Nucleo-cytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.

1981 • 725 citations

Nuclear protein localization

1991 • 570 citations

3′-Terminal labelling of RNA with T4 RNA ligase

1978 • 556 citations

How proteins enter the nucleus

1991 • 555 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

Movement of a karyophilic protein through the nuclear pores of oocytes.

1984 • 510 citations

Synthetic peptides as nuclear localization signals

1986 • 472 citations

Structure of spliceosomal snRNPs and their role in pre-mRNA splicing

1990 • 407 citations

Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal

1986 • 394 citations

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

1991 • 391 citations

Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding

1986 • 386 citations

The control of gene expression in animal development

1974 • 369 citations

The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal

1990 • 309 citations

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

1985 • 307 citations

Translocation of RNA-coated gold particles through the nuclear pores of oocytes.

1988 • 292 citations

U2 RNA shares a structural domain with U1, U4, and U5 RNAs.

1982 • 236 citations

An Essential Signaling Role for the m ₃ G Cap in the Transport of U1 snRNP to the Nucleus

1990 • 228 citations

Identification of specific binding proteins for a nuclear location sequence

1989 • 219 citations

Nucleo-cytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap.

1993 • 189 citations

Gamma-monomethyl phosphate: a cap structure in spliceosomal U6 small nuclear RNA.

1989 • 185 citations

Structural organization of ribonucleoproteins containing small nuclear RNAs from HeLa cells

1982 • 184 citations

Intracellular transport of microinjected 5S and small nuclear RNAs

1982 • 162 citations

Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport.

1991 • 144 citations

Purification of snRNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1)RNP antisera.

1983 • 143 citations

Isolation and characterization of rabbit anti-m₃^2,2,7G antibodies

1982 • 135 citations

Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5

1990 • 105 citations

Multiple pathways in nuclear transport: the import of U2 snRNP occurs by a novel kinetic pathway.

1991 • 105 citations

Microinjected U snRNAs are imported to oocyte nuclei via the nuclear pore complex by three distinguishable targeting pathways.

1992 • 93 citations

Nucleocytoplasmic transport and processing of small nuclear RNA precursors.

1990 • 90 citations

Electron microscopy of small nuclear ribonucleoprotein (snRNP) particles U2 and U5: evidence for a common structure-determining principle in the major U snRNP family.

1990 • 78 citations

Reconstitution of the U1 small nuclear ribonucleoprotein particle.

1987 • 72 citations

Electron microscopy of U1 small nuclear ribonucleoprotein particles: shape of the particle and position of the 5′ RNA terminus.

1989 • 51 citations

In vitro reconstitution of U1 and U2 snRNPs from isolated proteins and snRNA

1992 • 47 citations

Nucleocytoplasmic Transport and Processing of Small Nuclear RNA Precursors

1990 • 37 citations

Reconstitution of the Ul Small Nuclear Ribonucleoprotein Particle

1987 • 36 citations

Mutant U2 snRNAs of Xenopus which can form an altered higher order RNA structure are unable to enter the nucleus

1987 • 25 citations

Assembly and nuclear transport of the U4 and U4U6 snRNPs

1992 • 11 citations