I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1996 • 5,498 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

1998 • 1,566 citations

The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide

1995 • 1,512 citations

Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils

1998 • 1,494 citations

Nitric oxide activates cyclooxygenase enzymes.

1993 • 1,416 citations

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

1994 • 1,348 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Blood Flow Regulation by S -Nitrosohemoglobin in the Physiological Oxygen Gradient

1997 • 1,050 citations

Inducible nitric oxide synthase: what difference does it make?

1997 • 964 citations

Nitric oxide and its role in the cardiovascular system

1995 • 598 citations

Accelerated reaction of nitric oxide with O ₂ within the hydrophobic interior of biological membranes

1998 • 590 citations

Reactions between nitric oxide and haemoglobin under physiological conditions

1998 • 577 citations

Essential Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response after Hemorrhagic Shock

1998 • 476 citations

Nitric oxide as an antioxidant

1991 • 441 citations

Modulation of Superoxide-dependent Oxidation and Hydroxylation Reactions by Nitric Oxide

1996 • 355 citations

The Reaction of Nitric Oxide with Organic Peroxyl Radicals

1993 • 318 citations

Metabolic Fate of Peroxynitrite in Aqueous Solution

1997 • 318 citations

Modulation of leukocyte–endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease

1998 • 292 citations

Role of the proteasome and NF-κB in streptococcal cell wall-induced polyarthritis

1998 • 289 citations

Nitric Oxide Regulation of Superoxide and Peroxynitrite-dependent Lipid Peroxidation

1994 • 244 citations

The role of nitric oxide (NO·) in the carcinogenic process

1996 • 225 citations

Superoxide Modulates the Oxidation and Nitrosation of Thiols by Nitric Oxide-derived Reactive Intermediates

1997 • 187 citations

Lack of Tyrosine Nitration by Peroxynitrite Generated at Physiological pH

1998 • 167 citations

[41] Nitric oxide as antiinflammatory agent

1996 • 100 citations

Effect of Nitric Oxide on Hemoprotein-Catalyzed Oxidative Reactions

1998 • 56 citations