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2000 • 4,644 citations

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MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances

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Essential function for the kinase TAK1 in innate and adaptive immune responses

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Defective B cell development and function in Btk-deficient mice

1995 • 729 citations

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

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The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes

2004 • 674 citations

Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

2001 • 551 citations

Essential Role of LAT in T Cell Development

1999 • 537 citations

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

2003 • 524 citations

Monomeric IgE Stimulates Signaling Pathways in Mast Cells that Lead to Cytokine Production and Cell Survival

2001 • 408 citations

Mast Cells Control Neutrophil Recruitment during T Cell–Mediated Delayed-Type Hypersensitivity Reactions through Tumor Necrosis Factor and Macrophage Inflammatory Protein 2

2000 • 384 citations

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation

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Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

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Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase

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The diverse potential effector and immunoregulatory roles of mast cells in allergic disease

2000 • 361 citations

LAT Is Essential for FcεRI-Mediated Mast Cell Activation

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Regulation of Mast Cell Survival by IgE

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Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells.

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Mast cells enhance T cell activation: Importance of mast cell-derived TNF

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Emerging and diverse roles of protein kinase C in immune cell signalling

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Substance P induces TNF-α and IL-6 production through NFκB in peritoneal mast cells

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Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells

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Molecular adapters in FcεRI signaling and the allergic response

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Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells.

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SHIP Negatively Regulates IgE + Antigen-Induced IL-6 Production in Mast Cells by Inhibiting NF-κB Activity

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Dependence of mast cell IgE-mediated cytokine production on nuclear factor-κB activity

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Protein Kinase C-δ Is a Negative Regulator of Antigen-Induced Mast Cell Degranulation

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Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cβ

2000 • 125 citations

Role of activator protein 1, nuclear factor-κB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells

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Equine Herpesvirus-2 E10 Gene Product, but Not Its Cellular Homologue, Activates NF-κB Transcription Factor and c-Jun N-terminal Kinase

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Regulation of protein kinase CβI by two protein-tyrosine kinases, Btk and Syk

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Protein kinase Cδ functions downstream of Ca2+ mobilization in FcεRI signaling to degranulation in mast cells

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Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IκB-NF-κB pathway in IgE-dependent mast cell activation

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An Immunopharmacological Study of the Biphasic Allergic Skin Reaction in Mice.

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Protein kinase C‐α mediates TNF release process in RBL‐2H3 mast cells

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Homologous Passive Cutaneous Anaphylaxis in Various Strains of Mice

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Equine Herpesvirus Protein E10 Induces Membrane Recruitment and Phosphorylation of Its Cellular Homologue, Bcl-10

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