Activation of Mac-1 (CD11b/CD18)-bound factor X by released cathepsin G defines an alternative pathway of leucocyte initiation of coagulation

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Structure of Human Des(1-45) Factor Xa at 2·2 Å Resolution

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The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor.

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Adhesive receptor Mac-1 coordinates the activation of factor X on stimulated cells of monocytic and myeloid differentiation: an alternative initiation of the coagulation protease cascade.

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Leukocyte Elastase Release during Blood Coagulation

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CD11b/CD18 (Mac-1) is required for degranulation of human eosinophils induced by human recombinant granulocyte-macrophage colony-stimulating factor and platelet-activating factor.

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Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity.

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Cathepsin G is a strong platelet agonist released by neutrophils

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Characterization of an almost full-length cDNA coding for human blood coagulation factor X.

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Human Coagulation Factor V Is Activated to the Functional Cofactor by Elastase and Cathepsin G Expressed at the Monocyte Surface

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Human leukocyte elastase, cathepsin G, and lactoferrin: family of neutrophil granule glycoproteins that bind to an alveolar macrophage receptor.

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Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors

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Neutrophil cathepsin G modulates the platelet surface expression of the glycoprotein (GP) Ib-IX complex by proteolysis of the von Willebrand factor binding site on GPIb alpha and by a cytoskeletal-mediated redistribution of the remainder of the complex

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Factor Xa interacts with two sites on monocytes with different functional activities

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Human Leukocyte Elastase and Cathepsin G Inactivate Factor VII by Limited Proteolysis

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Degradation of Human Factor X by Human Polymorphonuclear Leucocyte Cathepsin G and Elastase

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Cathepsin G activates human factor V in vitro

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