Human Coagulation Factor V Is Activated to the Functional Cofactor by Elastase and Cathepsin G Expressed at the Monocyte Surface

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

The contribution of bovine Factor V and Factor Va to the activity of prothrombinase.

1979 • 592 citations

COFACTOR PROTEINS IN THE ASSEMBLY AND EXPRESSION OF BLOOD CLOTTING ENZYME COMPLEXES

1988 • 535 citations

Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator.

1986 • 390 citations

Factor X activating enzyme from Russell's viper venom: isolation and characterization

1976 • 387 citations

Progress in Hemostasis and Thrombosis.

1974 • 349 citations

Identification and distribution of fibrinogen, fibrin, and fibrin(ogen) degradation products in atherosclerosis. Use of monoclonal antibodies.

1989 • 269 citations

The Size and Shape of Human and Bovine Antithrombin III

1977 • 264 citations

Activation of human factor V by factor Xa and thrombin

1990 • 252 citations

Radioimmunoassay of factor V in human plasma and platelets

1982 • 246 citations

Radioimmunoassay of factor V in human plasma and platelets

1982 • 225 citations

A Simplified Procedure for Purification of Human Prothrombin, Factor IX and Factor X

1981 • 222 citations

Chemotactic response of monocytes to thrombin.

1983 • 221 citations

Isolation of functional human coagulation factor V by using a hybridoma antibody.

1981 • 208 citations

Proteolytic cleavage and inactivation of alpha 2-plasmin inhibitor and C1 inactivator by human polymorphonuclear leukocyte elastase.

1982 • 207 citations

Fate of fibrinogen in human arterial intima.

1990 • 202 citations

Chemistry and biology of thrombin

1978 • 198 citations

Human prothrombinase complex assembly and function on isolated peripheral blood cell populations.

1985 • 196 citations

Isolation of human T and B lymphocytes by rosette formation with 2-aminoethylisothiouronium bromide (AET) — Treated sheep red blood cells and with monkey red blood cells

1976 • 187 citations

Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity.

1989 • 185 citations

Evidence for the formation of an ester between thrombin and heparin cofactor

1975 • 180 citations

Identification and distribution of fibrinogen, fibrin and fibrin (ogen) degradation products in atherosclerosis

1989 • 168 citations

Activation/inactivation of human factor V by plasmin

1989 • 159 citations

Kinetics of inactivation of membrane-bound factor Va by activated protein C. Protein S modulates factor Xa protection.

1988 • 158 citations

Role of the clotting system in cell-mediated hypersensitivity. II. Kinetics of fibrinogen/fibrin accumulation and vascular permeability changes in tuberculin and cutaneous basophil hypersensitivity reactions.

1975 • 147 citations

Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation

1979 • 140 citations

Functional prothrombinase complex assembly on isolated monocytes and lymphocytes.

1983 • 139 citations

The factor Xa-catalyzed activation of factor V.

1983 • 132 citations

The effect of leukocyte elastase on tissue factor pathway inhibitor

1992 • 130 citations

Progress in Hemostasis and Thrombosis.

1983 • 124 citations

[11] The activation of bovine coagulation factor X

1976 • 124 citations

Elastase-mediated fibrinogenolysis by chemoattractant-stimulated neutrophils occurs in the presence of physiologic concentrations of antiproteinases.

1987 • 123 citations

Effect of Human Granulocytic Elastase on Isolated Human Antithrombin III

1981 • 122 citations

Effect of elastase-like and chymotrypsin-like neutral proteases from human granulocytes on isolated clotting factors

1975 • 118 citations

Chemistry and biology of thrombin

1977 • 116 citations

Activation of prothrombin with (taipan snake) venom

1973 • 107 citations

Heparin Promotes the Inactivation of Antithrombin by Neutrophil Elastase

1987 • 104 citations

Enhancement of cathepsin G-induced platelet activation by leukocyte elastase: consequence for the neutrophil-mediated platelet activation

1993 • 95 citations

Role of the Clotting System in Cell-Mediated Hypersensitivity

1975 • 91 citations

Effect of Leukocyte Proteinases on Tissue Factor Pathway Inhibitor

1992 • 86 citations

Extracellular Matrix Injury during Lung Inflammation

1987 • 85 citations

Protein C Degradation in vitro by Neutrophil Elastase

1991 • 72 citations

An elastase-dependent pathway of plasminogen activation

1989 • 70 citations

Functional difference between intrinsic and extrinsic coagulation pathways. Kinetics of factor X activation on human monocytes and alveolar macrophages

1991 • 65 citations

The structural basis for neutrophil inactivation of C1̅ inhibitor

1989 • 62 citations

Activation of Coagulation Factor V by a Platelet Protease

1982 • 52 citations

Functional features of lymphocytes recovered from a human renal allograft

1973 • 51 citations

Sequential receptor cascade for coagulation proteins on monocytes

1989 • 46 citations

Elastase and cathepsin G of human monocytes: heterogeneity and subcellular localization to peroxidase-positive granules.

1990 • 43 citations

Cleavage and inactivation of Factor IX by granulocyte elastase.

1983 • 33 citations

Effects of Neutral Proteases from Human Leukocytes on Structure and Biological Properties of Human Factor VIII

1980 • 31 citations

Neutrophil Elastase Potentiates Cathepsin G-lnduced Platelet Activation

1992 • 31 citations

Inactivation of heparin cofactor II by polymorphonuclear leukocytes

1987 • 29 citations

Protein S degradationin vitroby neutrophil elastase

1993 • 24 citations

Factor Xa interacts with two sites on monocytes with different functional activities

1992 • 21 citations

Identification of elastases associated with purified plasma membranes isolated from human monocytes and lymphocytes

1983 • 20 citations

FVIIa derivatives obtained by autolytic and controlled cathepsin G mediated cleavage

1993 • 16 citations

The degradation of bovine and human prothrombin by human polymorphonuclear leukocyte cathepsin g

1986 • 15 citations

The regulation of human factor V by a neutrophil protease

1987 • 14 citations