Male development of chromosomally female mice transgenic for Sry

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

1990 • 3,134 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

1990 • 1,630 citations

Chemical Mutagens. Principles and Methods for Their Detection.

1974 • 1,473 citations

A SEX-CHROMOSOME ANOMALY IN A CASE OF GONADAL DYSGENESIS (TURNER'S SYNDROME)

1959 • 1,360 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

A Case of Human Intersexuality Having a Possible XXY Sex-Determining Mechanism

1959 • 1,057 citations

Genetic evidence equating SRY and the testis-determining factor

1990 • 972 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Expression of a candidate sex-determining gene during mouse testis differentiation

1990 • 834 citations

Studies on Sex Differentiation in Mammals

1973 • 558 citations

A human XY female with a frame shift mutation in the candidate testis-determining gene SRY

1990 • 409 citations

Sex-reversed mice: XX and XO males

1971 • 350 citations

THE Y-CHROMOSOME AS THE BEARER OF MALE DETERMINING FACTORS IN THE MOUSE

1959 • 312 citations

Genetic evidence that ZFY is not the testis-determining factor

1989 • 305 citations

XY female mice resulting from a heritable mutation in the primary testis determining gene, Tdy

1990 • 304 citations

Most classical Mus musculus domesticus laboratory mouse strains carry a Mus musculus musculus Y chromosome

1985 • 227 citations

Cell-autonomous action of the testis-determining gene: Sertoli cells are exclusively XY in XX ↔XY chimaeric mouse testes

1988 • 193 citations

Zfy gene expression patterns are not compatible with a primary role in mouse sex determination

1989 • 178 citations

Chromosome Mapping and Expression of a Putative Testis-Determining Gene in Mouse

1989 • 146 citations

Mechanisms of sex differentiation in animals and man

1981 • 146 citations

Spermatogenic failure in male mice lacking H–Y antigen

1986 • 142 citations

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.

1990 • 123 citations

The pseudoautosomal boundary in man is defined by an Alu repeat sequence inserted on the Y chromosome

1989 • 111 citations

Aberrant chromosomal sex-determining mechanisms in mammals, with special reference to species with XY females

1988 • 105 citations

Duplication, Deletion, and Polymorphism in the Sex-Determining Region of the Mouse Y Chromosome

1989 • 103 citations

Sex determination in mammals

1988 • 101 citations

Fertile females produced by inactivation of an X chromosome of ‘sex-reversed’ mice

1982 • 97 citations

Analysis of the testes of H-Y negative XOSxrb mice suggests that the spermatogenesis gene (Spy) acts during the differentiation of the A spermatogonia

1989 • 91 citations

Duplication of an Xp segment that includes the ZFX locus causes sex inversion in man

1989 • 87 citations

Retarded development of XO conceptuses during early pregnancy in the mouse

1983 • 83 citations

Somatic and germ-cell sex in mammals

1988 • 63 citations

A cytogenetic investigation of inherited true hermaphroditism in BALB/cWt mice

1980 • 61 citations

Numerical Sex-Chromosome Anomalies in Mammals: Their Spontaneous Occurrence and Use in Mutagenesis Studies

1976 • 60 citations

Normal structure and expression of Zfy genes in XY female mice mutant in Tdy

1990 • 54 citations

XY follicle cells in the ovaries of XO/XY and XO/XY/XYY mosaic mice

1991 • 47 citations

Autosomal genes involved in mammalian primary sex determination

1988 • 43 citations

A ZFY-negative 46,XX true hermaphrodite is positive for the Y pseudoautosomal boundary

1990 • 41 citations

Control mechanisms of testicular differentiation

1988 • 34 citations