Changes in the association of G protein subunits with the cloned mouse delta opioid receptor on agonist stimulation.

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Cloning of a Delta Opioid Receptor by Functional Expression

1992 • 1,225 citations

Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits

1991 • 1,076 citations

The GTP-binding protein, Go9 regulates neuronal calcium channels

1987 • 910 citations

Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

1994 • 630 citations

Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

1993 • 614 citations

Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents

1991 • 576 citations

Morphine receptors as regulators of adenylate cyclase activity.

1975 • 529 citations

Molecular biology of opioid receptors

1993 • 358 citations

Regulation of purified type I and type II adenylylcyclases by G protein beta gamma subunits.

1993 • 290 citations

Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture.

1987 • 266 citations

δ-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2

1990 • 252 citations

Activation of μ opioid receptors inhibits transient high- and low-threshold Ca 2+ currents, but spares a sustained current

1991 • 202 citations

Reconstitution of Somatostatin and Muscarinic Receptor Mediated Stimulation of K⁺Channels by Isolated G_KProtein in Clonal Rat Anterior Pituitary Cell Membranes *

1987 • 188 citations

Thrombin and Phorbol Esters Cause the Selective Phosphorylation of a G Protein Other Than Gi in Human Platelets

1989 • 181 citations

μ and δ opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells

1993 • 174 citations

Differential regulation by cAMP-dependent protein kinase and protein kinase C of the mu opioid receptor coupling to a G protein-activated K+ channel.

1994 • 163 citations

Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2

1993 • 156 citations

Opioids activate both an inward rectifier and a novel voltage-gated potassium conductance in the hippocampal formation

1991 • 145 citations

Opioid Actions on Membrane Ion Channels

1993 • 144 citations

Identification of the subunits of GTP-binding proteins coupled to somatostatin receptors.

1991 • 144 citations

Inhibition of the ω-conotoxin-sensitive calcium current by distinct G proteins

1992 • 128 citations

K‐Opiate Agonists Inhibit Adenylate Cyclase and Produce Heterologous Desensitization in Rat Spinal Cord

1989 • 119 citations

Regulation of Multiple Effectors by the Cloned δ‐Opioid Receptor: Stimulation of Phospholipase C and Type II Adenylyl Cyclase

1995 • 116 citations

Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.

1993 • 111 citations

Identification of the pertussis toxin-sensitive G proteins in platelets, megakaryocytes, and human erythroleukemia cells

1990 • 96 citations

Identification of three separate guanine nucleotide-binding proteins that interact with the delta-opioid receptor in NG108-15 neuroblastoma x glioma hybrid cells.

1992 • 80 citations

Analysis of Gz alpha by site-directed mutagenesis. Sites and specificity of protein kinase C-dependent phosphorylation.

1993 • 77 citations

δ‐ and μ‐opioid receptor mobilization of intracellular calcium in SH‐SY5Y human neuroblastoma cells

1996 • 70 citations

Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells

1991 • 68 citations

Aα-Opiate Receptor in 7315c Tumor Tissue Mediates Inhibition of Immunoreactive Prolactin Release and Adenylate Cyclase Activity

1984 • 60 citations

Gi alpha 1 selectively couples somatostatin receptors to adenylyl cyclase in pituitary-derived AtT-20 cells.

1992 • 58 citations

Analysis of delta-opioid receptor activities stably expressed in CHO cell lines: function of receptor density?

1994 • 54 citations

δ Opioid receptor mediates phospholipase C activation via G_i in Xenopus oocytes

1993 • 50 citations

The G protein beta 2 complementary DNA encodes the beta 35 subunit.

1987 • 47 citations

Immunoprecipitation of alpha 2a-adrenergic receptor-GTP-binding protein complexes using GTP-binding protein selective antisera. Changes in receptor/GTP-binding protein interaction following agonist binding.

1992 • 46 citations

Multiple receptors linked to inhibition of adenylate cyclase accelerate Na+/H+ exchange in neuroblastoma x glioma cells via a mechanism other than decreased cAMP accumulation.

1987 • 36 citations

Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.

1994 • 36 citations

Agonist binding to rat brain somatostatin receptors alters the interaction of the receptors with guanine nucleotide-binding regulatory proteins.

1992 • 30 citations

Activation of mu opioid receptors inhibits transient high- and low-threshold Ca currents, but spares a sustained current

1991 • 29 citations

δ and μ opioid receptor mobilization of intracellular calcium in neuroblastoma cells

1994 • 13 citations