Differential effects of spermine on aggregation, inositol phosphate formation and protein phosphorylation in human platelets in response to thrombin, arachidonic acid and lysophosphatidic acid

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

1980 • 1,317 citations

Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol

1983 • 1,104 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

The rapid formation of inositol phosphates in human platelets by thrombin is inhibited by prostacyclin.

1984 • 319 citations

Inositol 1,4,5-trisphosphate releases Ca2+ from a Ca2+-transporting membrane vesicle fraction derived from human platelets.

1985 • 268 citations

Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.

1983 • 205 citations

Complex formation of platelet thrombospondin with fibrinogen.

1982 • 195 citations

Purification and preliminary physicochemical characterization of human platelet membrane glycoprotein V.

1981 • 137 citations

Platelet thrombin receptors. Binding of alpha-thrombin is coupled to signal generation by a chymotrypsin-sensitive mechanism.

1980 • 82 citations

The role of phospholipase C in platelet responses

1983 • 79 citations

Mepacrine (quinacrine) inhibition of thrombin-induced platelet responses can be overcome by lysophosphatidic acid

1985 • 37 citations

Activation of permeabilized platelets by inositol-1, 4, 5-trisphosphate

1985 • 31 citations

Lysophosphatidic acid can activate platelets without increasing 32P-labelling of phosphatidic acid

1984 • 30 citations

The influence of amines on various platelet responses

1983 • 27 citations

Inhibition of platelet aggregation and endogenous lectin activity by oligoamines

1984 • 24 citations

Inhibitory activity of polyamines on phospholipase C from human platelets

1982 • 22 citations

Inhibition of platelet aggregation by primary amines. Evidence for a possible role of membrane-associated calcium

1982 • 15 citations