Back to search

Sequence Specific Recognition of Double Helical DNA. A Synthetic Approach

Data up to Jan 2025

Published1988
Citations16
References46

Total Citations Per Year

Abstract

References (46)

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

Sequence-Specific Cleavage of Double Helical DNA by Triple Helix Formation

1987 • 1,275 citations

The Molecular Basis of Antibiotic Action

1981 • 1,237 citations

Design of Sequence-Specific DNA-Binding Molecules

1986 • 840 citations

The molecular origin of DNA-drug specificity in netropsin and distamycin.

1985 • 800 citations

Nucleic Acids and Molecular Biology

1994 • 777 citations

Nonintercalating DNA-binding ligands: Specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

1986 • 765 citations

Metals and DNA: Molecular Left-Handed Complements

1986 • 744 citations

Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses

1984 • 477 citations

Binding of an antitumor drug to DNA

1985 • 423 citations

Cleavage of double helical DNA by methidium-propyl-EDTA-iron(II)

1982 • 403 citations

Stereochemistry of actinomycin binding to DNA

1972 • 401 citations

Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG).

1980 • 357 citations

Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II).

1982 • 332 citations

The Molecular Structure of a DNA-Triostin A Complex

1984 • 294 citations

Sequence-specific cleavage of single-stranded DNA: oligodeoxynucleotide-EDTA X Fe(II).

1985 • 243 citations

Molecular recognition of B-DNA by Hoechst 33258

1985 • 227 citations

Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous DNA. Footprinting with methidiumpropyl-EDTA.cntdot.iron(II)

1983 • 218 citations

Echinomycin Binding Sites on DNA

1984 • 218 citations

A comparison of the structure of echinomycin and triostin A complexed to a DNA fragment

1985 • 215 citations

Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural data.

1987 • 185 citations

Methidiumpropyl-EDTA-Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA

1983 • 175 citations

DNA affinity cleaving

1984 • 153 citations

Synthesis of a Sequence-Specific DNA-Cleaving Peptide

1987 • 134 citations

Design synthesis of a sequence-specific DNA cleaving molecule. (Distamycin-EDTA)iron(II)

1982 • 124 citations

Sequence-specific recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s.

1985 • 87 citations

Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA X Fe(II).

1983 • 76 citations

Distamycin and Penta-N-Methylpyrrolecarboxamide Binding Sites on Native DNA A Comparison of Methidiumproyl-EDTA-Fe(II) Footprinting and DNA Affinity Cleaving

1984 • 74 citations

Metalloregulation in the sequence specific binding of synthetic molecules to DNA

1987 • 69 citations

Complementary-Addressed (Sequence-Specific) Modification of Nucleic Acids

1985 • 64 citations

Sequence-specific recognition of B DNA by bis(EDTA-distamycin)fumaramide

1985 • 60 citations

Synthesis of a Site-Specific DNA-Binding Peptide

1987 • 59 citations

Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin.iron(II)) and EDTA-bis(distamycin).iron(II)

1983 • 56 citations

A synthetic peptide binds 16 base pairs of A,T double helical DNA

1987 • 54 citations

Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide

1987 • 52 citations

A new type of AT‐specific ligand constructed of two netropsin‐like molecules

1980 • 38 citations

Footprinting with MPE{middle dot}Fe(II). Complementary-strand Analyses of Distamycin- and Actinomycin-binding Sites on Heterogeneous DNA

1983 • 38 citations

Molecular Mechanisms of Carcinogenic and Antitumor Activity

1987 • 37 citations

Molecular Mechanisms of Carcinogenic and Antitumor Activity.

1989 • 33 citations

Sequence-specific cleavage of double-helical DNA. N-Bromoacetyldistamycin

1985 • 31 citations

Specific sequence-specific recognition of right-handed double-helical DNA by (2S,3S)- and (2R,3R)-dihydroxybis(netropsin)succinamide

1986 • 30 citations

Nonenzymatic sequence-specific cleavage of single-stranded DNA to nucleotide resolution. DNA methyl thioether probes

1987 • 29 citations

New Synthetic Methodology and Functionally Interesting Compounds

1987 • 22 citations

Design of Sequence‐specific DNA Cleaving Molecules

1986 • 5 citations

ChemInform Abstract: Sequence‐Specific Chiral Recognition of Right‐Handed Double‐Helical DNA by (2S,3S)‐ (Ia) and (2R,3R)‐Dihydroxybis(netropsin)succinamide (Ib).

1986 • 4 citations

Design of sequence specific DNA binding molecules: bis(distamycin)phenoxazone

1986 • 2 citations

Cited By (0)

Loading...