages Inhibit Lymphocyte Responses

1978 • 228 citations

Arginine metabolism in wounds

1988 • 196 citations

Regulation of macrophage functions by L-arginine.

1989 • 173 citations

Regulation of macrophage physiology by L-arginine: role of the oxidative L-arginine deiminase pathway.

1989 • 128 citations

Influence of haemoglobin and erythrocytes on the effects of EDRF, a smooth muscle inhibitory factor, and nitric oxide on vascular and non‐vascular smooth muscle

1988 • 81 citations

Inhibition Involves the Iron-Sulfur Prosthetic Group and Is Reversible

1986 • 49 citations

Macrophage-like suppressor cells in rats

1980 • 23 citations

Separation and estimation of arginine-related metabolites in tissues

1980 • 20 citations

Rapid, quantitative microassay for the monokine respiration inhibitory factor

1987 • 17 citations

cGMP and calcium in the initiation of cellular proliferation.

1978 • 13 citations

cGMP and calcium in the initiation of cellular proliferation.

1978 • 10 citations