Disposition of Inorganic Mercury Following Biliary Obstruction and Chemically Induced Glutathione Depletion: Dispositional Changes One Hour after the Intravenous Administration of Mercuric Chloride

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

1979 • 1,680 citations

Glutathione is required for intestinal function.

1990 • 279 citations

Advances in understanding the renal transport and toxicity of mercury

1994 • 130 citations

Renal glutathione and mercury uptake by kidney*1

1985 • 87 citations

Role of γ-glutamyltranspeptidase in renal uptake and toxicity of inorganic mercury in mice

1990 • 81 citations

Dependence of biliary secretion of inorganic mercury on the biliary transport of glutathione

1984 • 81 citations

Organic Anion Transport and Action of γ-Glutamyl Transpeptidase in Kidney Linked Mechanistically to Renal Tubular Uptake of Inorganic Mercury

1995 • 81 citations

Glutathione and gamma-glutamyl cycle enzymes in crypt and villus tip cells of rat jejunal mucosa.

1976 • 65 citations

Participation of mercuric conjugates of cysteine, homocysteine, and N-acetylcysteine in mechanisms involved in the renal tubular uptake of inorganic mercury.

1998 • 62 citations

Intrahepatic transport and utilization of biliary glutathione and its metabolites.

1986 • 54 citations

The effect of depletion of nonprotein sulfhydryls by diethyl maleate plus buthionine sulfoximine on renal uptake of mercury in the rat

1986 • 54 citations

Role of extracellular glutathione and γ‐Glutamyltranspeptidase in the disposition and kidney toxicity of inorganic mercury in rats

1994 • 49 citations

Binding of mercury in renal brus-border and basolateral membrane-vesicles

1997 • 45 citations

Accumulation and handling of inorganic mercury in the kidney after coadministration with glutathione

1995 • 39 citations

INTESTINAL HANDLING OF MERCURY IN THE RAT: IMPLICATIONS OF INTESTINAL SECRETION OF INORGANIC MERCURY FOLLOWING BILIARY LIGATION OR CANNULATION

1998 • 37 citations

Renal disposition of mercury in rats after intravenous injection of inorganic mercury and cysteine

1995 • 35 citations

Depletion of glutathione in the kidney and the renal disposition of administered inorganic mercury.

1997 • 35 citations

Renal clearance of glutathione measured in rats pretreated with inhibitors of glutathione metabolism

1987 • 33 citations

BASOLATERAL UPTAKE OF MERCURIC CONJUGATES OF N-ACETYLCYSTEINE AND CYSTEINE IN THE KIDNEY INVOLVES THE ORGANIC ANION TRANSPORT SYSTEM

1998 • 32 citations

Glutathione homeostasis and glutathione s conjugate toxicity in the kidney

1988 • 27 citations

Diversion or prevention of biliary outflow from the liver diminishes the renal uptake of injected inorganic mercury.

1996 • 8 citations