In vitro insertion of the 22-kD peroxisomal membrane protein into isolated rat liver peroxisomes.

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

Small heat shock proteins are molecular chaperones.

1993 • 1,376 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 • 1,175 citations

A conserved tripeptide sorts proteins to peroxisomes.

1989 • 1,113 citations

Biogenesis of Peroxisomes

1985 • 1,108 citations

Mitochondrial protein import

1989 • 820 citations

A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase.

1991 • 629 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures

1989 • 491 citations

Protein Translocation Across Membranes

1988 • 482 citations

Identification of a peroxisomal targeting signal at the carboxy terminus of firefly luciferase.

1987 • 481 citations

What drives the translocation of proteins?

1992 • 415 citations

Mechanism of membrane damage by streptolysin-O

1985 • 398 citations

The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily.

1990 • 395 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Structural and functional similarities of bovine alpha-crystallin and mouse small heat-shock protein. A family of chaperones.

1993 • 375 citations

Polypeptide and phospholipid composition of the membrane of rat liver peroxisomes: comparison with endoplasmic reticulum and mitochondrial membranes.

1982 • 374 citations

Identification of peroxisomal targeting signals located at the carboxy terminus of four peroxisomal proteins.

1988 • 338 citations

Functional Architecture of the Nicotinic Acetylcholine Receptor: From Electric Organ to Brain

1991 • 327 citations

THE MITOCHONDRIAL PROTEIN IMPORT APPARATUS

1990 • 311 citations

The Structure and Insertion of Integral Proteins in Membranes

1990 • 304 citations

Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting

1991 • 288 citations

Biogenesis of peroxisomes: intracellular site of synthesis of catalase and uricase.

1978 • 284 citations

Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: Analysis of biochemical mutants of SRP

1988 • 248 citations

The pas8 mutant of Pichia pastoris exhibits the peroxisomal protein import deficiencies of Zellweger syndrome cells--the PAS8 protein binds to the COOH-terminal tripeptide peroxisomal targeting signal, and is a member of the TPR protein family [published erratum appears in J Cell Biol 1993 Sep;122(5):following 1143]

1993 • 246 citations

[4] Estimation of biomass in growing cell lines by adenosine triphosphate assay

1986 • 234 citations

Requirement of GTP Hydrolysis for Dissociation of the Signal Recognition Particle from Its Receptor

1991 • 222 citations

Synthesis of a major integral membrane polypeptide of rat liver peroxisomes on free polysomes.

1984 • 194 citations

Translocation of acyl-CoA oxidase into peroxisomes requires ATP hydrolysis but not a membrane potential.

1987 • 191 citations

Peroxisome biogenesis revisited

1989 • 189 citations

Transport of F₁‐ATPase subunit β into mitochondria depends on both a membrane potential and nucleoside triphosphates

1986 • 182 citations

Mitochondrial precursor protein. Effects of 70-kilodalton heat shock protein on polypeptide folding, aggregation, and import competence.

1990 • 170 citations

Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome

1990 • 169 citations

Receptor classes and the transmitter-gated ion channels

1992 • 153 citations

Antibodies directed against the peroxisomal targeting signal of firefly luciferase recognize multiple mammalian peroxisomal proteins.

1990 • 133 citations

Cytosol-dependent peroxisomal protein import in a permeabilized cell system.

1993 • 129 citations

An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore.

1990 • 128 citations

Chapter 4 Poration by α-Toxin and Streptolysin O: An Approach to Analyze Intracellular Processes

1989 • 126 citations

Biosynthesis and intracellular transport of enzymes of peroxisomal beta-oxidation.

1984 • 124 citations

Synthesis of catalase in two cell-free protein-synthesizing systems and in rat liver

1978 • 121 citations

Post-translational import of fatty acyl-CoA oxidase and catalase into peroxisomes of rat liver in vitro.

1985 • 92 citations

Biosynthesis of Membrane Polypeptides of Rat Liver Peroxisomes1

1987 • 87 citations

Integral membrane polypeptides of rat liver peroxisomes: Topology and response to different metabolic states

1987 • 79 citations

Protein transport across the ER membrane

1990 • 75 citations

Purification of Membrane Polypeptides of Rat Liver Peroxisomes1

1986 • 70 citations

Characterization of the integral membrane polypeptides of rat liver peroxisomes isolated from untreated and clofibrate-treated rats

1991 • 61 citations

Import of Firefly Luciferase into Mammalian Peroxisomes in Vivo Requires Nucleoside Triphosphates

1993 • 53 citations

Peroxisomal protein import In vivo evidence for a novel ranslocation competent compartment

1992 • 52 citations

Import of Firefly Luciferase into Peroxisomes of Permeabilized Chinese Hamster Ovary Cells: A Model System to Study Peroxisomal Protein Import in Vitro

1993 • 49 citations

Improved isolation and purification of rat liver peroxisomes by combined rate zonal and equilibrium density centrifugation

1985 • 46 citations

Biochemical effects and zonal heterogeneity of peroxisome proliferation induced by perfluorocarboxylic acids in rat liver

1989 • 46 citations

Membrane topology of the 22 kDa integral peroxisomal membrane protein

1993 • 42 citations

Biogenesis of peroxisomes in mammals

1992 • 10 citations