Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

1990 • 3,134 citations

Male development of chromosomally female mice transgenic for Sry

1991 • 2,157 citations

WT-1 is required for early kidney development

1993 • 1,976 citations

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

1990 • 1,630 citations

A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation

1994 • 1,604 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

Cell Biology: a Laboratory Handbook

1995 • 1,226 citations

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 • 1,138 citations

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

1997 • 1,031 citations

Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

1986 • 997 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

The candidate Wilms' tumour gene is involved in genitourinary development

1990 • 884 citations

Expression of a candidate sex-determining gene during mouse testis differentiation

1990 • 834 citations

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds

1996 • 788 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart.

1993 • 708 citations

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

1997 • 660 citations

Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases.

1994 • 589 citations

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

1994 • 567 citations

Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: A link to the sex determination cascade

1994 • 562 citations

Embryonic expression of a haematopoietic growth factor encoded by the SI locus and the ligand for c-kit

1990 • 521 citations

An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

1988 • 518 citations

Expression of the Wilms' tumor gene WT1 in the murine urogenital system.

1991 • 447 citations

GATA transcription factors: key regulators of hematopoiesis.

1995 • 430 citations

Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function

1996 • 404 citations

Physiology of Reproduction.

1972 • 354 citations

Genetic analysis of the Müllerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation.

1996 • 354 citations

Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development.

1991 • 346 citations

Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development.

1996 • 303 citations

The Expression Pattern of the c-kit Ligand in Gonads of Mice Supports a Role for the c-kit Receptor in Oocyte Growth and in Proliferation of Spermatogonia

1993 • 303 citations

Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis

1993 • 301 citations

In situ analysis of fetal, prepuberal and adult XX ↔ XY chimaeric mouse testes: Sertoli cells are predominantly, but not exclusively, XY

1991 • 293 citations

A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription.

1994 • 271 citations

Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells.

1995 • 263 citations

Molecular basis of mammalian sexual determination: activation of Mullerian inhibiting substance gene expression by SRY

1994 • 260 citations

Rescue of erythroid development in gene targeted GATA–1− mouse embryonic stem cells

1992 • 258 citations

Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells

1994 • 242 citations

Expression and Hormonal Regulation of Transcription Factors GATA-4 and GATA-6 in the Mouse Ovary¹

1997 • 204 citations

The nuclear receptor SF-1 mediates sexually dimorphic expression of Müllerian Inhibiting Substance, in vivo

1997 • 196 citations

Mouse GATA-4: a Retinoic Acid-Inducible GATA-Binding Transcription Factor Expressed in Endodermally Derived Tissues and Heart

1993 • 181 citations

Inhibition of Transcription Factor GATA-4 Expression Blocks In Vitro Cardiac Muscle Differentiation

1995 • 175 citations

SRY recognizes conserved DNA sites in sex-specific promoters.

1993 • 151 citations

Ontogeny of follicle-stimulating hormone receptor gene expression in the rat testis and ovary

1995 • 146 citations

Chromosome Mapping and Expression of a Putative Testis-Determining Gene in Mouse

1989 • 146 citations

Expression of the mRNA for the ligand of C-kit in mouse sertoli cells

1991 • 130 citations

Hormonal and developmental regulation of DAX-1 expression in Sertoli cells.

1996 • 128 citations

Testicular Expression of Inhibin and Activin Subunits and Follistatin in the Rat and Human Fetus and Neonate and During Postnatal Development in the Rat¹

1997 • 113 citations

Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells.

1994 • 109 citations

Gastric DNA-binding proteins recognize upstream sequence motifs of parietal cell-specific genes.

1993 • 101 citations

Expression of follicle stimulating hormone-receptor mRNA during gonadal development

1996 • 91 citations

Immunostainable Inhibin Subunits Are in Multiple Types of Testicular Cells*

1989 • 85 citations

A Hormone-Encoding Gene Identifies a Pathway for Cardiac but Not Skeletal Muscle Gene Transcription

1994 • 75 citations

Synergistic effects of inhibins and müllerian-inhibiting substance on testicular tumorigenesis.

1995 • 73 citations

Characterization of the Promoter of SF-1, an Orphan Nuclear Receptor Required for Adrenal and Gonadal Development

1997 • 71 citations

Expression of the gene for anti-Mullerian hormone

1990 • 63 citations

Isolation of the rat gene for Mullerian inhibiting substance

1992 • 60 citations

Differential Regulation of Steady State 4-Ene Steroid 5α-Reductase Messenger Ribonucleic Acid Levels along the Rat Epididymis*

1991 • 55 citations

GATA-1 Transactivates the WT1 Hematopoietic Specific Enhancer

1995 • 54 citations

GATA-type zinc finger motif-containing sequences and chorion gene transcription factors of the silkworm Bombyx mori.

1994 • 51 citations

Regulation of Drosophila yolk protein Genes by an Ovary-Specific GATA Factor

1995 • 36 citations

Sex- and tissue-specific Bkm(GATA)-binding protein in the germ cells of heterogametic sex.

1994 • 29 citations

Expression of inhibin α-subunit gene during mouse gametogenesis

1990 • 26 citations