Influence of polyamines on membrane functions

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

POLYAMINES

1984 • 2,996 citations

Membrane Fusion

1990 • 2,458 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Polyamine metabolism and function

1982 • 1,649 citations

Recent advances in the biochemistry of polyamines in eukaryotes

1986 • 1,587 citations

Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy.

1988 • 1,533 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

Role of Polyamines in the Control of Cell Proliferation and Differentiation

1981 • 935 citations

Calcium messenger system: an integrated view.

1984 • 916 citations

Introduction to the polyamines

1971 • 682 citations

Counterion-induced condensation of deoxyribonucleic acid. A light-scattering study

1979 • 621 citations

SPERMIDINE, SPERMINE, AND RELATED AMINES.

1964 • 547 citations

The physiology and biochemistry of polyamines in plants

1984 • 513 citations

[The role of protein kinase C in cell surface signal transduction and tumor promotion].

1986 • 508 citations

Protein kinase C activation by diacylglycerol second messengers

1986 • 498 citations

"Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells?

1988 • 451 citations

Inositol 1,4,5-trisphosphate: a possible chemical link in excitation-contraction coupling in muscle.

1985 • 330 citations

Purification and characterization of two immunologically distinct phosphoinositide-specific phospholipases C from bovine brain.

1987 • 243 citations

Polyamines regulate calcium fluxes in a rapid plasma membrane response

1983 • 225 citations

Polyamines Inhibit Biosynthesis of Ethylene in Higher Plant Tissue and Fruit Protoplasts

1981 • 215 citations

Handbook of Neurochemistry

1983 • 187 citations

INHIBITION BY NEOMYCIN OF POLYPHOSPHOINOSITIDE TURNOVER IN SUBCELLULAR FRACTIONS OF GUINEA‐PIG CEREBRAL CORTEX IN VITRO

1976 • 182 citations

Spermine. A regulator of mitochondrial calcium cycling.

1984 • 181 citations

Stabilization of Oat Leaf Protoplasts through Polyamine-mediated Inhibition of Senescence

1977 • 178 citations

Biosynthesis and Metabolism of 1,4‐diaminobutane, Spermidine, Spermine, and Related Amines

1972 • 173 citations

Modulation of membrane protein lateral mobility by polyphosphates and polyamines

1980 • 173 citations

Talking point Amphitropic proteins: a new class of membrane proteins

1988 • 168 citations

Restriction of the lateral motion of band 3 in the erythrocyte membrane by the cytoskeletal network: dependence on spectrin association state

1986 • 167 citations

Polyamine inhibition of lipoperoxidation. The influence of polyamines on iron oxidation in the presence of compounds mimicking phospholipid polar heads

1988 • 166 citations

Surface Charge of Biological Membranes as a Possible Regulator of Membrane‐Bound Enzymes

1979 • 165 citations

Brain Hexokinase, the Prototype Ambiquitous Enzyme

1980 • 162 citations

Inhibition by polyamines of lipid peroxide formation in rat liver microsomes

1979 • 162 citations

Membrane fusion: Lipid vesicles as a model system

1986 • 147 citations

Polyamine starvation causes disappearance of actin filaments and microtubules in polyamine-auxotrophic CHO cells

1981 • 142 citations

Adsorption of cations to phosphatidylinositol 4,5-bisphosphate

1988 • 137 citations

Characterization of D-myo-inositol 1,4,5-trisphosphate phosphatase in rat liver plasma membranes.

1984 • 131 citations

Bovine brain contains two types of phosphatidylinositol kinase

1987 • 125 citations

Interaction of gentamicin and spermine with bilayer membranes containing negatively charged phospholipids

1985 • 124 citations

Interaction between polyamines and nucleic acids or phospholipids

1982 • 112 citations

Stabilization of erythrocyte membranes by polyamines.

1983 • 111 citations

Polyamines appear to be second messengers in mediating Ca2+ fluxes and neurotransmitter release in potassium-depolarized synaptosomes

1985 • 107 citations

Inhibition of polyamine metabolism

1988 • 106 citations

Polyamines inhibit phospholipid-sensitive and calmodulin-sensitive Ca2+-dependent protein kinases

1983 • 103 citations

The stabilizing effect of spermine and related polyamines and bacterial protoplasts

1959 • 101 citations

STABILIZATION OF PROTOPLASTS AND SPHEROPLASTS BY SPERMINE AND OTHER POLYAMINES

1962 • 99 citations

Control of exocytosis

1987 • 98 citations

Drug-induced Ca2+ release from isolated sarcoplasmic reticulum. III. Block of Ca2+-induced Ca2+ release by organic polyamines.

1987 • 94 citations

Identification of the protein 4.1 binding site to phosphatidylserine vesicles

1988 • 94 citations

Effects of Exogenous 1,3-Diaminopropane and Spermidine on Senescence of Oat Leaves

1982 • 92 citations

Polyamines as modulators of membrane fusion: aggregation and fusion of liposomes

1983 • 88 citations

Beta-adrenergic stimulation of Ca2+ fluxes, endocytosis, hexose transport, and amino acid transport in mouse kidney cortex is mediated by polyamine synthesis.

1983 • 83 citations

Spermine as a modulator of membrane fusion: interactions with acidic phospholipids

1986 • 81 citations

Interactions between polyamines and nucleotides

1977 • 80 citations

Polyamines Stimulate Mitochondrial Calcium Transport in Rat Brain

1987 • 76 citations

Interactions between spermine and Mg2+ on mitochondrial Ca2+ transport.

1986 • 76 citations

Calpactin in exocytosis?

1988 • 76 citations

Membrane Fusion

1985 • 74 citations

Inhibition of phospholipase A2 and phospholipase C by polyamines

1978 • 69 citations

Polyamine binding to phospholipid vesicles and inhibition of lipid peroxidation

1984 • 68 citations

Effects of cations and polyamines on the aggregation and fusion of phosphatidylserine membranes

1986 • 61 citations

Uptake of spermine by rat liver mitochondria and its influence on the transport of phosphate

1985 • 60 citations

Catalytic properties of a purified phosphatidylinositol-4-phosphate kinase from rat brain

1986 • 59 citations

ESR studies of the erythrocyte membrane skeletal protein network: Influence of the state of aggregation of spectrin on the physical state of membrane proteins, bilayer lipids, and cell surface carbohydrates

1985 • 58 citations

Regulatory effects of polyamines on membrane-bound acetylcholinesterase

1974 • 57 citations

Polylysine-containing peptides, including the carboxyl-terminal segment of the human c-Ki-ras 2 protein, affect the activity of some key membrane enzymes.

1987 • 57 citations

Polyamines Biological modulators of membrane fusion

1983 • 55 citations

An inhibitory role for polyamines in protein kinase C activation and insulin secretion in mouse pancreatic islets

1986 • 54 citations

Growth signal transduction: Rapid activation of covalently bound ornithine decarboxylase during phosphatidylinositol breakdown

1987 • 53 citations

Hepatic lipid metabolism: Effect of spermine, albumin, and Z protein on microsomal lipid formation

1979 • 53 citations

Electron spin resonance and biochemical studies of the interaction of the polyamine, spermine, with the skeletal network of proteins in human erythrocyte membranes

1988 • 53 citations

Effects of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on testosterone-induced regeneration of prostate and seminal vesicle in castrated rats

1979 • 52 citations

Inhibitory action of polyamines on protein kinase C association to membranes

1987 • 49 citations

Progress in polyamine research : novel biochemical, pharmacological, and clinical aspects

1988 • 46 citations

Polyamines stimulate the phosphorylation of phosphatidylinositol in membranes from A 431 cells

1986 • 44 citations

Interaction of spermine with polyphosphoinositides containing liposomes and myo-inositol 1,4,5 triphosphate

1986 • 44 citations

The effects of polyamines and aminoglycosides on phosphatidylinositol-specific phospholipase C from human amnion

1983 • 42 citations

In vitro response of rat and human kidney lysosomes to aminoglycosides

1982 • 42 citations

Restorative effects of spermine on oxidative phosphorylation and respiration in heat-aged mitochondria

1982 • 42 citations

A Possible Mechanism of Protection by Polyamines against Gastric Damage Induced by Acidified Ethanol in Rats: Polyamine Protection May Depend on Its Antiperoxidative Properties

1987 • 40 citations

Regulation of <scp>l</scp>-ornithine decarboxylase and S-adenosyl-<scp>l</scp>-methionine decarboxylase in rat ventral prostate and seminal vesicle

1977 • 40 citations

The binding of polyamines to phospholipid bilayers

1986 • 39 citations

Impairment of macrophage function by inhibitors of ornithine decarboxylase activity

1987 • 39 citations

Polyamines are intracellular messengers in the β-adrenergic regulation of Ca2+ fluxes, [Ca2+]i and membrane transport in rat heart myocytes

1988 • 38 citations

Rapid activation of ornithine decarboxylase by mitogenic (but not by nonmitogenic) ligands in human T lymphocytes

1985 • 38 citations

Role of G-proteins in T cell activation: non-hydrolysable GTP analogues induce early ornithine decarboxylase activity in human T lymphocytes.

1986 • 38 citations

Phosphatidylinositol-4-phosphate kinase from rat brain. Activation by polyamines and inhibition by phosphatidylinositol 4,5-bisphosphate

1986 • 37 citations

STABILIZATION OF STREPTOCOCCUS FAECALIS PROTOPLASTS BY SPERMINE

1964 • 36 citations

Spermine promotes the translocation of phosphatidate phosphohydrolase from the cytosol to the microsomal fraction of rat liver and it enhances the effects of oleate in this respect

1985 • 36 citations

Effect of salts on membrane binding and activity of adipocyte phosphatidate phosphohydrolase

1982 • 35 citations

Effect of basic compounds on the polymerization of clathrin

1981 • 35 citations

Activation of rat liver choline kinase by polyamines

1976 • 34 citations

Effect of polyamines on the metabolism of [16-14C]estradiol by rat-liver microsomes

1967 • 34 citations

Effects of Polyamines on Calcium‐Dependent Rat Brain Phosphatidylinositol‐Phosphodiesterase

1981 • 33 citations

Inhibition of the bioenergetic functions of isolated rat liver mitochondria by polyamines

1982 • 33 citations

Effect of polyamines on the electrokinetic properties of red blood cells

1976 • 32 citations

Cationic activation of galactosyltransferase from rat mammary Golgi membranes by polyamines and by basic peptides and proteins

1986 • 32 citations

Glycerolipid biosynthesis in rat adipose tissue effect of polyamines on triglyceride synthesis

1977 • 30 citations

Polyamines are inhibitors of gastric acid secretion.

1982 • 30 citations

Inhibition of Na,K-ATPase from Chick Brain by Polyamines

1977 • 29 citations

Inhibition of phosphoinositide metabolism in human polymorphonuclear leukocytes by S-adenosylhomocysteine.

1988 • 29 citations

Fluorescence polarization studies on Escherichia coli membrane stability and its relation to the resistance of the cell to freeze-thawing. II. Stabilization of the membranes by polyamines

1986 • 29 citations

Effects of Polyamines on the Uptake of Neurotransmitters by Rat Brain Synaptosomes

1984 • 27 citations

Adenosine cyclic 3',5'-monophosphate-dependent protein kinase and ornithine decarboxylase involvement in the induction of cytochrome P-450 and hepatic hypertrophy.

1976 • 27 citations

Activation of the ADP/ATP carrier from mitochondria by cationic effectors

1986 • 27 citations

Activation of phosphatidylinositol-4-phosphate kinase in rat liver plasma membranes by polyamines

1987 • 26 citations

Polyamines stimulate d-glucose transport in isolated renal brush-border membrane vesicles

1984 • 26 citations

Fluorescence formation from hydroperoxide of phosphatidylcholine with amino compound

1988 • 25 citations

Effects of polyamines on partial reactions of membrane

1978 • 22 citations

Effect of Exogenous Putrescine, Spermidine, and Spermine on K⁺ Uptake and H⁺ Extrusion through Plasmamembrane in Maize Root Segments

1988 • 22 citations

Inhibitory activity of polyamines on phospholipase C from human platelets

1982 • 22 citations

Spermine binding to submitochondrial particles and activation of adenosine triphosphatase

1984 • 22 citations

IMIPRAMINE‐INDUCED CHANGES OF BRAIN ADENOSINE TRIPHOSPHATASE ACTIVITY

1973 • 21 citations

Enhancement of UDP-galactose:Mucin galactosyltransferase activity by spermine

1974 • 20 citations

Activation of Na+-K+-adenosine triphosphatase by spermine

1978 • 19 citations

Ornithine decarboxylase activity and: [125I]iododeoxyuridine incorporation in rat prostate

1975 • 19 citations

Glycerolipid biosynthesis in rat adipose tissue

1983 • 18 citations

Polyamine-polyphosphate complexes as enzyme inhibitors

1980 • 17 citations

Specific effects of spermine on ouabain-sensitive and potassium-dependent phosphatase activity of kidney plasma membranes Specificity of the potassium sites

1977 • 17 citations

Polyamines-sickling red blood cell interaction

1977 • 16 citations

Differential effects of spermine on aggregation, inositol phosphate formation and protein phosphorylation in human platelets in response to thrombin, arachidonic acid and lysophosphatidic acid

1986 • 16 citations

Stimulation of glucose-6-phosphatase by polyamines is a membrane-mediated event

1980 • 15 citations

Effect of polyamines on prostaglandin synthesis in various cell-free systems

1981 • 15 citations

Role of spermidine in the activity of sn-glycerol-3-phosphate acyltransferase from Escherichia coli

1982 • 15 citations

Induction of polyamine limitation in Chinese hamster ovary cells by α‐methylornithine

1981 • 14 citations

Polyamines as modulators of drug oxidation reactions catalyzed by cytochrome P-450 from liver microsomes

1983 • 14 citations

Inhibitory action of spermidine on formyl-methionyl-leucyl-phenylalanine stimulated inositol phosphate production in human neutrophils

1987 • 13 citations

Polyamines effect on subcellular fractionation of rat liver homogenate

1980 • 12 citations

Polyamines and the catalytic domain of protein kinase C

1988 • 12 citations

Action of spermine on phosphate transport in liver mitochondria

1986 • 12 citations

Spermidine and spermine stimulate the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria

1987 • 11 citations

Specific Effects of Spermine on Na+, K+-Adenosine Triphosphatase1

1981 • 11 citations

Polyamines stimulate lysosomal cystine transport.

1987 • 11 citations

Polyamines and drug oxidations.

1976 • 10 citations

Effects of spermine and albumin on hepatic mitochondrial and microsomal glycerol phosphate acyltransferase activities

1981 • 9 citations

Influence of polyamines on two bivalent-cation-activated ATPases.

1973 • 9 citations

Translation of an RNA viral message in vitro: One-step polypeptide chain elongation

1971 • 9 citations

The influence of poly(ethylene glycol) 6000 on spermine-induced aggregation of liposomes

1986 • 8 citations

Interaction of basic compounds with coated vesicles

1984 • 8 citations

Modification of the cardiac transmembrane potentials and currents by polyamines

1987 • 6 citations

Effect of spermine on the translocation of Mg2+-dependent phosphatidate phosphohydrolase

1987 • 5 citations

Influence of Spermine on Some Membrane-disturbing Actions

1975 • 5 citations

Inhibition of polyamine synthesis blocks urinary secretion of β-glucuronidase from mouse kidney

1983 • 4 citations

[Effect of polyamines on mitochondrial membranes: studies with fluorescent probes].

1976 • 1 citations

[Interactions of polyamines with mitochondrial membranes: study with fluorescence polarization].

1976 • 1 citations