Expression of human glutathione S-transferases in Saccharomyces cerevisiae confers resistance to the anticancer drugs adriamycin and chlorambucil

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Glutathione S-Transferases

1974 • 17,321 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.

1967 • 10,659 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1976 • 4,013 citations

Glutathione Transferases—Structure and Catalytic Activit

1988 • 1,751 citations

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

1979 • 1,179 citations

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

1986 • 791 citations

Mechanism of multidrug resistance

1988 • 630 citations

A family of yeast expression vectors containing the phage f1 intergenic region1

1987 • 514 citations

Expression of anionic glutathione-S-transferase and P-glycoprotein genes in human tissues and tumors.

1989 • 347 citations

[11] Expression of genes in yeast using the ADCI promoter

1983 • 329 citations

Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats.

1986 • 301 citations

Structure and expression of a human class pi glutathione S-transferase messenger RNA.

1987 • 213 citations

Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards.

1985 • 165 citations

Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class mu glutathione transferases and its role in cellular resistance in rat brain tumor cells.

1989 • 165 citations

Characterization of melphalan-glutathione adducts whose formation is catalyzed by glutathione transferases

1986 • 159 citations

Glutathione S-transferases in nitrogen mustard-resistant and -sensitive cell lines.

1987 • 155 citations

Cellular heterogeneity and drug resistance in two ovarian adenocarcinoma cell lines derived from a single patient

1987 • 138 citations

Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards.

1988 • 138 citations

Identification of an anionic form of glutathione transferase present in many human tumors and human tumor cell lines.

1988 • 137 citations

Human placental form of glutathione S-transferase (GST-pi) as a new immunohistochemical marker for human colonic carcinoma.

1986 • 133 citations

Properties of a Yeast Cytochrome P‐450‐Containing Enzyme System which Catalyzes the Hydroxylation of Fatty Acids, Alkanes, and Drugs

1973 • 116 citations

Formation of an adduct between fosfomycin and glutathione: a new mechanism of antibiotic resistance in bacteria

1988 • 115 citations

Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity.

1987 • 113 citations

A proposed mechanism of resistance to cyclophosphamide and phosphoramide mustard in a Yoshida cell line in vitro

1986 • 104 citations

The biochemistry of preneoplastic liver: a common metabolic pattern in hepatocyte nodules

1984 • 101 citations

Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.

1987 • 94 citations

Studies on the Microsomal Electron-transport System of Anaerobically Grown Yeast

1974 • 93 citations

Tumour sulphydryl levels and sensitivity to the nitrogen mustard merophan

1963 • 77 citations

Glutathione S-transferase isoenzymes and glutathione peroxidase activity in normal and tumour samples from human lung

1988 • 73 citations

Glutathione peroxidase, glutathione S-transferase and glutathione reductase activities in normal and neoplastic human breast tissue

1985 • 66 citations

Induction of heat shock gene expression without heat shock by hepatocarcinogens and during hepatic regeneration in rat liver.

1986 • 50 citations

Characterization of the basic glutathione S-transferase B1 and B2 subunits from human liver

1987 • 50 citations

Altered mouse bone marrow glutathione and glutathione transferase levels in response to cytotoxins.

1985 • 45 citations

Purification of acidic glutathione S-transferases from human lung, placenta and erythrocyte and the development of a specific radioimmunoassay for their measurement

1988 • 28 citations

Non-Protein Sulphydryl Group in the Original Strain and Sub-line of the Ascites Tumour resistant to Alkylating Reagents

1960 • 20 citations

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