Temporal changes in metallothionein gene transcription in rat kidney and liver: relationship to content of mercury and metallothionein protein.

Regulation of metallothionein gene expression by oxidative stress and metal ions

2000 • 810 citations

The elusive function of metallothioneins

1998 • 676 citations

Molecular interactions with mercury in the kidney.

2000 • 617 citations

Transcriptional regulation of the mouse metallothionein-I gene by heavy metals.

1981 • 601 citations

Regulation of metallothionein gene expression.

1990 • 177 citations

Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts.

1987 • 151 citations

Differential metal response and regulation of human heavy metal-inducible genes

1999 • 140 citations

Mechanisms for protection against copper toxicity

1998 • 119 citations

THE METABOLISM OF MERCURY IN THE RAT STUDIED BY ISOTOPE TECHNIQUES

1960 • 107 citations

METALLOTHIONEIN TRANSGENIC AND KNOCK-OUT MOUSE MODELS IN THE STUDY OF CADMIUM TOXICITY

1998 • 100 citations

Transgenic expression of interleukin 6 in the central nervous system regulates brain metallothionein-I and -III expression in mice

1997 • 75 citations

Autometallographic localization of inorganic mercury in the kidneys of rats: Effect of unilateral nephrectomy and compensatory renal growth

1991 • 74 citations

Enhanced renal toxicity by inorganic mercury in metallothionein-null mice.

1997 • 70 citations

Cadmium, metallothionein and renal tubular toxicity.

1992 • 65 citations

Evidence for differences in the post-transcriptional regulation of rat metallothionein isoforms

1996 • 56 citations

Accumulation of inorganic mercury along the renal proximal tubule of the rabbit

1990 • 55 citations

Renal metallothionein metabolism after a reduction of renal mass. II. Effect of zinc pretreatment on the renal toxicity and intrarenal accumulation of inorganic mercury

1992 • 49 citations

Strain difference in sensitivity of mice to renal toxicity of inorganic mercury.

1998 • 47 citations

Method for studying the in vivo accumulation of inorganic mercury in segments of the nephron in the kidneys of rats treated with mercuric chloride

1991 • 44 citations

Decreased hepatobiliary secretion of inorganic mercury, its deposition and toxicity in the Eisai hyperbilirubinemic rat with no hepatic canalicular organic anion transporter

1998 • 36 citations

Pulmonary toxicity caused by acute exposure to mercury vapor is enhanced in metallothionein-null mice

1999 • 35 citations

Disposition of Inorganic Mercury Following Biliary Obstruction and Chemically Induced Glutathione Depletion: Dispositional Changes One Hour after the Intravenous Administration of Mercuric Chloride

1999 • 31 citations

Effects of Metals on Gene Expression

1995 • 30 citations

Abundance of hepatic metallothionein mRNA is increased by protein-synthesis inhibitors. Evidence for transcriptional activation and post-transcriptional regulation

1991 • 29 citations

Renal metallothioein metabolism after a reduction of renal mass. I. Effect of unilateral nephrectomy and compensatory renal growth on basal and metal-induced renal metallothionein metabolism

1992 • 28 citations

A mutant mouse (tx) with increased hepatic metallothionein stability and accumulation

1993 • 23 citations

Progressive Losses of Renal Mass and the Renal and Hepatic Disposition of Administered Inorganic Mercury

1995 • 20 citations

Radioimmunoassay of metallothionein in rabbit, rat, mouse, Chinese hamster, and human cells

1991 • 17 citations

Toxic metal-responsive gene transcription

1996 • 16 citations

Mercury distribution and renal metallothionein induction after subchronic oral exposure in rats

1996 • 16 citations

Amplification of Metallothionein-1 Genes in Mouse Liver Cells in Situ: Extra Copies Are Transcriptionally Active

1988 • 7 citations