Analysis of Gz alpha by site-directed mutagenesis. Sites and specificity of protein kinase C-dependent phosphorylation.

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations

1991 • 1,036 citations

Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G _q

1991 • 886 citations

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

1991 • 774 citations

G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates.

1990 • 463 citations

The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family

1991 • 373 citations

The rapid formation of inositol phosphates in human platelets by thrombin is inhibited by prostacyclin.

1984 • 319 citations

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

1990 • 282 citations

Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines.

1991 • 278 citations

G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells.

1991 • 263 citations

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.

1988 • 251 citations

G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits.

1991 • 250 citations

1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis.

1985 • 222 citations

A novel complex from bovine visual cells of a 33,000-dalton phosphoprotein with .beta.- and .gamma.-transducin: purification and subunit structure

1987 • 215 citations

Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

1988 • 207 citations

Thrombin and Phorbol Esters Cause the Selective Phosphorylation of a G Protein Other Than Gi in Human Platelets

1989 • 181 citations

Identification of effector-activating residues of Gsα

1992 • 180 citations

Inhibitory action of cyclic GMP on secretion, polyphosphoinositide hydrolysis and calcium mobilization in thrombin-stimulated human platelets

1986 • 136 citations

Lipopolysaccharide response is linked to the GTP binding protein, Gi2, in the promonocytic cell line U937

1989 • 119 citations

Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.

1992 • 110 citations

Identification of the pertussis toxin-sensitive G proteins in platelets, megakaryocytes, and human erythroleukemia cells

1990 • 96 citations

Pheromone-induced phosphorylation of a G protein β subunit in S. cerevisiae is associated with an adaptive response to mating pheromone

1991 • 96 citations

Phosphorylation of Gz in human platelets. Selectivity and site of modification.

1991 • 82 citations

In Vivo Receptor-Mediated Phosphorylation of a G Protein in Dictyostelium

1990 • 55 citations

Cyclic GMP analogs inhibit gamma thrombin-induced arachidonic acid release in human platelets

1989 • 32 citations