Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

The preparation and properties of two new chromogenic substrates of trypsin

1961 • 3,319 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

Tetranitromethane. A Reagent for the Nitration of Tyrosyl Residues in Proteins^*

1966 • 635 citations

Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site.

1979 • 602 citations

Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues

1975 • 385 citations

Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases.

1982 • 298 citations

Susceptibility of soluble and matrix fibronectins to degradation by tissue proteinases, mast cell chymase and cathepsin G.

1981 • 256 citations

Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G Inhibition with peptide chloromethyl ketones

1977 • 224 citations

The degradation of articular collagen by neutrophil proteinases

1977 • 189 citations

Human α-1-antichymotrypsin: interaction with chymotrypsin-like proteinases

1978 • 174 citations

The degradation of cartilage proteoglycans by tissue proteinases. Proteoglycan structure and its susceptibility to proteolysis

1977 • 156 citations

Human cathepsin G. Catalytic and immunological properties

1976 • 140 citations

The degradation of human lung elastin by neutrophil proteinases

1980 • 129 citations

Stimulation of the elastolytic activity of leukocyte elastase by leukocyte cathepsin G.

1981 • 118 citations

The granulocyte-angiotensin system. Angiotensin I-converting activity of cathepsin G.

1982 • 107 citations

Identification of a human neutrophil angiotension II-generating protease as cathepsin G.

1982 • 105 citations

The acetylation of insulin

1971 • 102 citations

Substrate specificity of the elastase and the chymotrypsin-like enzyme of the human granulocyte

1977 • 99 citations

Modification of carboxyl groups in bovine carboxypeptidase A. I. Inactivation of the enzyme by N-ethyl-5-phenylisoxazolium-3'-sulfonate (Woodward's reagent K)

1971 • 98 citations

Studies on reactivity of human leukocyte elastase, cathepsin G, and porcine pancreatic elastase toward peptides including sequences related to the reactive site of .alpha.1-protease inhibitor (.alpha.1-antitrypsin)

1980 • 97 citations

Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin A.alpha., and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates

1984 • 91 citations

A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates.

1982 • 87 citations

Granulocyte-angiotensin system. Identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G

1984 • 83 citations

Substrate specificity of two chymotrypsin-like proteases from rat mast cells. Studies with peptide 4-nitroanilides and comparison with cathepsin G

1980 • 73 citations

Amino acid sequence at the reactive site of human alpha 1-antichymotrypsin.

1983 • 70 citations

Reaction of azapeptides with chymotrypsin-like enzymes. New inhibitors and active site titrants for chymotrypsin A alpha, subtilisin BPN', subtilisin Carlsberg, and human leukocyte cathepsin G.

1984 • 68 citations

Reactivity of human leukocyte elastase and porcine pancreatic elastase toward peptide-4-nitroanilides containing model desmosine residues. Evidence that human leukocyte elastase is selective for crosslinked regions of elastin

1981 • 62 citations

A study of renaturation of reduced hen egg white lysozyme. Enzymically active intermediates formed during oxidation of the reduced protein.

1976 • 60 citations

Identification of proteinases in rheumatoid synovium detection of luekocyte elastase cathepsin G and another serine proteinase

1980 • 60 citations

Inhibition of elastase and other serine proteases by heterocyclic acylating agents.

1980 • 56 citations

Identification of neutral proteases in human neutrophil granules that degrade articular cartilage proteoglycan

1975 • 46 citations

Interaction of the chymotrypsin- and elastase-like enzymes of the human granulocyte with glycosaminoglycans

1981 • 46 citations

Specificity and reactivity of human leukocyte elastase, porcine pancreatic elastase, human granulocyte cathepsin G, and bovine pancreatic chymotrypsin with arylsulfonyl fluorides. Discovery of a new series of potent and specific irreversible elastase inhibitors.

1982 • 46 citations

The inhibition of human leucocyte elastase and chymotrypsin-like protease by elastatinal and chymostatin

1976 • 44 citations

Action of human cathepsin G on the oxidized B chain of insulin

1977 • 38 citations

Effect of Neutrophil Cathepsin G on Elastin Degradation by Neutrophil Elastase

1984 • 35 citations

Reaction of peptide thiobenzyl esters with mammalian chymotrypsinlike enzymes: A sensitive assay method

1981 • 33 citations

Importance of secondary enzyme-substrate interactions in human cathepsin G and chymotrypsin II catalysis

1981 • 27 citations

Cleavage of fibrinogen by the human neutrophil neutral peptide-generating protease.

1980 • 23 citations

Cathepsin G from human polymorphonuclear leukocytes cleaves human IgM

1982 • 23 citations

Chymotrypsin-like Neutral Protease from Lysosomes of Human Polymorphonuclear Leukocytes

1977 • 22 citations

Cleavage of the Four Human IgG Subclasses with Cathepsin G

1982 • 20 citations

Degradation of human fibrinogen by chymotrypsin-like neutral protease from human granulocytes

1980 • 15 citations

The digestion of the oxidized B chain of insulin by human neutrophile proteases: Elastase and chymotrypsin-like protease

1979 • 13 citations