Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural data.

The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

1978 • 2,873 citations

Predicting DNA duplex stability from the base sequence.

1986 • 1,800 citations

Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity

1978 • 1,651 citations

Design of Sequence-Specific DNA-Binding Molecules

1986 • 840 citations

The molecular origin of DNA-drug specificity in netropsin and distamycin.

1985 • 800 citations

Nonintercalating DNA-binding ligands: Specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

1986 • 765 citations

Ordered water structure around a B-DNA dodecamer

1983 • 482 citations

Binding of an antitumor drug to DNA

1985 • 423 citations

Salt‐dependent conformational transitions in the self‐complementary deoxydodecanucleotide d(CGCAATTCGCG): Evidence for hairpin formation

1983 • 240 citations

Molecular recognition of B-DNA by Hoechst 33258

1985 • 227 citations

Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution

1982 • 173 citations

Isohelical analysis of DNA groove-binding drugs

1986 • 157 citations

Antibiotic-DNA interactions: intermolecular nuclear Overhauser effects in the netropsin-d(C-G-C-G-A-A-T-T-C-G-C-G) complex in solution.

1982 • 139 citations

Structure and motion: Membranes, nucleic acids and proteins

1986 • 137 citations

A Molecular Basis of Cancer

1983 • 133 citations

Stability of XGCGCp, GCGCYp, and XGCGCYp helixes: an empirical estimate of the energetics of hydrogen bonds in nucleic acids

1986 • 125 citations

Calorimetric and spectroscoptc Investigation of drug - DNA Interactions. I. The binding of netropsin to poly d(AT)

1983 • 93 citations

Sequence-specific recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s.

1985 • 87 citations

Thermodynamics of Drug-DNA Interactions

1983 • 85 citations

Netropsin-poly(dA-dT) complex in solution: structure and dynamics of antibiotic-free base pair regions and those centered on bound netropsin.

1977 • 66 citations

Sequence-dependent recognition of DNA duplexes. Netropsin complexation to the AATT site of the d(G-G-A-A-T-T-C-C) duplex in aqueous solution.

1986 • 62 citations

Netropsin · dG‐dG‐dA‐dA‐dT‐dT‐dC‐dC Complex

1979 • 54 citations

Molecular recognition in noncovalent antitumor agent-DNA complexes: NMR studies of the base and sequence dependent recognition of the DNA minor groove by netropsin

1985 • 46 citations

Nuclear Overhauser Data and Stereochemical Considerations Suggest that Netropsin Binds Symmetrically Within the Minor Groove of Poly(dA)·Poly(dT), Forming Hydrogen Bonds with Both Strands of the Double Helix

1985 • 23 citations

Thermodynamic data for biochemistry and biotechnology

1987 • 23 citations

An optimized differential heat conduction solution microcalorimeter for thermal kinetic measurements

1982 • 20 citations

Base stacking in the dinucleoside phosphate rApA

1978 • 6 citations