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Decreased hepatobiliary secretion of inorganic mercury, its deposition and toxicity in the Eisai hyperbilirubinemic rat with no hepatic canalicular organic anion transporter

Data up to Jan 2025

Published1998
Citations36
References29

Total Citations Per Year

Abstract

References (29)

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

1993 • 1,905 citations

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

1994 • 850 citations

cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats

1996 • 641 citations

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1994 • 621 citations

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

1993 • 517 citations

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

1995 • 501 citations

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

1994 • 435 citations

A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein.

1994 • 364 citations

Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR

1997 • 294 citations

Glutathione and related enzymes in multidrug resistance

1996 • 239 citations

GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation.

1994 • 204 citations

Biliary excretion of bile acid conjugates in a hyperbilirubinemic mutant sprague-dawley rat

1991 • 154 citations

DEVELOPMENTAL CHANGES IN THE BILIARY EXCRETION OF METHYLMERCURY AND GLU-TATHIONE

1982 • 138 citations

Induction of the Putative Copper ATPases, CopA and Copb, of Enterococcus hirae by Ag+ and Cu2+, and Ag+ Extrusion by CopB

1994 • 106 citations

Dependence of biliary secretion of inorganic mercury on the biliary transport of glutathione

1984 • 81 citations

A new rat mutant with chronic conjugated hyperbilirubinemia and renal glomerular lesions.

1992 • 76 citations

Effect of metallothionein on hepatic disposition of metals.

1978 • 73 citations

Inorganic mercury secretion into bile as a low molecular weight complex

1984 • 60 citations

Studies on the Accumulation, Metabolism and Excretion of Inorganic Mercury (Hg203) after prolonged Subcutaneous Administration to Rats.

1956 • 52 citations

Biliary excretion of bile acid conjugates in a hyperbilirubinemic mutant Sprague-Dawley rat,

1991 • 44 citations

Copper metabolism in the LEC rat: Involvement of induction of metallothionein and disposition of zinc and iron

1991 • 43 citations

The character of a new mutant rats with hyperbilirubinuria syndrome

1986 • 33 citations

Sulfobromophthalein inhibition of glutathione and methylmercury secretion into bile

1985 • 29 citations

Impaired biliary excretion and whole body elimination of methylmercury in rats with a congenital defect in biliary glutathione excretion

1995 • 27 citations

Biliary Excretion of Copper, Metallothionein, and Glutathione into Long-Evans Cinnamon Rats: A Convincing Animal Model for Wilson Disease

1995 • 17 citations

Lack of biliary excretion of Cd linked to an inherent defect of the canalicular isoform of multidrug resistance protein (cMrp) does not abnormally stimulate accumulation of Cd in the Eisai hyperbilirubinemic (EHB) rat liver

1997 • 11 citations

Accumulation of orally given cadmium in Long-Evans Cinnamon (LEC) rats with an inherently abnormal copper metabolism

1996 • 8 citations

Biliary excretion of mercury and cadmium.

1989 • 3 citations

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